scholarly journals Surfactant Therapy: Present and Future Perspectives. Proceedings of the 21st International Workshop on Surfactant Replacement, Oslo, June 1–4, 2006

Neonatology ◽  
2006 ◽  
Vol 89 (4) ◽  
pp. 281-281
Keyword(s):  
International Workshop ◽  
Surfactant Therapy ◽  
Future Perspectives ◽  
Surfactant Replacement

scholarly journals Echography-Guided Surfactant Therapy to Improve Timeliness of Surfactant Replacement: A Quality Improvement Project

2019 ◽  
Vol 212 ◽  
pp. 137-143.e1 ◽  
Author(s):  
Roberto Raschetti ◽  
Nadya Yousef ◽  
Giulia Vigo ◽  
Gianluigi Marseglia ◽  
Roberta Centorrino ◽  
...  
Keyword(s):  
Quality Improvement ◽  
Quality Improvement Project ◽  
Surfactant Therapy ◽  
Improvement Project ◽  
Surfactant Replacement

scholarly journals Surfactant Replacement Therapy for Respiratory Distress Syndrome in the Newborn: A Review

2017 ◽  
Vol 40 (1) ◽  
pp. 26-30
Author(s):  
Tahsinul Amin ◽  
Mohammod Shahidullah
Keyword(s):  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Distress Syndrome ◽  
Pulmonary Hemorrhage ◽  
Surfactant Therapy ◽  
Respiratory Morbidity ◽  
Exogenous Surfactant ◽  
Surfactant Replacement ◽  
Surfactant Deficiency ◽  
Surfactant Replacement Therapy

Respiratory failure secondary to surfactant deficiency is a major cause of morbidity and mortality in low birth weight premature infants. Surfactant therapy substantially reduces mortality and respiratory morbidity for this population. Exogenous surfactant therapy has become well established in newborn infants with respiratory distress. Many aspects of its use have been well evaluated in high-quality trials and systematic reviews. Secondary surfactant deficiency also contributes to acute respiratory morbidity in late-preterm and term neonates with meconium aspiration syndrome, pneumonia/ sepsis, and perhaps pulmonary hemorrhage; surfactant replacement may be beneficial for these infants. This article summarizes the evidence and gives recommendations for the use of surfactant therapy for respiratory distress syndrome (RDS) in newborn.Bangladesh J Child Health 2016; VOL 40 (1) :26-30

Pharmaceutical Expenditure Is Unchanged with Ultrasound-Guided Surfactant Administration

2020 ◽  
Author(s):  
Daniele De Luca ◽  
Nadya Yousef
Keyword(s):  
Gestational Age ◽  
Financial Management ◽  
Lung Ultrasound ◽  
Pharmaceutical Expenditure ◽  
Surfactant Therapy ◽  
Preterm Neonates ◽  
Ultrasound Guided ◽  
Surfactant Replacement ◽  
Surfactant Administration ◽  
The Impact

Objective Semiquantitative lung ultrasound improves the timeliness of surfactant replacement, but its financial consequences are unknown. We aim to investigate if the ultrasound-guided surfactant administration influences the general costs of surfactant therapy for preterm neonates affected by respiratory distress syndrome. Study Design This is a pharmacoeconomic, retrospective, and before-and-after study investigating the impact of ultrasound-guided surfactant replacement (echography-guided Surfactant THERapy [ESTHER]) on pharmaceutical expenditure within the ESTHER initiative. Data extracted from the institutional official database hosted by the hospital administration for financial management were used for the analysis. We analyzed the number of surfactant administrations in neonates of gestational age ≤326/7 weeks, and the number of surfactant vials used from January 1, 2014 to June 30, 2014 (i.e., during the period of standard surfactant administration policy) and from July 1, 2016 to December 31, 2018 (that is during ESTHER policy). Results ESTHER did not modify surfactant use, as proportion of treated neonates with RDS receiving at least one surfactant dose (Standard: 21.3% vs. ESTHER: 20.9%; p = 0.876) or as proportion of used vials over the total number of vials opened for neonates of any gestational age (Standard: 37% vs. ESTHER: 35%; p = 0.509). Conclusion Ultrasound-guided surfactant replacement using a semiquantitative lung ultrasound score in preterm infants with RDS does not change the global use of surfactant and the related expenditure. Key Points

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