The Role of Immune Response to Staphylococcus aureus Superantigens and Disease Severity in Relation to the Sensitivity to Tacrolimus in Atopic Dermatitis

2006 ◽  
Vol 141 (3) ◽  
pp. 281-289 ◽  
Author(s):  
Hisayo Fukushima ◽  
Toshihiko Hirano ◽  
Naoko Shibayama ◽  
Keishi Miwa ◽  
Tomonobu Ito ◽  
...  
2020 ◽  
Vol 8 (6) ◽  
pp. 7
Author(s):  
Suzan Yousif Jasim ◽  
Mayssaa E. Abdalah ◽  
Bahir Abdul Razzaq Mshimesh

2018 ◽  
Vol 27 (2) ◽  
pp. 107-112
Author(s):  
Amal A. Wafy ◽  
Wageih S. Elnaghy ◽  
Nashwa El-Far ◽  
Sara A. Hamam ◽  
Mohammed El-Gamasy

Toxins ◽  
2019 ◽  
Vol 11 (6) ◽  
pp. 321 ◽  
Author(s):  
Fabio Seiti Yamada Yoshikawa ◽  
Josenilson Feitosa de Lima ◽  
Maria Notomi Sato ◽  
Yasmin Álefe Leuzzi Ramos ◽  
Valeria Aoki ◽  
...  

Atopic dermatitis (AD) is a chronic and inflammatory skin disease with intense pruritus and xerosis. AD pathogenesis is multifactorial, involving genetic, environmental, and immunological factors, including the participation of Staphylococcus aureus. This bacterium colonizes up to 30–100% of AD skin and its virulence factors are responsible for its pathogenicity and antimicrobial survival. This is a concise review of S. aureus superantigen-activated signaling pathways, highlighting their involvement in AD pathogenesis, with an emphasis on skin barrier disruption, innate and adaptive immunity dysfunction, and microbiome alterations. A better understanding of the combined mechanisms of AD pathogenesis may enhance the development of future targeted therapies for this complex disease.


Author(s):  
Ankie Lebon ◽  
Joost A. M. Labout ◽  
Henri A. Verbrugh ◽  
Vincent W. V. Jaddoe ◽  
Albert Hofman ◽  
...  

2017 ◽  
Vol 12 (14) ◽  
pp. 1327-1334 ◽  
Author(s):  
Simone Saintive ◽  
Eliane Abad ◽  
Dennis de C Ferreira ◽  
Mayra Stambovsky ◽  
Fernanda S Cavalcante ◽  
...  

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