Transcription Factor Ets-1 Regulates Fibroblast Growth Factor-1-Mediated Angiogenesis in vivo: Role of Ets-1 in the Regulation of the PI3K/AKT/MMP-1 Pathway

2006 ◽  
Vol 43 (4) ◽  
pp. 327-337 ◽  
Author(s):  
Reza Forough ◽  
Brian Weylie ◽  
Charles Collins ◽  
Janet L. Parker ◽  
James Zhu ◽  
...  
Keyword(s):  
Transcription Factor ◽  
Growth Factor ◽  
Fibroblast Growth Factor ◽  
Fibroblast Growth

scholarly journals Dual role of FGF in proliferation and endoreplication of Drosophila tracheal adult progenitor cells

2019 ◽  
Vol 12 (1) ◽  
pp. 32-41
Author(s):  
Cristina de Miguel ◽  
Josefa Cruz ◽  
David Martín ◽  
Xavier Franch-Marro
Keyword(s):  
Transcription Factor ◽  
Growth Factor ◽  
Fibroblast Growth Factor ◽  
Progenitor Cells ◽  
Posterior Part ◽  
Dual Role ◽  
Fibroblast Growth ◽  
Fgf Signaling

Abstract Adult progenitor cells activation is a key event in the formation of adult organs. In Drosophila, formation of abdominal adult trachea depends on the specific activation of tracheal adult progenitors (tracheoblasts) at the Tr4 and Tr5 spiracular branches. Proliferation of these tracheoblasts generates a pool of tracheal cells that migrate toward the posterior part of the trachea by the activation of the branchless/fibroblast growth factor (Bnl/FGF) signaling to form the abdominal adult trachea. Here, we show that, in addition to migration, Bnl/FGF signaling, mediated by the transcription factor Pointed, is also required for tracheoblast proliferation. This tracheoblast activation relies on the expression of the FGF ligand bnl in their nearby branches. Finally, we show that, in the absence of the transcription factor Cut (Ct), Bnl/FGF signaling induces endoreplication of tracheoblasts partially by promoting fizzy-related expression. Altogether, our results suggest a dual role of Bnl/FGF signaling in tracheoblasts, inducing both proliferation and endoreplication, depending on the presence or absence of the transcription factor Ct, respectively.

613 Role of basic fibroblast growth factor in the regulation of rat basilar artery tone in vivo

1996 ◽  
Vol 25 ◽  
pp. S76
Author(s):  
Osamu Kadota ◽  
Yoshiaki Kumon ◽  
Saburo Sakaki ◽  
Seiji Matsuda ◽  
Masahiro Sakanaka
Keyword(s):  
Growth Factor ◽  
Fibroblast Growth Factor ◽  
Basic Fibroblast Growth Factor ◽  
Basilar Artery ◽  
Fibroblast Growth

In vivo angiogenesis in normal and portal hypertensive rats: role of basic fibroblast growth factor and nitric oxide

2001 ◽  
Vol 34 (5) ◽  
pp. 644-650 ◽  
Author(s):  
Cornel C Sieber ◽  
Lazar T Sumanovski ◽  
Michael Stumm ◽  
Maaike van der Kooij ◽  
Edouard Battegay
Keyword(s):  
Nitric Oxide ◽  
Growth Factor ◽  
Fibroblast Growth Factor ◽  
Basic Fibroblast Growth Factor ◽  
Fibroblast Growth ◽  
Hypertensive Rats

Role of basic fibroblast growth factor in the regulation of rat basilar artery tone in vivo

1995 ◽  
Vol 199 (2) ◽  
pp. 99-102 ◽  
Author(s):  
Osamu Kadota ◽  
Shinsuke Ohta ◽  
Yoshiaki Kumon ◽  
Saburo Sakaki ◽  
Seiji Matsuda ◽  
...  
Keyword(s):  
Growth Factor ◽  
Fibroblast Growth Factor ◽  
Basic Fibroblast Growth Factor ◽  
Basilar Artery ◽  
Fibroblast Growth

The role of basic fibroblast growth factor to enhance fetal intestinal mucosal cell regeneration in vivo

2009 ◽  
Vol 25 (8) ◽  
pp. 691-695 ◽  
Author(s):  
Atsushi Yoshida ◽  
Takuo Noda ◽  
Morimichi Tani ◽  
Takanori Oyama ◽  
Yasuhiro Watanabe ◽  
...  
Keyword(s):  
Growth Factor ◽  
Fibroblast Growth Factor ◽  
Basic Fibroblast Growth Factor ◽  
Cell Regeneration ◽  
Mucosal Cell ◽  
Fibroblast Growth ◽  
Intestinal Mucosal Cell
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