scholarly journals Hormonal Regulation of Postnatal Growth in Children Born Small for Gestational Age

2006 ◽  
Vol 65 (3) ◽  
pp. 70-74 ◽  
Author(s):  
S. Cianfarani ◽  
C. Ladaki ◽  
C. Geremia
Keyword(s):  
Gestational Age ◽  
Small For Gestational Age ◽  
Hormonal Regulation ◽  
Postnatal Growth

Hormonal regulation of postnatal growth from birth to age six months in Small-for-Gestational - Age children

2016 ◽  
Vol 7 (3) ◽  
pp. 104-110
Author(s):  
Kristina F Islamova ◽  
Dmitriy O Ivanov ◽  
Yuriy V Petrenko ◽  
Elizaveta A Kurzina
Keyword(s):  
Insulin Sensitivity ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Hormonal Regulation ◽  
Later Life ◽  
Postnatal Growth ◽  
Blood Levels ◽  
Model Assessment ◽  
Appropriate For Gestational Age ◽  
Catch Up

This article is devoted to the investigation hormonal mechanisms of postnatal growth from birth to age six months in small for gestational age children (SGA) with asymmetrical and asymmetrical IUGR. The IGF-1 and GH levels, insulin sensitivity (by homeostasis model assessment (HOMA-IR)) were measured blood at 3 and 6 months of age. The prospective study includes 40 SGA infants (group 1) - 24 - with asymmetrical (1a) and 16 with symmetrical IUGR babies (1b) and 17 appropriate for gestational age (AGA) infants (group 2). Most SGA infants showed rapid, or “catch-up” postnatal growth. Symmetrical IUGR infants with “catch-up” growth had higher IGF-1 and growth GH levels at 3 month of age than asymmetrical IUGR with “catch-up” growth (p < 0,05). From 3 to 6 months of age 77 % of infants with “catch-up” growth showed retardation of growth velocity. At 6 month of age SGA infants with “catch-up” growth had lower IGF-1, GH blood levels and HOMA-IR than at 3 months of age (p < 0,05). Infants without “catch-up” growth had similar hormone levels at 3 and 6 months of age. We suppose, that these changes of “GH - IGF-1” axis and insulin sensitivity at age 3 and 6 months in SGA infants are the mechanisms, which promote the postnatal growth. It can be assumed that the same mechanisms may underlie metabolic disorders in later life.

scholarly journals Metabolic implications of GH treatment in small for gestational age

2007 ◽  
Vol 157 (suppl_1) ◽  
pp. S47-S50 ◽  
Author(s):  
E M Delemarre ◽  
J Rotteveel ◽  
H A Delemarre-van de Waal
Keyword(s):  
Lipid Metabolism ◽  
Gestational Age ◽  
Growth Retardation ◽  
Small For Gestational Age ◽  
Postnatal Growth ◽  
Gh Treatment ◽  
Increased Risk ◽  
Igf I

Fetal growth retardation is associated with decreased postnatal growth, resulting in a lower adult height. In addition, a low birth weight is associated with an increased risk of developing diseases during adulthood, such as insulin resistance, type 2 diabetes mellitus, hypertension, dyslipidemia, and cardiovascular diseases. Children with persistent postnatal growth retardation, i.e., incomplete catchup growth, can be treated with human GH. The GH/IGF-I axis is involved in the regulation of carbohydrate and lipid metabolism. The question of whether treatment with GH in children born small for gestational age (SGA) has long-term implications with respect to glucose/insulin and lipid metabolism has not been answered yet. In this article, the available data are reviewed.

The Optimal Postnatal Growth Trajectory for Term Small for Gestational Age Babies: A Prospective Cohort Study

2015 ◽  
Vol 166 (1) ◽  
pp. 54-58.e3 ◽  
Author(s):  
Xiaoping Lei ◽  
Yan Chen ◽  
Jiangfeng Ye ◽  
Fengxiu Ouyang ◽  
Fan Jiang ◽  
...  
Keyword(s):  
Cohort Study ◽  
Prospective Cohort Study ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Prospective Cohort ◽  
Postnatal Growth ◽  
Growth Trajectory

Birth Size, Postnatal Growth and Growth during Growth Hormone Treatment in Small-for-Gestational-Age Children: Associations with IGF1 Gene Polymorphisms and Haplotypes?

2009 ◽  
Vol 72 (1) ◽  
pp. 15-24 ◽  
Author(s):  
Wietske A. Ester ◽  
Joyce B. van Meurs ◽  
Nicolette J. Arends ◽  
Andr&eacute; G. Uitterlinden ◽  
Maria A. de Ridder ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Gene Polymorphisms ◽  
Growth Hormone Treatment ◽  
Hormone Treatment ◽  
Postnatal Growth ◽  
Birth Size ◽  
I Gene

scholarly journals Role of insulin-like gRowth factoR-1 in fetal and eaRly postnatal gRowth in childRen boRn small foR gestational age

2013 ◽  
Vol 6 (6) ◽  
pp. 36-39
Author(s):  
Kristina F. islamova ◽  
◽  
YurY v . PetrenKo ◽  
DmitrY o. ivanov ◽  
soFia n. FiliPPova ◽  
...  
Keyword(s):  
Growth Factor ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Postnatal Growth ◽  
Insulin Like Growth Factor

scholarly journals Postnatal growth in children born small for gestational age with and without smoking mother

2019 ◽  
Vol 85 (7) ◽  
pp. 961-966
Author(s):  
Linda Lindström ◽  
Anna-Karin Wikström ◽  
Eva Bergman ◽  
Ajlana Mulic-Lutvica ◽  
Ulf Högberg ◽  
...  
Keyword(s):  
Gestational Age ◽  
Small For Gestational Age ◽  
Postnatal Growth ◽  
Smoking Mother

Children Born Small-for-Gestational Age: Postnatal Growth and Hormonal Status

1998 ◽  
Vol 49 (Suppl. 2) ◽  
pp. 7-13 ◽  
Author(s):  
Kerstin Albertsson-Wikland ◽  
Margaret Boguszewski ◽  
Johan Karlberg
Keyword(s):  
Gestational Age ◽  
Small For Gestational Age ◽  
Postnatal Growth ◽  
Hormonal Status

Postnatal growth of children born small for gestational age

1997 ◽  
Vol 86 (S423) ◽  
pp. 193-195 ◽  
Author(s):  
K. Albertsson-Wikland ◽  
J. Karlberg
Keyword(s):  
Gestational Age ◽  
Small For Gestational Age ◽  
Postnatal Growth
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