Usefulness of in vitro 1H Magnetic Resonance Spectroscopy for the Characterization of Primary Brain Tumors: Report of Two Cases

2005 ◽  
Vol 83 (2-3) ◽  
pp. 122-127 ◽  
Author(s):  
Jean Sabatier ◽  
Olivier Robert ◽  
Marie-Bernadette Delisle ◽  
Myriam Malet-Martino
Keyword(s):  
Magnetic Resonance ◽  
Magnetic Resonance Spectroscopy ◽  
Brain Tumors ◽  
Resonance Spectroscopy ◽  
Primary Brain Tumors

Characterization of Choline Compounds with In Vitro 1H Magnetic Resonance Spectroscopy for the Discrimination of Primary Brain Tumors

1999 ◽  
Vol 34 (3) ◽  
pp. 230-235 ◽  
Author(s):  
JEAN SABATIER ◽  
VERONIQUE GILARD ◽  
MYRIAM MALET-MARTINO ◽  
JEAN-PHILIPPE RANJEVA ◽  
CORINNE TERRAL ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Magnetic Resonance Spectroscopy ◽  
Brain Tumors ◽  
Resonance Spectroscopy ◽  
1H Magnetic Resonance Spectroscopy ◽  
Primary Brain Tumors

scholarly journals Role of magnetic resonance spectroscopy in grading of primary brain tumors

2016 ◽  
Vol 47 (2) ◽  
pp. 577-584 ◽  
Author(s):  
Radwa Kamel Abdel Naser ◽  
Afaf Abdel Kader Hassan ◽  
Amr Mohamed Shabana ◽  
Nagham Nabil Omar
Keyword(s):  
Magnetic Resonance ◽  
Magnetic Resonance Spectroscopy ◽  
Brain Tumors ◽  
Resonance Spectroscopy ◽  
Primary Brain Tumors

31Phosphorus Magnetic Resonance Spectroscopy Characterization of Muscular Metabolic Anomalies in Patients with Malignant Hyperthermia 

1998 ◽  
Vol 88 (1) ◽  
pp. 96-107 ◽  
Author(s):  
David Bendahan ◽  
Genevieve Kozak-Ribbens ◽  
Laurence Rodet ◽  
Sylviane Confort-Gouny ◽  
Patrick J. Cozzone
Keyword(s):  
Magnetic Resonance ◽  
Magnetic Resonance Spectroscopy ◽  
Malignant Hyperthermia ◽  
False Negative ◽  
Resonance Spectroscopy ◽  
Diagnostic Strategy ◽  
Negative Results ◽  
Ph Decrease

Background Metabolic anomalies are known in skeletal muscles of patients with malignant hyperthermia (MH). Methods The authors used 31-phosphorus (31P) magnetic resonance spectroscopy (MRS) to compare metabolic changes of the finger flexor muscles recorded throughout two rest-exercise-recovery protocols (each including aerobic or ischemic exercise) in 26 healthy persons and in 13 MH-susceptible (MHS) persons who were unequivocally diagnosed by in vitro halothane-caffeine contracture tests on muscle biopsies. Results No abnormality was observed at rest and during recovery periods. A larger phosphocreatine decrease associated with an early drop of pH was noted during the first minute of both exercise periods for MHS patients compared with controls. The early pH decrease indicated a disorder affecting glycolytic activation, probably reflecting defects of Ca2+ cycling, and provided a sensitivity of 77% for MHS diagnosis. A diagnostic strategy based on the retrospective analysis of 19 selected MR parameters was developed. An MRS score, corresponding to the number of abnormal values among the 19 parameters, was calculated and provided sensitivity and specificity rates of 100%; that is, no false-positive or false-negative results were found. A prospective analysis of 10 new participants further confirmed these findings. Conclusions These results (1) further confirm that MH is associated with the preexistence of latent muscular disorders; (2) enhance the potential diagnostic capacity of MRS, although it should be tested prospectively on a larger group of participants; and (3) allows the characterization of several abnormal metabolic profiles, in persons with MHS, reflecting the recently described polymorphism of MH.

Localized In Vivo 1 H Magnetic Resonance Spectroscopy and In Vitro Analyses of Heterogeneous Brain Tumors

1995 ◽  
Vol 5 (3) ◽  
pp. 157-163 ◽  
Author(s):  
Linda Chang ◽  
Duncan McBride ◽  
Bruce L. Miller ◽  
Marsha Cornford ◽  
Ruth A. Booth ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Magnetic Resonance Spectroscopy ◽  
Brain Tumors ◽  
Resonance Spectroscopy
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