Non-Invasive Quantitation of Myocardial Fibrosis Using Combined Tissue Harmonic Imaging and Integrated Backscatter Analysis in Dilated Cardiomyopathy

Cardiology ◽  
2006 ◽  
Vol 108 (1) ◽  
pp. 11-17 ◽  
Author(s):  
Reiko Mizuno ◽  
Shinichi Fujimoto ◽  
Yoshihiko Saito ◽  
Shinobu Nakamura
Keyword(s):  
Dilated Cardiomyopathy ◽  
Myocardial Fibrosis ◽  
Harmonic Imaging ◽  
Tissue Harmonic Imaging ◽  
Integrated Backscatter ◽  
Non Invasive

Is the tissue harmonic imaging useful for estimation of the myocardial fibrosis in patients with cardiomyopathy?

1999 ◽  
Vol 5 (3) ◽  
pp. 90
Author(s):  
Reiko Mizuno ◽  
Shinichi Fujimoto ◽  
Toshio Hashimoto ◽  
Kazuhiro Dohi
Keyword(s):  
Myocardial Fibrosis ◽  
Harmonic Imaging ◽  
Tissue Harmonic Imaging

Non-invasive Quantification of Myocardial Fibrosis in Diabetic Cardiomyopathy: T1 Mapping or Integrated Backscatter?

2010 ◽  
Vol 19 ◽  
pp. S190-S191
Author(s):  
C. Jellis ◽  
J. Wright ◽  
J. Sacre ◽  
D. Kennedy ◽  
B. Haluska ◽  
...  
Keyword(s):  
Myocardial Fibrosis ◽  
Diabetic Cardiomyopathy ◽  
T1 Mapping ◽  
Integrated Backscatter ◽  
Non Invasive

scholarly journals Association Between Echocardiographic Non-invasive Myocardial Work Indices and Myocardial Fibrosis in Patients With Dilated Cardiomyopathy

2021 ◽  
Vol 8 ◽  
Author(s):  
Cunying Cui ◽  
Yanan Li ◽  
Yuanyuan Liu ◽  
Danqing Huang ◽  
Yanbin Hu ◽  
...  
Keyword(s):  
Dilated Cardiomyopathy ◽  
Myocardial Fibrosis ◽  
Global Longitudinal Strain ◽  
Left Ventricular ◽  
Qualitative Assessment ◽  
Operating Characteristics ◽  
Systolic Volume ◽  
Non Invasive ◽  
Constructive Work ◽  
Global Work

Objectives: To analyze the association between global myocardial work indices evaluated by non-invasive left ventricular (LV) pressure-strain loop (PSL) and LV myocardial fibrosis in patients with dilated cardiomyopathy (DCM).Methods: A total of 57 patients with DCM were included in this prospective study. Global work index (GWI), global constructive work (GCW), global wasted work (GWW), global work efficiency (GWE) and global longitudinal strain (GLS) were measured using LVPSL. LV volumes and LV ejection fraction (LVEF) were evaluated using cardiac magnetic resonance imaging (CMRI), LV myocardial fibrosis was estimated at CMRI by qualitative assessment of late gadolinium enhancement (LGE). According to the CMRI, the studied population was divided into two groups, namely: patients without LGE (LGE-) and patients with LGE (LGE+).Results: The LGE+ group presented with increased age, LV end systolic volume (LVESV) index and reduced GWI, GCW, GWE, GLS, CMRI-derived LVEF (LVEFCMRI), the differences between the two groups were statistically significant (P < 0.05). After correcting for age and LVESV index, LVEFCMRI, GLS, GWI, GCW, and GWE retained independent associations with LV myocardial fibrosis. According to receiver operating characteristics (ROC) analysis, LVEFCMRI, and GCW showed larger AUC and higher accuracy, sensitivity, and specificity than GLS, the accuracy of predicting LV myocardial fibrosis ranged from high to low as: LVEFCMRI, GCW, GWE, GWI, and GLS.Conclusions: LVEFCMRI, GWI, GCW, GWE, and GLS remained significant predictors of LV myocardial fibrosis. LVEFCMRI, and GCW appeared to better predict LV myocardial fibrosis compared with GLS.

Association between integrated backscatter and arrhythmia in patients with ischemic dilated cardiomyopathy

2021 ◽  
Author(s):  
Ekrem Bilal Karaayvaz ◽  
Berat Engin ◽  
Kivanc Yalin ◽  
Pelin Karaca Ozer ◽  
Derya Baykiz ◽  
...  
Keyword(s):  
Dilated Cardiomyopathy ◽  
Integrated Backscatter

scholarly journals Predictive values of multiple non-invasive markers for myocardial fibrosis in hypertrophic cardiomyopathy patients with preserved ejection fraction

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Yumin Li ◽  
Jia Liu ◽  
Yukun Cao ◽  
Xiaoyu Han ◽  
Guozhu Shao ◽  
...  
Keyword(s):  
Hypertrophic Cardiomyopathy ◽  
Ejection Fraction ◽  
Myocardial Fibrosis ◽  
Troponin I ◽  
Myocardial Strain ◽  
Left Ventricular ◽  
Preserved Ejection Fraction ◽  
Predictive Values ◽  
Non Invasive ◽  
Potential Biomarker

AbstractMyocardial fibrosis assessed by late gadolinium enhancement (LGE) on cardiovascular magnetic resonance (CMR) is associated with cardiovascular outcomes in hypertrophic cardiomyopathy (HCM) patients, but little is known about the utility of non-invasive markers for detecting LGE. This study aims to explore the association between cardiac-specific biomarkers, CMR myocardial strain, left ventricular (LV) hypertrophy and LGE in HCM patients with preserved ejection fraction (EF) and investigate the predictive values of these indexes for LGE. We recruited 33 healthy volunteers and 86 HCM patients with preserved EF to undergo contrast-enhanced CMR examinations. In total, 48 of 86 HCM patients had the presence of LGE. The LGE-positive patients had significant higher serum high-sensitivity cardiac troponin I (hs-cTnI) and N-terminal pro b-type natriuretic peptide (Nt-proBNP) levels and lower global longitudinal (GLS) and circumferential (GCS) strains than the LGE-negative group. The LGE% was independently associated with the Nt-proBNP levels, GCS, LV end-diastolic maximum wall thickness (MWT) and beta-blocker treatment. In the receiver operating characteristic curve analysis, the combined parameters of Nt-proBNP ≥ 108.00 pg/mL and MWT ≥ 17.30 mm had good diagnostic performance for LGE, with a specificity of 81.25% and sensitivity of 70.00%. These data indicate that serum Nt-proBNP is a potential biomarker associated with LGE% and, combined with MWT, were useful for identifying myocardial fibrosis in HCM patients with preserved EF. Additionally, LV GCS may be a more sensitive indicator for reflecting the presence of myocardial fibrosis than GLS.

Sign in / Sign up

Export Citation Format

Share Document