Improvement of Gastric Motility with Gastric Electrical Stimulation in STZ-Induced Diabetic Rats

Digestion ◽  
2004 ◽  
Vol 70 (3) ◽  
pp. 159-166 ◽  
Author(s):  
Jinsong Liu ◽  
Xian Qiao ◽  
Maria-Adelaide Micci ◽  
Pankaj J. Pasricha ◽  
J.D.Z. Chen
Keyword(s):  
Electrical Stimulation ◽  
Gastric Motility ◽  
Diabetic Rats ◽  
Gastric Electrical Stimulation

scholarly journals Synchronized Dual Pulse Gastric Electrical Stimulation Induces Activation of Enteric Glial Cells in Rats with Diabetic Gastroparesis

2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
Wei Yang ◽  
Nian Wang ◽  
Xue Shi ◽  
Jie Chen
Keyword(s):  
Electrical Stimulation ◽  
Gastric Emptying ◽  
Gastric Motility ◽  
Diabetic Rats ◽  
Slow Waves ◽  
Gastric Electrical Stimulation ◽  
Control Group ◽  
Gastric Slow Waves ◽  
Enteric Glial Cells ◽  
Before And After

Objective.The aims of this study were to investigate the effects of synchronized dual pulse gastric electrical stimulation (SGES) on gastric motility in different periods for diabetic rats and try to explore the possible mechanisms of the effects.Methods.Forty-six rats were used in the study. Gastric slow waves were recorded at baseline, 7–14-day diabetes and 56–63-day diabetes before and after stimulation and the age-matched control groups. SGES-60 mins and SGES-7 days (60 mins/day) were performed to test the effects on gastric motility and to evaluate glial marker S100B expression in stomach.Results.(1) Gastric emptying was accelerated in 7–14-day diabetes and delayed in 56–63-day diabetes. (2) The S100B expression in 56–63-day diabetes decreased and the ultrastructure changed. (3) The age-associated loss of EGC was observed in 56–63-day control group. (4) SGES was able to not only accelerate gastric emptying but also normalize gastric slow waves. (5) The S100B expression increased after SGES and the ultrastructure of EGC was partially restored. The effect of SGES-7 days was superior to SGES-60 mins.Conclusions.Delayed gastric emptying due to the growth of age may be related to the EGC inactivation. The effects of the SGES on gastric motility may be associated with EGC activation.

scholarly journals Effect of two-channel gastric electrical stimulation with trains of pulses on gastric motility

2009 ◽  
Vol 15 (19) ◽  
pp. 2406
Author(s):  
Bin Yang ◽  
Xiao-Hua Hou ◽  
Geng-Qing Song ◽  
Jin-Song Liu ◽  
Jiande DZ Chen
Keyword(s):  
Electrical Stimulation ◽  
Gastric Motility ◽  
Gastric Electrical Stimulation

Gastric Electrical Stimulation Optimized to Inhibit Gastric Motility Reduces Food Intake in Dogs

2014 ◽  
Vol 25 (6) ◽  
pp. 1047-1055 ◽  
Author(s):  
Geng-Qing Song ◽  
Hongbing Zhu ◽  
Yong Lei ◽  
Charlene Yuan ◽  
Warren Starkebaum ◽  
...  
Keyword(s):  
Electrical Stimulation ◽  
Food Intake ◽  
Gastric Motility ◽  
Gastric Electrical Stimulation

871 Gastric Electrical Stimulation with Wider Pulses Inhibits Food Intake and Gastric Motility in Dogs

2009 ◽  
Vol 136 (5) ◽  
pp. A-134 ◽  
Author(s):  
Geng-Qing Song ◽  
Hongbing Zhu ◽  
Yong Lei ◽  
Charlene Yuan ◽  
Warren Starkebaum ◽  
...  
Keyword(s):  
Electrical Stimulation ◽  
Food Intake ◽  
Gastric Motility ◽  
Gastric Electrical Stimulation

Comparative gastric motility study of EnterraTM Therapy and neural gastric electrical stimulation in an acute canine model

2010 ◽  
Vol 23 (3) ◽  
pp. 271-e122 ◽  
Author(s):  
A. Arriagada ◽  
A. S. Jurkov ◽  
E. Neshev ◽  
G. Muench ◽  
M. P. Mintchev ◽  
...  
Keyword(s):  
Electrical Stimulation ◽  
Gastric Motility ◽  
Canine Model ◽  
Gastric Electrical Stimulation
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