Assessment of Health-Related Quality of Life in Chronic Dialysis Patients with the COOP/WONCA Charts

2006 ◽  
Vol 104 (1) ◽  
pp. c7-c14 ◽  
Author(s):  
Francisco Martín-Díaz ◽  
Abilio Reig-Ferrer ◽  
Rosario Ferrer-Cascales
Keyword(s):  
Quality Of Life ◽  
Chronic Dialysis ◽  
Health Related Quality ◽  
Dialysis Patients ◽  
Related Quality ◽  
Health Related

MO822POLYPHARMACY NEGATIVELY AFFECTS HEALTH-RELATED QUALITY OF LIFE IN DIALYSIS PATIENTS

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
Julia Colombijn ◽  
Anna Bonenkamp ◽  
Anita Van Eck van der Sluijs ◽  
Alferso C Abrahams ◽  
Joost Bijlsma ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Health Related Quality ◽  
Dialysis Patients ◽  
Self Rated Health ◽  
Therapeutic Benefits ◽  
Significant Difference ◽  
Related Quality ◽  
Health Related ◽  
The Mean

Abstract Background and Aims Dialysis patients are often prescribed a large number of medications to improve metabolic control and manage co-existing comorbidities. However, several studies suggest that a large number of medications can also detrimentally affect their health-related quality of life (HRQoL). Therefore, this study aims to provide insight in the association between the number of medications and various aspects of HRQoL in dialysis patients. Method A multicentre study was conducted among dialysis patients from Dutch dialysis centres three months after initiation of dialysis as part of the ongoing prospective DOMESTICO study. The number of medications, defined as the number of concomitantly prescribed types of drugs, was obtained from electronic patient records. Primary outcome was HRQoL measured with the Physical Component Summary (PCS) score and Mental Component Summary (MCS) score (range 0-100) of the Short Form 12. Secondary outcomes were number of symptoms (range 0-30) measured with the Dialysis Symptoms Index and self-rated health (range 0-100) measured with the visual analogue scale of the EuroQol-5D-5L. Data were analysed using linear regression and adjusted for possible confounders, including age, sex, dialysis modality, and comorbidity. Analyses for MCS and number of symptoms were performed after categorising patients in tertiles according to their number of medications because assumptions of linearity were violated for these outcomes. Results A total of 162 patients were included. Mean age of patients was 58 ± 17 years, 35% were female, and 80% underwent haemodialysis. The mean number of medications was 12.2 ± 4.5. Mean PCS and MCS were 36.6 ± 10.2 and 46.8 ± 10.0, respectively. The mean number of symptoms was 12.3 ± 6.9 and mean self-rated health 60.1 ± 20.6. In adjusted analyses, PCS was 0.6 point lower for each additional medication (95%CI -0.9 – -0.2; p=0.002). MCS was 4.9 point lower (95%CI -8.8 – -1.0; p=0.01) and 1.0 point lower (95%CI -5.1 – 3.1; p=0.63) for the highest and middle tertiles of medications, respectively, compared to the lowest tertile. Patients in the highest tertile of medications reported 4.1 more symptoms compared to the lowest tertile (95%CI 1.5 – 6.6; p=0.002) but no significant difference in the number of symptoms was observed between the middle and lowest tertile. Self-rated health was 1.5 point lower for each medication (95%CI -2.2 – -0.7; p<0.001). Conclusion After adjustment for comorbidity and other confounders, a higher number of medications was associated with a lower PCS, MCS, and self-rated health in dialysis patients and with more symptoms. This suggests that it may be relevant to weigh expected therapeutic benefits of medication against their possible harmful effects on HRQoL. An unfavourable balance between expected benefits and impact on HRQoL might be ground to deviate from clinical guidelines, especially for patients with a limited life-expectancy and for whom a kidney transplant is unattainable.

Effects of sleep disorders and sedative–hypnotic medications on health-related quality of life in dialysis patients

2018 ◽  
Vol 51 (1) ◽  
pp. 163-174
Author(s):  
Chenfei Zheng ◽  
Jinglin Xu ◽  
Chaosheng Chen ◽  
Fan Lin ◽  
Rongrong Shao ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Sleep Disorders ◽  
Health Related Quality ◽  
Dialysis Patients ◽  
Related Quality ◽  
Health Related

scholarly journals Correction to: Use of the KDQOL-36™ for assessment of health-related quality of life among dialysis patients in the United States

2019 ◽  
Vol 20 (1) ◽  
Author(s):  
Dena E. Cohen ◽  
Andrew Lee ◽  
Scott Sibbel ◽  
Deborah Benner ◽  
Steven M. Brunelli ◽  
...  
Keyword(s):  
Quality Of Life ◽  
United States ◽  
The United States ◽  
Health Related Quality ◽  
Dialysis Patients ◽  
Related Quality ◽  
Health Related

Following publication of the original article [1], the authors reported an error in Figs. 3 and S3.

scholarly journals Health related quality of life of dialysis patients in Malaysia: Haemodialysis versus continuous ambulatory peritoneal dialysis

2019 ◽  
Vol 20 (1) ◽  
Author(s):  
Naren Kumar Surendra ◽  
Mohd Rizal Abdul Manaf ◽  
Lai Seong Hooi ◽  
Sunita Bavanandan ◽  
Fariz Safhan Mohamad Nor ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Peritoneal Dialysis ◽  
Continuous Ambulatory Peritoneal Dialysis ◽  
Health Related Quality ◽  
Dialysis Patients ◽  
Related Quality ◽  
Health Related
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