Pharmacological and Functional Characterization of Endothelin Receptors in Bovine Trabecular Meshwork and Ciliary Muscle

2005 ◽  
Vol 37 (4) ◽  
pp. 179-187 ◽  
Author(s):  
Lars Choritz ◽  
Rita Rosenthal ◽  
Michael Fromm ◽  
Michael H. Foerster ◽  
Hagen Thieme
Keyword(s):  
Trabecular Meshwork ◽  
Functional Characterization ◽  
Ciliary Muscle ◽  
Endothelin Receptors

Functional characterization of adult human trabecular meshwork stem cells

2021 ◽  
pp. 112709
Author(s):  
Yogapriya Sundaresan ◽  
Krishnadas Subbiah Ramasamy ◽  
Muthukkaruppan Veerappan ◽  
Gowri Priya Chidambaranathan
Keyword(s):  
Stem Cells ◽  
Trabecular Meshwork ◽  
Functional Characterization ◽  
Adult Human

scholarly journals Characterization of Cytoskeleton-Enriched Protein Fraction of the Trabecular Meshwork and Ciliary Muscle Cells

2010 ◽  
Vol 51 (12) ◽  
pp. 6461 ◽  
Author(s):  
Toshihiro Inoue ◽  
Paula Pecen ◽  
Rupalatha Maddala ◽  
Nikolai P. Skiba ◽  
Padmanabhan P. Pattabiraman ◽  
...  
Keyword(s):  
Trabecular Meshwork ◽  
Protein Fraction ◽  
Muscle Cells ◽  
Ciliary Muscle

Functional characterization of endothelin receptors in hypertensive resistance vessels

1999 ◽  
Vol 17 (1) ◽  
pp. 45-52 ◽  
Author(s):  
Monica Montagnani ◽  
Maria A. Potenza ◽  
Rosanna Rinaldi ◽  
Gianfranco Mansi ◽  
Carmela Nacci ◽  
...  
Keyword(s):  
Functional Characterization ◽  
Endothelin Receptors ◽  
Resistance Vessels

Identification and functional characterization of ClC-2 chloride channels in trabecular meshwork cells

2006 ◽  
Vol 83 (4) ◽  
pp. 877-889 ◽  
Author(s):  
Núria Comes ◽  
Elena Abad ◽  
Miguel Morales ◽  
Teresa Borrás ◽  
Arcadi Gual ◽  
...  
Keyword(s):  
Trabecular Meshwork ◽  
Chloride Channels ◽  
Functional Characterization ◽  
Trabecular Meshwork Cells

Functional characterization of human brown adipose tissue metabolism

2020 ◽  
Vol 477 (7) ◽  
pp. 1261-1286 ◽  
Author(s):  
Marie Anne Richard ◽  
Hannah Pallubinsky ◽  
Denis P. Blondin
Keyword(s):  
Adipose Tissue ◽  
Brown Adipose Tissue ◽  
Functional Characterization ◽  
Human Infants ◽  
Positron Emission ◽  
Brown Adipose ◽  
Treatment Of Obesity ◽  
And Function

Brown adipose tissue (BAT) has long been described according to its histological features as a multilocular, lipid-containing tissue, light brown in color, that is also responsive to the cold and found especially in hibernating mammals and human infants. Its presence in both hibernators and human infants, combined with its function as a heat-generating organ, raised many questions about its role in humans. Early characterizations of the tissue in humans focused on its progressive atrophy with age and its apparent importance for cold-exposed workers. However, the use of positron emission tomography (PET) with the glucose tracer [18F]fluorodeoxyglucose ([18F]FDG) made it possible to begin characterizing the possible function of BAT in adult humans, and whether it could play a role in the prevention or treatment of obesity and type 2 diabetes (T2D). This review focuses on the in vivo functional characterization of human BAT, the methodological approaches applied to examine these features and addresses critical gaps that remain in moving the field forward. Specifically, we describe the anatomical and biomolecular features of human BAT, the modalities and applications of non-invasive tools such as PET and magnetic resonance imaging coupled with spectroscopy (MRI/MRS) to study BAT morphology and function in vivo, and finally describe the functional characteristics of human BAT that have only been possible through the development and application of such tools.

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