Dietary Prevention of Coronary Heart Disease: The Lyon Diet Heart Study and After

2005 ◽  
pp. 103-114 ◽  
Author(s):  
Michel de Lorgeril ◽  
Patricia Salen
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Dietary Prevention ◽  
Lyon Diet Heart Study ◽  
Heart Study

scholarly journals Integrated genetic and epigenetic prediction of coronary heart disease in the Framingham Heart Study

PLoS ONE ◽  
2018 ◽  
Vol 13 (1) ◽  
pp. e0190549 ◽  
Author(s):  
Meeshanthini V. Dogan ◽  
Isabella M. Grumbach ◽  
Jacob J. Michaelson ◽  
Robert A. Philibert
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Framingham Heart Study ◽  
Heart Study

Dietary Prevention of Coronary Heart Disease in Women: The Finnish Mental Hospital Study

1983 ◽  
Vol 12 (1) ◽  
pp. 17-25 ◽  
Author(s):  
M. MIETTINEN ◽  
O. TURPEINEN ◽  
M. KARVONEN ◽  
M. PEKKARINEN ◽  
E. PAAVILAINEN ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Mental Hospital ◽  
Dietary Prevention ◽  
Hospital Study

scholarly journals Hand osteoarthritis in relation to mortality and incidence of cardiovascular disease: data from the Framingham Heart Study

2013 ◽  
Vol 74 (1) ◽  
pp. 74-81 ◽  
Author(s):  
Ida K Haugen ◽  
Vasan S Ramachandran ◽  
Devyani Misra ◽  
Tuhina Neogi ◽  
Jingbo Niu ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Lower Limb ◽  
Framingham Heart Study ◽  
Cardiovascular Events ◽  
Physical Inactivity ◽  
Hand Osteoarthritis ◽  
Coronary Insufficiency ◽  
Heart Study ◽  
Increased Risk

ObjectivesTo study whether hand osteoarthritis (OA) is associated with increased mortality and cardiovascular events in a large community based cohort (Framingham Heart Study) in which OA, mortality and cardiovascular events have been carefully assessed.MethodsWe examined whether symptomatic (≥1 joint(s) with radiographic OA and pain in the same joint) and radiographic hand OA (≥1 joint(s) with radiographic OA without pain) were associated with mortality and incident cardiovascular events (coronary heart disease, congestive heart failure and/or atherothrombotic brain infarction) using Cox proportional hazards models. In the adjusted models, we included possible confounding factors from baseline (eg, metabolic factors, medication use, smoking/alcohol). We also adjusted for the number of painful joints in the lower limb and physical inactivity.ResultsWe evaluated 1348 participants (53.8% women) with mean (SD) age of 62.2 (8.2) years, of whom 540 (40.1%) and 186 (13.8%) had radiographic and symptomatic hand OA, respectively. There was no association between hand OA and mortality. Although there was no significant relation to incident cardiovascular events overall or a relation of radiographic hand OA with events, we found a significant association between symptomatic hand OA and incident coronary heart disease (myocardial infarction/coronary insufficiency syndrome) (HR 2.26, 95% CI 1.22 to 4.18). The association remained after additional adjustment for pain in the lower limb or physical inactivity.ConclusionsSymptomatic hand OA, but not radiographic hand OA, was associated with an increased risk of coronary heart disease events. The results suggest an effect of pain, which may be a possible marker of inflammation.

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