‘Successful’ Chemo- and Radiotherapy prior to Radical Cystectomy Does Not Necessarily Correlate with Clinical Course in Small Cell Carcinoma of the Bladder

2005 ◽  
Vol 74 (3) ◽  
pp. 286-288 ◽  
Author(s):  
Takehiro Sejima ◽  
Ikuo Miyagawa
Keyword(s):  
Cell Carcinoma ◽  
Radical Cystectomy ◽  
Small Cell Carcinoma ◽  
Clinical Course ◽  
Small Cell ◽  
Carcinoma Of The Bladder

scholarly journals A Case of Primary Small-Cell Carcinoma of the Bladder

2016 ◽  
Vol 9 (3) ◽  
pp. 574-579 ◽  
Author(s):  
Ashita Ono ◽  
Yosuke Hirasawa ◽  
Mitsumasa Yamashina ◽  
Naoto Kaburagi ◽  
Takashi Mima ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Urothelial Carcinoma ◽  
Cell Carcinoma ◽  
Radical Cystectomy ◽  
Small Cell Carcinoma ◽  
Distant Metastasis ◽  
Small Cell ◽  
Common Type ◽  
Cell Of Origin ◽  
Carcinoma Of The Bladder

Primary small-cell carcinoma arising from the bladder (SmCCB) is uncommon. It differs from urothelial carcinoma (UC), the most common type of bladder cancer, with respect to its cell of origin, biology, and prognosis. Biologically, prostatic SmCCB is much more aggressive than UC, and the prognosis for cases with distant metastasis is especially poor. We report here a case of primary SmCCB (cT3bN1M0) treated with radical cystectomy.

Small Cell Carcinoma of the Urinary Bladder. Report of two Cases and Review of the Literature

1992 ◽  
Vol 78 (6) ◽  
pp. 409-413 ◽  
Author(s):  
Maurizio Amichetti ◽  
Sebastiana Boi ◽  
Gianni Fellin ◽  
Sergio Maluta ◽  
Paolo Dalla Palma ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Urinary Tract ◽  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Clinical Course ◽  
Neuroendocrine Differentiation ◽  
Small Cell ◽  
Review Of The Literature ◽  
Progression Of Disease ◽  
Carcinoma Of The Bladder

Undifferentiated small cell carcinoma of the bladder is a rare but aggressive subset of urinary tract neoplasms. Analogous to small-cell carcinoma of the lung, this tumor frequently exhibits neuroendocrine differentiation. We report the 92nd and 93rd case of small cell carcinoma of the bladder reported in the literature with characteristic cytologic, histologic, histochemical, and ultrastructural features. The patients were treated initially with chemotherapy, but after a brief clinical course died for progression of disease and for myocardial infarction, respectively. The pathologic and clinical features and therapeutic options of the cases described in the literature are reviewed.

Long-term results of radical cystectomy and role of adjuvant chemotherapy for small cell carcinoma of the bladder

2015 ◽  
Vol 22 (6) ◽  
pp. 549-554 ◽  
Author(s):  
Dharam Kaushik ◽  
Igor Frank ◽  
Stephen A Boorjian ◽  
John C Cheville ◽  
Manuel S Eisenberg ◽  
...  
Keyword(s):  
Adjuvant Chemotherapy ◽  
Cell Carcinoma ◽  
Radical Cystectomy ◽  
Small Cell Carcinoma ◽  
Small Cell ◽  
Long Term Results ◽  
Carcinoma Of The Bladder

Long-Term Outcomes of Organ Preservation in Patients with Small Cell Carcinoma of the Bladder

2015 ◽  
Vol 94 (4) ◽  
pp. 401-405 ◽  
Author(s):  
Jairam R. Eswara ◽  
Niall M. Heney ◽  
Chin-Lee Wu ◽  
W. Scott McDougal
Keyword(s):  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Metastatic Disease ◽  
Advanced Disease ◽  
Chemical Exposure ◽  
Small Cell ◽  
Cancer Specific Survival ◽  
Entire Cohort ◽  
Aggressive Disease ◽  
Carcinoma Of The Bladder

Background: Small cell carcinoma of the bladder is an uncommon but clinically aggressive disease. There is no standard surgical or medical management for the disease. Methods: Between 1995 and 2009, 28 patients underwent transurethral resection (TUR) and/or cystectomy, chemotherapy, and/or radiation for small cell carcinoma of the bladder at our institution. Results: The median follow-up for survivors was 34 months. Patients presented most often with muscle-invasive disease (T2-4 - 89%), and 21% had lymph node/distant metastases. Tobacco use and chemical exposure were noted in 64 and 4% of patients, respectively. Patients with T1-2N0M0 had a median survival of 22 months compared to 8 months for those with more advanced disease (p = 0.03). Patients with T3-4 or nodal/metastatic disease who were given chemotherapy had an improved survival compared to those with T3-4 or nodal/metastatic disease who did not undergo chemotherapy (13 vs. 4 months, p = 0.005). The median time to recurrence of the entire cohort was 8 months, overall and cancer-specific survival was 14 months, and 5-year survival was 11%. Conclusions: Small cell carcinoma of the bladder is an aggressive disease with poor outcomes. Patients with T1-2N0M0 disease survived longer than those with advanced disease. Patients with T3-4 or nodal/metastatic disease had improved survival with chemotherapy.

Locoregional Small Cell Carcinoma of the Bladder: Clinical Characteristics and Treatment Patterns

2014 ◽  
Vol 191 (2) ◽  
pp. 329-334 ◽  
Author(s):  
Sanjay G. Patel ◽  
C.J. Stimson ◽  
Harras B. Zaid ◽  
Matthew J. Resnick ◽  
Michael S. Cookson ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Clinical Characteristics ◽  
Treatment Patterns ◽  
Small Cell ◽  
Carcinoma Of The Bladder

SMALL CELL CARCINOMA OF THE BLADDER MIMICKING A GYNECOLOGICAL TUMOR

2001 ◽  
Vol 165 (1) ◽  
pp. 186-187 ◽  
Author(s):  
LI-JEN WANG ◽  
YON-CHEONG WONG ◽  
YANG-JEN CHIANG ◽  
CHI-JEN CHEN
Keyword(s):  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Small Cell ◽  
Gynecological Tumor ◽  
Carcinoma Of The Bladder

scholarly journals First Case of Cellular Cannibalism in Small-Cell Carcinoma of the Bladder Detected in Peripheral Blood

2019 ◽  
Vol 39 (4) ◽  
pp. 400-402
Author(s):  
Hyein Kang ◽  
Do-Hoon Kim ◽  
Wonmok Lee ◽  
Jungsook Ha ◽  
Namhee Ryoo ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Peripheral Blood ◽  
Small Cell ◽  
First Case ◽  
Carcinoma Of The Bladder

Small Cell Carcinoma of the Gallbladder: Clinical Course and Response to Chemotherapy

1992 ◽  
Vol 78 (3) ◽  
pp. 207-210 ◽  
Author(s):  
Ilan-Gil Ron ◽  
Nelly Wigler ◽  
Bianca Ilie ◽  
Samario Chaitchik
Keyword(s):  
Partial Response ◽  
Gall Bladder ◽  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Clinical Course ◽  
Small Cell ◽  
Rare Tumor ◽  
Carcinoma Of The Gallbladder ◽  
Response To Chemotherapy ◽  
Oat Cell Carcinoma

Small cell carcinoma of the gall bladder is a rare tumor. The neoplasm is highly lethal, metastasizes early, and may cause death shortly after diagnosis. An oat cell carcinoma of the gallbladder metastatic to the liver and adjacent lymph nodes is described in a 60-year-old male. Partial cholecystectomy was performed followed by aggressive chemotherapy with etoposide and cisplatinum. An 80 % reduction in the size of the unexcised tumor was noted over a period of 6 months. The partial response and the relatively long survival of the patient suggest the use of the above protocol for these rare cases.

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