The Role of Neural and Mechanical Influences in Maintaining Normal Fast and Slow Muscle Properties

2006 ◽  
Vol 182 (3-4) ◽  
pp. 129-142 ◽  
Author(s):  
Yoshinobu Ohira ◽  
Tomoo Yoshinaga ◽  
Makoto Ohara ◽  
Fuminori Kawano ◽  
Xiao Dong Wang ◽  
...  
PLoS ONE ◽  
2013 ◽  
Vol 8 (11) ◽  
pp. e78246 ◽  
Author(s):  
Tibor Istvan Toth ◽  
Martyna Grabowska ◽  
Joachim Schmidt ◽  
Ansgar Büschges ◽  
Silvia Daun-Gruhn

2009 ◽  
Vol 33 (4) ◽  
pp. 483-492 ◽  
Author(s):  
Edyta Brzóska ◽  
Marta Przewoźniak ◽  
Iwona Grabowska ◽  
Katarzyna Jańczyk-Ilach ◽  
Jerzy Moraczewski

2016 ◽  
Vol 11 (8) ◽  
pp. 1293 ◽  
Author(s):  
Gang Li ◽  
Qing-shan Li ◽  
Wen-bin Li ◽  
Jian Wei ◽  
Wen-kai Chang ◽  
...  

Author(s):  
Allison White ◽  
Hannah Abbott ◽  
Alfonse Masi ◽  
Kalyani Nair

Ankylosing spondylitis (AS) is a degenerative rheumatological disorder that mainly affects the spine. It has been reported that different degrees of human resting myofascial tone (HRMT) would affect spinal stability and may predispose to the respective curvature deformities of adolescent idiopathic scoliosis (AIS) and the enthesopathy of ankylosing spondylitis (AS). Although osteoligamentous impacts are prominently recognized in many chronic spine and low back conditions, no research has been performed on the possible role of passive axial (spinal) myofascial tone as a causative factor. In this particular study, the passive muscle properties of the lower lumbar regions of 24 healthy adults and 24 adult AS subjects were examined. Our recent publications examined the linear elastic properties among normal and AS subjects. In this study, those analyses are expanded to include detailed analysis and correlations of the linear elastic property of stiffness to two viscoelastic properties: stress relaxation time (SRT) and creep. Analyzed data supports the hypothesis that resting muscle properties of the lower lumbar muscles hold significance in differentiation of human back health between healthy and diseased subjects, but more testing should be performed to support this study’s results.


1982 ◽  
Vol 202 (2) ◽  
pp. 289-301 ◽  
Author(s):  
Giovanni Salviati ◽  
Pompeo Volpe ◽  
Sergio Salvatori ◽  
Romeo Betto ◽  
Ernesto Damiani ◽  
...  

1. Microsomes were isolated from rabbit fast-twitch and slow-twitch muscle and were separated into heavy and light fractions by centrifugation in a linear (0.3–2m) sucrose density gradient. The membrane origin of microsomal vesicles was investigated by studying biochemical markers of the sarcoplasmic-reticulum membranes and of surface and T-tubular membranes, as well as their freeze-fracture properties. 2. Polyacrylamide-gel electrophoresis showed differences in the Ca2+-dependent ATPase/calsequestrin ratio between heavy and light fractions, which were apparently consistent with their respective origin from cisternal and longitudinal sarcoplasmic reticulum, as well as unrelated differences, such as peptides specific to slow-muscle microsomes (mol.wts. 76000, 60000, 56000 and 45000). 3. Freeze-fracture electron microscopy of muscle microsomes demonstrated that vesicles truly derived from the sarcoplasmic reticulum, with an average density of 9nm particles on the concave face of about 3000/μm2 for both fast and slow muscle, were admixed with vesicles with particle densities below 1000/μm2. 4. As determined in the light fractions, the sarcoplasmic-reticulum vesicles accounted for 84% and 57% of the total number of microsomal vesicles, for fast and slow muscle respectively. These values agreed closely with the percentage values of Ca2+-dependent ATPase protein obtained by gel densitometry. 5. The T-tubular origin of vesicles with a smooth concave fracture face in slow-muscle microsomes is supported by their relative high content in total phospholipid and cholesterol, compared with the microsomes of fast muscle, and by other correlative data, such as the presence of (Na++K+)-dependent ATPase activity and of low amounts of Na+-dependent membrane phosphorylation. 6. Among intrinsic sarcoplasmic-reticulum membrane proteins, a proteolipid of mol.wt. 12000 is shown to be identical in the microsomes of both fast and slow muscle and the Ca2+-dependent ATPase to be antigenically and catalytically different, though electrophoretically homogeneous. 7. Basal Mg2+-activated ATPase activity was found to be high in light microsomes from slow muscle, but its identification with an enzyme different from the Ca2+-dependent ATPase is still not conclusive. 8. Enzyme proteins that are suggested to be specific to slow-muscle longitudinal sarcoplasmic reticulum are the flavoprotėin NADH:cytochrome b5 reductase (mol.wt. 32000), cytochrome b5 (mol.wt. 17000) and the stearoyl-CoA desaturase, though essentially by criteria of plausibility.


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