The Developmentally Regulated Expression of Menkes Protein ATP7A Suggests a Role in Axon Extension and Synaptogenesis

2005 ◽  
Vol 27 (5) ◽  
pp. 333-348 ◽  
Author(s):  
Rajaâ El Meskini ◽  
Laura B. Cline ◽  
Betty A. Eipper ◽  
Gabriele V. Ronnett
Keyword(s):  
Developmentally Regulated ◽  
Axon Extension ◽  
Regulated Expression ◽  
Menkes Protein

Developmentally regulated expression of a human "finger"-containing gene encoded by the 5' half of the ret transforming gene

1988 ◽  
Vol 8 (4) ◽  
pp. 1853-1856
Author(s):  
M Takahashi ◽  
Y Inaguma ◽  
H Hiai ◽  
F Hirose
Keyword(s):  
Human Gene ◽  
Mrna Levels ◽  
Nucleic Acid Binding ◽  
Developmentally Regulated ◽  
Unique Transcript ◽  
Binding Domains ◽  
Regulated Expression ◽  
Pachytene Spermatocytes ◽  
Human Finger ◽  
Transforming Gene

We isolated and sequenced a cDNA clone of the human gene encoded by the 5' half of the ret transforming gene. The nucleotide sequence indicates that it encodes a protein with "finger" structures which represent putative metal- and nucleic acid-binding domains. Transcription of this gene was detected at high levels in a variety of human and rodent tumor cell lines, mouse testis, and embryos. In addition, a unique transcript was observed in testis RNA. When the expression of the unique transcript was examined at different stages of spermatogenesis, a striking increase in mRNA levels accompanied progression from meiotic prophase pachytene spermatocytes to postmeiotic round spermatids. This finger-containing gene may thus function in male germ cell development.

scholarly journals NBP-45, a Novel Nucleosomal Binding Protein with a Tissue-specific and Developmentally Regulated Expression

2000 ◽  
Vol 275 (9) ◽  
pp. 6368-6374 ◽  
Author(s):  
Hitoshi Shirakawa ◽  
David Landsman ◽  
Yuri V. Postnikov ◽  
Michael Bustin
Keyword(s):  
Binding Protein ◽  
Developmentally Regulated ◽  
Tissue Specific ◽  
Regulated Expression

Expression of a duplicate Na,K-ATPase β1-isoform in the European eel (Anguilla anguilla)

2000 ◽  
Vol 279 (1) ◽  
pp. R222-R229 ◽  
Author(s):  
Christopher P. Cutler ◽  
Stephane Brezillon ◽  
Songul Bekir ◽  
Ian L. Sanders ◽  
Neil Hazon ◽  
...  
Keyword(s):  
Amino Acid ◽  
Functional Role ◽  
Intestinal Epithelial Cells ◽  
Anguilla Anguilla ◽  
European Eel ◽  
Mrna Levels ◽  
Intestinal Epithelial ◽  
Developmentally Regulated ◽  
Regulated Expression ◽  
Seawater Acclimation

Recent studies on teleost fish have suggested that their genomes have undergone ancient polyploidization events resulting in the duplication of the genome. A duplicate copy of the Na,K-ATPase β1-isoform (called β233) has been identified in the European eel ( Anguilla anguilla). The β233-isoform shares high levels of nucleotide (74.8%) and amino acid (69.9%) homology with the eel β1-subunit as well as other vertebrate β1-sequences. Compared with the widely expressed β1-isoform, expression of β233-mRNA is mainly restricted to epithelial tissues. Seawater acclimation induced increases in β233-mRNA levels in kidney, gill, and intestine of migratory “silver” but not the nonmigratory “yellow” adult eels, suggesting that the factors responsible for this upregulation are themselves developmentally regulated. Expression of a variably glycosylated 40- to 52-kDa β233-protein in both gill “chloride” and intestinal epithelial cells suggests that the β233-isoform of Na,K-ATPase may play an important functional role in the major osmoregulatory tissues of euryhaline fish such as the eel.

Genomic organisation and developmentally regulated expression of an apicomplexan aspartyl proteinase

Gene ◽  
2001 ◽  
Vol 262 (1-2) ◽  
pp. 129-136 ◽  
Author(s):  
Létitia Jean ◽  
Pierre Péry ◽  
Paul Dunn ◽  
Janene Bumstead ◽  
Karen Billington ◽  
...  
Keyword(s):  
Developmentally Regulated ◽  
Regulated Expression ◽  
Genomic Organisation

Developmentally regulated expression of VGLUT3 during early post-natal life

2005 ◽  
Vol 49 (6) ◽  
pp. 901-911 ◽  
Author(s):  
Christelle Gras ◽  
Jacqueline Vinatier ◽  
Bénédicte Amilhon ◽  
Aline Guerci ◽  
Christo Christov ◽  
...  
Keyword(s):  
Developmentally Regulated ◽  
Regulated Expression
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