Serum Starvation and Growth Factor Receptor Expression in Vascular Smooth Muscle Cells

2006 ◽  
Vol 43 (2) ◽  
pp. 157-165 ◽  
Author(s):  
Oliver Zimmermann ◽  
Thomas P. Zwaka ◽  
Nikolaus Marx ◽  
Michael Torzewski ◽  
Andrea Bucher ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Growth Factor ◽  
Vascular Smooth Muscle ◽  
Smooth Muscle Cells ◽  
Vascular Smooth Muscle Cells ◽  
Growth Factor Receptor ◽  
Muscle Cells ◽  
Receptor Expression ◽  
Serum Starvation

Involvement of insulin-like growth factor 1 receptor transactivation in endothelin-1-induced signaling in vascular smooth muscle cells

2010 ◽  
Vol 88 (5) ◽  
pp. 501-509 ◽  
Author(s):  
Ali Bouallegue ◽  
George Vardatsikos ◽  
Ashok K. Srivastava
Keyword(s):  
Smooth Muscle ◽  
Growth Factor ◽  
Vascular Smooth Muscle ◽  
Smooth Muscle Cells ◽  
Vascular Smooth Muscle Cells ◽  
Growth Factor Receptor ◽  
Muscle Cells ◽  
Insulin Like Growth Factor ◽  
Endothelin 1 ◽  
Receptor Transactivation

Endothelin-1 (ET-1) is a potent vasoactive peptide that exerts hypertrophic, migratory, and mitogenic effects in vascular smooth muscle cells. ET-1-induced activation of several signaling events has been shown to mediate the cellular effects of ET-1. In the past several years, transactivation of growth factor receptor has gained much recognition in transducing the signaling responses of ET-1. Among various growth factor receptors studied, the involvement of epidermal growth factor receptor transactivation in triggering ET-1-induced responses has been studied in some detail. However, recent studies have implicated insulin-like growth factor 1 receptor transactivation in this process. There are also some suggestions for a role of the Src family of nonreceptor protein tyrosine kinases, such as c-Src, in transducing the signaling responses of vasoactive peptides. In this review, we will examine the contribution of both insulin-like growth factor 1 receptor and c-Src in mediating ET-1-induced signaling responses in vascular smooth muscle cells.

Expression of keratinocyte growth factor receptor (KGFR/FGFR2 IIIb) in vascular smooth muscle cells

2003 ◽  
Vol 53 (3) ◽  
pp. 127-132 ◽  
Author(s):  
Munehiko Onda ◽  
Zenya Naito ◽  
Ruojiao Wang ◽  
Takenori Fujii ◽  
Kiyoko Kawahara ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Growth Factor ◽  
Vascular Smooth Muscle ◽  
Smooth Muscle Cells ◽  
Vascular Smooth Muscle Cells ◽  
Keratinocyte Growth Factor ◽  
Growth Factor Receptor ◽  
Muscle Cells
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