Quality of Life in the Very Elderly after Cardiac Surgery: A Comparison of SF-36 between Long-Term Survivors and an Age-Matched Population

Gerontology ◽  
2004 ◽  
Vol 50 (6) ◽  
pp. 407-410 ◽  
Author(s):  
Johan Sjögren ◽  
Lars I. Thulin
Keyword(s):  
Quality Of Life ◽  
Cardiac Surgery ◽  
Very Elderly ◽  
Sf 36 ◽  
Long Term Survivors

Functional status and quality of life in long-term survivors of cardiac arrest after cardiac surgery

2001 ◽  
Vol 29 (7) ◽  
pp. 1408-1411 ◽  
Author(s):  
Ioanna Dimopoulou ◽  
Anastasia Anthi ◽  
Alkis Michalis ◽  
George E. Tzelepis
Keyword(s):  
Quality Of Life ◽  
Cardiac Arrest ◽  
Cardiac Surgery ◽  
Functional Status ◽  
Long Term Survivors

Quality of Life in Survivors of Childhood and Adolescent Acute Myelogenous Leukemia (AML) Does Not Differ by Treatment (Bone Marrow Transplant (BMT) vs. Chemotherapy). A Report from the Children’s Oncology Group (COG).

Blood ◽  
2005 ◽  
Vol 106 (11) ◽  
pp. 701-701
Author(s):  
H. Stacy Nicholson ◽  
Tianni Zhou ◽  
Zhengjia Chen ◽  
Kellie Moran ◽  
Charles Sklar ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Bone Marrow ◽  
Summary Score ◽  
Myelogenous Leukemia ◽  
Age At Diagnosis ◽  
P Value ◽  
Sf 36 ◽  
Long Term Survivors

Abstract Childhood and adolescent AML requires intensive therapy. Beginning in 1979, the Childrens Cancer Group (CCG) randomized patients with newly-diagnosed AML to allogeneic bone marrow transplantation (alloBMT) based solely on the availability of an HLA-identical sibling donor. Two decades of successive CCG trials using a similar design have shown a significant survival advantage for alloBMT. To determine whether BMT was associated with a diminished quality of life (QOL) in long-term survivors compared to those who had been treated with chemotherapy alone (chemo), we conducted a cross-sectional telephone survey study of AML survivors. To be eligible, survivors must have been enrolled on a CCG AML study (beginning in 1979), have survived at least five years, and reside in the US or Canada. QOL was measured using the Medical Outcomes Study Short Form 36 (SF-36) and the Child Health Questionnaire (CHQ). 206 survivors completed the study, including 124 treated with chemo, 54 treated with alloBMT and 28 treated with autologous BMT (autoBMT). Median age at diagnosis was 3 years (range, 0–20), median age at survey was 19 years (range 8–39) and median time from diagnosis was 13.4 years. 48% were male, and 87% were white. QOL summary scores for the 82 survivors treated with BMT did not differ from those of the 124 treated with chemo (see table). Also, the adjusted summary scores did not differ by treatment after adjustment for other factors, such as age at diagnosis, race, gender, relapse, etc. None of the physical or mental SF-36 or CHQ subscale domains significantly differed by treatment, although physical subscale domains trended to be better in the chemo group. Multivariate analyses found that females had significantly lower physical and mental scores, that relapse significantly diminished the physical summary score, and that age at diagnosis was positively and significantly associated with higher mental summary score. Our data suggest that survivors of childhood and adolescent AML have similar overall QOL scores, regardless of whether they were treated with BMT or chemo. In addition, the QOL scores in most physical and mental health domains were high, suggesting that AML survivors as a group enjoyed good QOL. These data suggest that QOL in long-term survivors is not diminished by BMT and that the primary concern in assigning treatment remains survival. QOL Summary Scores Treatment Physical Score Mental Score Mean 95% CI p-value Mean 95% CI p-value All 49.3 (48.0,50,7) 49.9 (48.4,51.3) BMT (n=82) 49.0 (46.8,51.1) 0.68 51.3 (49.0,53.6) 0.11 Chemo (n=124) 49.6 (47.8,51.3) 48.9 (47.0,50.8)

Long-Term Survival and Quality of Life Justify Cardiac Surgery in the Very Elderly Patient

2011 ◽  
Vol 92 (3) ◽  
pp. 851-857 ◽  
Author(s):  
Ravi K. Ghanta ◽  
Prem S. Shekar ◽  
Siobhan McGurk ◽  
Donna M. Rosborough ◽  
Sary F. Aranki
Keyword(s):  
Quality Of Life ◽  
Elderly Patient ◽  
Cardiac Surgery ◽  
Very Elderly ◽  
Term Survival ◽  
Long Term Survival

Quality of Life of Long-Term Survivors of Non–Small-Cell Lung Cancer

2002 ◽  
Vol 20 (13) ◽  
pp. 2920-2929 ◽  
Author(s):  
Linda Sarna ◽  
Geraldine Padilla ◽  
Carmack Holmes ◽  
Donald Tashkin ◽  
Mary Lynn Brecht ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Lung Cancer ◽  
Pulmonary Function ◽  
Small Cell ◽  
Living Alone ◽  
Small Cell Lung ◽  
Sf 36 ◽  
Long Term Survivors

PURPOSE: To describe the quality of life (QOL) among survivors of non–small-cell lung cancer (NSCLC).PATIENTS AND METHODS: One hundred forty-two 5-year minimum self-reported disease-free survivors of NSCLC completed QOL instruments (QOL-Survivor and Medical Outcomes Study 36-Item Short Form [SF-36]) and assessments of emotional distress (Center for Epidemiologic Studies Depression Scale [CES-D]), comorbid disease, and tobacco use. Pulmonary function was assessed with a hand-held spirometer. Multivariate regression methods were used on total QOL-Survivor scores and physical (PC) and mental (MC) component scores of the SF-36.RESULTS: The majority (71%) of survivors described themselves as hopeful, and 50% viewed the cancer experience as contributing to positive life changes (QOL-Survivor). Comorbidity was common (60% ≥ one condition); 22% had distressed mood (CES-D ≥ 16). Most were former smokers (76%); 13% continued to smoke. Half had moderate/severe pulmonary distress (forced expired volume in 1 second [FEV1] < 70% of predicted). Regression models including the set of variables (age, sex, living alone, education, smoking status, pulmonary function category, distressed mood, time since diagnosis, and comorbidity) accounted for 37%, 48%, and 29% in the QOL-total, MC, and PC scores, respectively. Primary predictors of lower QOL scores were white ethnicity and distressed mood (CES-D ≥ 16) (34% of the variance explained). The primary predictor of lower MC scores was distressed mood (R2= 0.45). Lower PC scores were associated with older age, living alone, FEV1less than 70% of predicted, distressed mood, time since diagnosis, and more comorbid diseases (R2= 0.28).CONCLUSION: These findings provide the first description of the QOL of long-term survivors of lung cancer. Risk factors for poorer QOL are strongly linked to distressed mood, which is a potential target for intervention.

Quality of Life in Breast and Colon Cancer Long-term Survivors: An Assessment with the Eortc Qlq-c30 and Sf-36 Questionnaires

2002 ◽  
Vol 88 (2) ◽  
pp. 110-116 ◽  
Author(s):  
Paola Mosconi ◽  
Giovanni Apolone ◽  
Sandro Barni ◽  
Simona Secondino ◽  
Alberto Sbanotto ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Colon Cancer ◽  
Sf 36 ◽  
Eortc Qlq C30 ◽  
Eortc Qlq ◽  
Long Term Survivors

scholarly journals Long-term quality of life and posttraumatic stress following elective cardiac surgery: preliminary findings of a 5-year follow-up study

2019 ◽  
Vol 26 (1) ◽  
pp. 87-92 ◽  
Author(s):  
Daiva Gražulytė ◽  
Evaldas Kazlauskas ◽  
Ieva Norkienė ◽  
Smiltė Kolevinskaitė ◽  
Greta Kezytė ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cardiac Surgery ◽  
Posttraumatic Stress ◽  
Well Being ◽  
Postoperative Hospital Stay ◽  
Elective Cardiac Surgery ◽  
Sf 36

Background. Heart surgery is a major stressful event that can have a significant negative effect on patients’ quality of life (QoL) and may cause long-term posttraumatic stress reactions. The aim of this pilot study was to estimate the longitudinal change and predictors of health-related quality of life (HRQOL) dynamics and identify factors associated with PTS at 5-year follow-up (T2) after elective cardiac surgery and associations with pre-surgery (T1) QoL. Materials and methods. Single-centre prospective study was conducted after Regional Bioethics Committee approval. Adult consecutive patients undergoing elective cardiac surgery were included. HRQOL was measured using the Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36) questionnaire before (T1) and 5-years after (T2) cardiac surgery. Posttraumatic stress was assessed using the International Trauma Questionnaire. Results. The pilot study revealed a significant positive change at 5-year follow-up in several domains of SF-36: physical functioning (PF), energy/fatigue (E/F), and social functioning (SF). Prolonged postoperative hospital stay was associated with change in SF (p < 0.01), E/F (p < 0.05) and emotional well-being (p < 0.05). The percentage of patients that had the posttraumatic stress disor. der (PTSD) at T2 was 12.2%. Posttraumatic stress symptoms were associated with longer hospitalization after surgery (p < 0.01). Conclusions. HRQOL improved from baseline to five years postoperatively. Patients with lower preoperative HRQOL scores tended to have a more significant improvement of HRQOL five years after surgery. A prolonged postoperative hospital stay had a negative impact on postoperative social functioning, energy/fatigue, and emotional well-being. Increased levels of PTSD were found in cardiac surgery patients following five years after the surgery.

Side Effects and Cancer-Related Stress Determine Quality of Life in Long-Term Survivors of Testicular Cancer

2005 ◽  
Vol 23 (13) ◽  
pp. 3061-3068 ◽  
Author(s):  
Arnstein Mykletun ◽  
Alv A. Dahl ◽  
Carl Fredrik Haaland ◽  
Roy Bremnes ◽  
Olav Dahl ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Side Effects ◽  
Testicular Cancer ◽  
Treatment Modality ◽  
Treatment Modalities ◽  
Sf 36 ◽  
Related Stress ◽  
Long Term Survivors

Purpose The prevalence of long-term survivors after treatment for testicular cancer (TC) is increasing, and most studies display normal or only slightly reduced quality of life (QOL) in TC survivors (TCSs). Impaired QOL is claimed to be associated with treatment modality and its side effects, although most studies in this field can be criticized for various methodologic shortcomings. We wanted to examine variation in long-term QOL in TCSs in relation to TC treatment modality, side effects, and TC-related stress in a large population. Patients and Methods QOL, side effects, and TC-related stress were self-rated by a questionnaire at a mean of 11 years of follow-up in 1,409 TCSs treated from 1980 to 1994. Norm data was obtained from 2,678 males who were representative of the general population. QOL was measured with the Short Form-36 (SF-36), and TC-related stress was measured with the Impact of Event Scale. Results There were no clinically relevant differences in QOL between TCSs and age-adjusted norm data, although there was a slightly lowered SF-36 Physical Component Summary Score in TCSs. Variation of QOL in TCSs was related to self-reported side effects and TC-related stress but not to TC treatment modality. A significant association was found between side effects and TC-related stress. Conclusion TCSs do not suffer long term from reduced QOL, and only minor differences in QOL were found between different treatment modalities. TCSs who report more side effects or TC-related stress have increased risk for reduced QOL, but these associations are not explained by TC treatment modalities. Further QOL research in this area should explore vulnerability factors for side effects and TC-related stress.

scholarly journals Functional status and quality of life (QoL) in long-term survivors of cardiac arrest after cardiac surgery

Critical Care ◽  
10.1186/cc933 ◽  
2000 ◽  
Vol 4 (Suppl 1) ◽  
pp. P214
Author(s):  
A Anthi ◽  
I Dimopoulou ◽  
A Michalis ◽  
GE Tzelepis
Keyword(s):  
Quality Of Life ◽  
Cardiac Arrest ◽  
Cardiac Surgery ◽  
Functional Status ◽  
Long Term Survivors
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