scholarly journals Change in Parameters before and after Alpha-1-Blocker Therapy for Men with Lower Urinary Tract Symptoms Using Color Doppler Ultrasound Urodynamics: Possible Application for Prediction of Clinical Outcome

2004 ◽  
Vol 73 (3) ◽  
pp. 252-257 ◽  
Author(s):  
Yuichi Watanabe ◽  
Teruhiko Yokoyama ◽  
Hideo Ozawa ◽  
Jun Nishiguchi ◽  
Hiroyuki Nose ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Clinical Outcome ◽  
Lower Urinary Tract Symptoms ◽  
Lower Urinary Tract ◽  
Color Doppler ◽  
Color Doppler Ultrasound ◽  
Blocker Therapy ◽  
Urinary Tract Symptoms ◽  
Before And After ◽  
Lower Urinary

scholarly journals Does Pharmacological Treatment Reduce the Incidence of Lower Urinary Tract Symptoms (LUTS) after Transobturator Sling?

2019 ◽  
Vol 2019 ◽  
pp. 1-7 ◽  
Author(s):  
Tomasz Rechberger ◽  
Andrzej Wrobel ◽  
Alicja Zietek ◽  
Ewa Rechberger ◽  
Beata Kulik-Rechberger ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Lower Urinary Tract Symptoms ◽  
Pharmacological Treatment ◽  
Lower Urinary Tract ◽  
Midurethral Sling ◽  
Additional Treatment ◽  
Urinary Tract Symptoms ◽  
Before And After ◽  
Sling Placement ◽  
Lower Urinary

Aim. Lower urinary tract symptoms (LUTS) frequently affect patients immediately after midurethral sling (MUS) placement. The objective of the study was to assess if solifenacin or mirabegron decreases incidence of LUTS in women who underwent transobturator MUS. Methods. A prospective randomized trial was conducted on patients undergoing ambulatory transobturator midurethral sling due to stress urinary incontinence (SUI). All participants were questioned before and after surgery for occurrence of bothersome LUTS. A total of 328 patients who underwent transobturator MUS were randomly assigned to one of three groups: prophylaxis with 10 mg of solifenacin, prophylaxis with 50 mg of mirabegron, or without any additional treatment. LUTS evolution and efficacy of solifenacin and mirabegron were analyzed based on results of assessments made during follow-up visits at 1 and 6 weeks after surgery. Comparison of the prevalence of LUTS was done using chi2 test. Results. Prevalence of urgency and frequency episodes increased notably 1 week after sling placement and then came down to baseline levels. Solifenacin and mirabegron significantly reduced the incidence of urgency after 1 week, but after 6 weeks the beneficial effect was observed only in case of solifenacin. Treatment with mirabegron reduced the percentage of patients suffering from frequency after 6 weeks. Although prevalence of nocturia did not raise after sling placement, both treatments significantly reduced the incidence of this complaint after 6 weeks. Pharmacological treatment did not modulate the course of hesitancy and terminal dribbling. Conclusions. Treatment with solifenacin or mirabegron may significantly reduce the incidence of undesired LUTS after MUS.

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