scholarly journals Familial Breast Cancer, Prevention, Risk Factors and Genetics – Highlights from the San Antonio Breast Cancer Symposium (SABCS) Poster Presentations

Breast Care ◽  
2006 ◽  
Vol 1 (2) ◽  
pp. 103-106
Author(s):  
Dirk Olaf Bauerschlag ◽  
Christian Schem ◽  
Christoph Mundhenke ◽  
Ivo Meinhold-Heerlein ◽  
Walter Jonat ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Cancer Prevention ◽  
Familial Breast Cancer ◽  
San Antonio ◽  
Breast Cancer Prevention ◽  
Breast Cancer Symposium ◽  
Poster Presentations

scholarly journals Modifiable Lifestyle Factors: Opportunities for (Hereditary) Breast Cancer Prevention - a Narrative Review

Breast Care ◽  
2018 ◽  
Vol 13 (2) ◽  
pp. 108-113 ◽  
Author(s):  
Jacqueline Lammert ◽  
Sabine Grill ◽  
Marion Kiechle
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Cancer Prevention ◽  
Healthy Lifestyle ◽  
Absolute Risk ◽  
Lifestyle Factors ◽  
Breast Cancer Prevention ◽  
The Impact

Increasing rates of obesity, lack of physical activity, sedentary behavior, and frequent alcohol consumption are major lifestyle-related risk factors for breast cancer. In fact, it has been estimated that about one-third of breast cancer cases are attributable to factors women can change. Most research has focused on examining the impact of one single exposure on breast cancer risk while adjusting for other risk modifiers. Capitalizing on big data, major efforts have been made to evaluate the combined impact of well-established lifestyle factors on overall breast cancer risk. At the individual level, data indicate that even simple behavior modifications could have a considerable impact on breast cancer prevention. Moreover, there is emerging new evidence that adopting a healthy lifestyle may be particularly relevant for women with hereditary susceptibility to breast cancer. On the absolute risk scale, studies suggest that the presence of certain risk factors, such as excessive body weight, had a substantially higher impact on breast cancer risk if women had a hereditary predisposition to cancer. The existing body of knowledge gives the medical professionals guidance as to which factors to focus on when counseling patients. However, well-designed randomized controlled trials utilizing objective methods are crucial to providing concrete recommendations.

scholarly journals Women’s health behaviors and selected determinants in breast cancer prevention / Zachowania zdrowotne kobiet i wybrane ich determinanty w profilaktyce raka piersi

2016 ◽  
Vol 15 (2) ◽  
pp. 26-33
Author(s):  
Barbara Ślusarska ◽  
Ewa Łochowska ◽  
Honorata Piasecka ◽  
Katarzyna Szczekala ◽  
Grzegorz Józef Nowicki
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Health Behaviors ◽  
Cancer Prevention ◽  
Women’S Health ◽  
Women's Health ◽  
Clinical Breast Examination ◽  
Breast Cancer Prevention ◽  
Breast Examination ◽  
Clinical Breast

Abstract Introduction. Breast cancer is the most common malignant cancer in women in Poland. Health behaviors concerning lifestyle and breast self-examination (BSE) constitute a significant element of early prevention.Aim. To determine the level of the women’s health behaviors and selected determinants in breast cancer prevention.Material and methods. The study was carried out among 144 female residents of Radom County from March to April, 2014. The diagnostic survey method was applied with an author’s questionnaire compiled for this purpose.Results. The average level of health behavior was presented by 64.6 % of the women while the low level by 32.6 %. The evaluation of awareness of risk factors and breast cancer prevention revealed that 54.9% of the respondents obtained the maximum score. The lowest result equals 19.3 % whereas the highest one is 88.6%. The total of 53.5 % of the females declared embarrassment on clinical breast examination (CBE).Conclusions. A higher level of health behaviors is found in the women with higher education and greater knowledge of breast cancer risk factors. The respondents who experience greater embarrassment during clinical breast examination present a lower level of health behaviors

Critical assessment of new risk factors for breast cancer: considerations for development of an improved risk prediction model

2007 ◽  
Vol 14 (2) ◽  
pp. 169-187 ◽  
Author(s):  
Richard J Santen ◽  
Norman F Boyd ◽  
Rowan T Chlebowski ◽  
Steven Cummings ◽  
Jack Cuzick ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Prediction Model ◽  
Cancer Prevention ◽  
Risk Prediction ◽  
Breast Cancer Prevention ◽  
Risk Prediction Model ◽  
Clinical Material ◽  
Collaborative Group ◽  
Density State

The majority of candidates for breast cancer prevention have not accepted tamoxifen because of the perception of an unfavorable risk/benefit ratio and the acceptance of raloxifene remains to be determined. One means of improving this ratio is to identify women at very high risk of breast cancer. Family history, age, atypia in a benign biopsy, and reproductive factors are the main parameters currently used to determine risk. The most powerful risk factor, mammographic density, is not presently employed routinely. Other potentially important factors are plasma estrogen and androgen levels, bone density, weight gain, age of menopause, and fracture history, which are also not currently used in a comprehensive risk prediction model because of lack of prospective validation. The Breast Cancer Prevention Collaborative Group (BCPCG) met to critically examine and prioritize risk factors that might be selected for further testing by multivariate analysis using existing clinical material. The BCPCG reached a consensus that quantitative breast density, state of the art plasma estrogen and androgen measurements, history of fracture and height loss, BMI, and waist–hip ratio had sufficient priority for further testing. As a practical approach, these parameters could be added to the existing Tyrer–Cuzick model which encompasses factors included in both the Claus and Gail models. The BCPCG analyzed potentially available clinical material from previous prospective studies and determined that a large case/control study to evaluate these new factors might be feasible at this time.

scholarly journals Early Alcohol Use Initiation, Obesity, Not Breastfeeding, and Residence in a Rural Area as Risk Factors for Breast Cancer: A Case-Control Study

Cancers ◽  
2021 ◽  
Vol 13 (16) ◽  
pp. 3925
Author(s):  
Dorota Anna Dydjow-Bendek ◽  
Paweł Zagożdżon
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Alcohol Use ◽  
Cancer Prevention ◽  
Rural Area ◽  
Case Control Study ◽  
Case Control ◽  
Breast Cancer Prevention ◽  
Alcohol Use Initiation ◽  
Control Study

The aim of this study was to determine the risk factors for breast cancer in the Polish population. In total, 201 Polish women newly diagnosed with breast cancer and 201 one-to-one age-matched healthy controls participated in this case-control study. Data on sociodemographic characteristics, reproductive and menstrual history, medical history, lifestyle factors, and anthropometric measurements were collected by the interviewers. Odds ratios and 95% confidence intervals were obtained using multivariate unconditional logistic regression models controlling for potential confounders. Significant relationships were observed between BMI, alcohol use initiation, breastfeeding, education, and place of residence. Obese women had a higher risk of breast cancer than women with a BMI < 30 (OR = 1.9; 95% CI: 1.16 to 3.04). Early alcohol use initiation (≤15 years) was associated with an almost two-fold higher risk of breast cancer (OR = 1.98, 95% CI: 1.06 to 3.69). Breastfeeding for less than 3 months (OR = 2.3, 95% CI: 1.52 to 3.5), receiving a basic and vocational education (OR = 2.5, 95% CI: 1.49 to 4.19), and living in a rural area (OR = 1.7, 95% CI: 1.05 to 2.9) increased the risk of breast cancer. Prevention activities for breast cancer are already needed in adolescents and young women. A much greater emphasis should also be placed on breast cancer prevention campaigns in rural areas in Poland.

Effect of tamoxifen on venous thrombosis risk factors in women without cancer: the Breast Cancer Prevention Trial

2002 ◽  
Vol 120 (1) ◽  
pp. 109-116 ◽  
Author(s):  
Mary Cushman ◽  
Joseph P. Costantino ◽  
Edwin G. Bovill ◽  
D. Lawrence Wickerham ◽  
Lenore Buckley ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Venous Thrombosis ◽  
Cancer Prevention ◽  
Breast Cancer Prevention ◽  
Prevention Trial ◽  
Breast Cancer Prevention Trial ◽  
Thrombosis Risk
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