Variability of the 3′ApoB Minisatellite Locus in Eastern Slavonic Populations

2005 ◽  
Vol 60 (1) ◽  
pp. 10-18 ◽  
Author(s):  
Dmitry A. Verbenko ◽  
A.N. Knjazev ◽  
A.I. Mikulich ◽  
E.K. Khusnutdinova ◽  
N.A. Bebyakova ◽  
...  
Keyword(s):  
Minisatellite Locus

Population genetic and family data for the human minisatellite locus D16S309 (MS205) in Germans

1996 ◽  
Vol 109 (4) ◽  
pp. 178-180 ◽  
Author(s):  
L. Henke ◽  
S. Cleef ◽  
M. Tahar ◽  
I. Kops ◽  
J. Henke
Keyword(s):  
Population Genetic ◽  
Family Data ◽  
Minisatellite Locus

Characterization of a highly unstable mouse minisatellite locus: Evidence for somatic mutation during early development

Genomics ◽  
1989 ◽  
Vol 5 (4) ◽  
pp. 844-856 ◽  
Author(s):  
Robert Kelly ◽  
Grahame Bulfield ◽  
Andrew Collick ◽  
Mark Gibbs ◽  
Alec J. Jeffreys
Keyword(s):  
Early Development ◽  
Somatic Mutation ◽  
Minisatellite Locus

Genetic variation at the ApoB 3? HVR minisatellite locus in the Mbenzele Pygmies from the Central African Republic

2000 ◽  
Vol 12 (5) ◽  
pp. 588-592 ◽  
Author(s):  
Giovanni Destro-Bisol ◽  
Michele Belledi ◽  
Cristian Capelli ◽  
Riccardo Maviglia ◽  
Gabriella Spedini
Keyword(s):  
Genetic Variation ◽  
Central African Republic ◽  
Minisatellite Locus

scholarly journals Mutation at the Human D1S80 Minisatellite Locus

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Kuppareddi Balamurugan ◽  
Martin L. Tracey ◽  
Uwe Heine ◽  
George C. Maha ◽  
George T. Duncan
Keyword(s):  
Mutation Rate ◽  
Chromosome 1 ◽  
Infinite Allele Model ◽  
Minisatellite Locus ◽  
Repeat Array ◽  
Mutation Model ◽  
Close Proximity ◽  
Stepwise Mutation ◽  
One Step ◽  
The One

Little is known about the general biology of minisatellites. The purpose of this study is to examine repeat mutations from the D1S80 minisatellite locus by sequence analysis to elucidate the mutational process at this locus. This is a highly polymorphic minisatellite locus, located in the subtelomeric region of chromosome 1. We have analyzed 90,000 human germline transmission events and found seven (7) mutations at this locus. The D1S80 alleles of the parentage trio, the child, mother, and the alleged father were sequenced and the origin of the mutation was determined. Using American Association of Blood Banks (AABB) guidelines, we found a male mutation rate of1.04×10-4and a female mutation rate of5.18×10-5with an overall mutation rate of approximately7.77×10-5. Also, in this study, we found that the identified mutations are in close proximity to the center of the repeat array rather than at the ends of the repeat array. Several studies have examined the mutational mechanisms of the minisatellites according to infinite allele model (IAM) and the one-step stepwise mutation model (SMM). In this study, we found that this locus fits into the one-step mutation model (SMM) mechanism in six out of seven instances similar to STR loci.

A highly polymorphic minisatellite locus (KBMS2) in bovine

1997 ◽  
Vol 28 (6) ◽  
pp. 456-457
Author(s):  
H Mannen ◽  
M Morimoto ◽  
M Yasui ◽  
A Atsuta ◽  
S Tsuji
Keyword(s):  
Minisatellite Locus

Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene minisatellite locus

1995 ◽  
Vol 9 (3) ◽  
pp. 284-292 ◽  
Author(s):  
S.T. Bennett ◽  
A.M. Lucassen ◽  
S.C.L. Gough ◽  
E.E. Powell ◽  
D.E. Undlien ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Tandem Repeat ◽  
Insulin Gene ◽  
Minisatellite Locus ◽  
Human Type ◽  
Human Type 1 Diabetes
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