Riboflavin Deficiency Induces Ocular Surface Damage

2004 ◽  
Vol 36 (3) ◽  
pp. 156-165 ◽  
Author(s):  
Yumiko Takami ◽  
Huaqing Gong ◽  
Tsugio Amemiya
Keyword(s):  
Ocular Surface ◽  
Surface Damage ◽  
Riboflavin Deficiency

Reduction of Ocular Surface Damage and Bacterial Survival Using 0.05% Povidone-Iodine Ocular Surface Irrigation before Cataract Surgery

2019 ◽  
Vol 62 (3) ◽  
pp. 166-172 ◽  
Author(s):  
Fang Fan ◽  
Zhihua Zhao ◽  
Xiaobin Zhao ◽  
Qingmin Ma ◽  
Kejun Li ◽  
...  
Keyword(s):  
Cataract Surgery ◽  
Ocular Surface ◽  
Povidone Iodine ◽  
Surface Damage ◽  
Bacterial Survival ◽  
Surface Irrigation

scholarly journals In Vivo Confocal Microscopic Evaluation of Corneal Langerhans Cells in Dry Eye Patients§

2014 ◽  
Vol 8 (1) ◽  
pp. 51-59 ◽  
Author(s):  
Federica Machetta ◽  
Antonio M Fea ◽  
Alessandro G Actis ◽  
Ugo de Sanctis ◽  
Paola Dalmasso ◽  
...  
Keyword(s):  
Confocal Microscopy ◽  
Dry Eye ◽  
Ocular Surface ◽  
Tear Film ◽  
Surface Damage ◽  
Nerve Plexus ◽  
Sjogren Syndrome ◽  
Central Cornea ◽  
Eye Symptoms ◽  
Dry Eye Symptoms

Purpose. To assess inflammatory involvement of cornea in dry eye by means of confocal microscopy, evaluating the presence and distribution of Langherans cells (LCs). Methods: 98 eyes of 49 subjects were enrolled: 18 subjects affected by Sjögren Syndrome Dry Eye (SSDE), 17 with Non-Sjögren Syndrome Dry Eye (NSSDE), 14 healthy volunteeers. Dry eye symptoms, tear film, ocular surface damage and corneal confocal microscopy were analized. Results: A significant increase of LCs density was observed at sub-basal nerve plexus (SSDE = 79 cells/mm2 and NDE = 22 cells/mm2; p = 0,0031) and sub-epithelial nerve plexus (SSDE = 38 cells/mm2 and NDE = 3 cells/mm2; p = 0,0169) in central cornea of SSDE group. An increased number of LCs from the center to the periphery of the cornea was observed, significant only in healthy volunteers group. In dry eye patients there was an increase in LCs density in both peripheral and central cornea with a significant difference between NDE (14,66 cells/mm2) and SSDE (56,66 cells/mm2) only in central cornea (p = 0,0028). In SSDE group, mean density of LCs in central cornea results also superior to NSSDE group (29,33 cells/mm2). There was no correlation between LCs density and dry eye symptoms, tear film deficiency and ocular surface damage. Conclusion: This study demonstrates the activation of an inflammatory and immunological reaction in cornea of NSSDE and SSDE patients. Confocal microscopy can be an important diagnostic tool in evaluation and follow-up of dry eye disease.

scholarly journals Zdravljenje glavkoma in suho oko

2016 ◽  
Vol 85 (4) ◽  
Author(s):  
Barbara Cvenkel
Keyword(s):  
Ocular Surface ◽  
Clinical Signs ◽  
Tear Film ◽  
Signs And Symptoms ◽  
Surface Damage ◽  
Eye Drops ◽  
Film Instability ◽  
Asymptomatic Patients

Patients with glaucoma have increased prevalence of dry eye (DE) compared to age-matched population without glaucoma. Clinical presentation of DE varies among individuals and may significantly reduce quality of life. The onset and deterioration of DE is caused by the toxic-inflammatory effects of preservatives in eye drops, active substance itself, and added, pharmacologically inactive substances or excipients. Ocular surface changes most frequently include superficial punctate keratitis, tear film instability, and allergic reactions. Despite the lack of symptoms, clinical signs may indicate ocular surface damage. Discordance between signs and symptoms is partly caused by decreased corneal sensitivity induced by neurotoxicity of the preservative benzalkonium chloride (BAK). Therefore, it is important to evaluate ocular surface before initiating glaucoma therapy and during follow-up also in asymptomatic patients. Preservative-free and/or BAK-free therapy is indicated in patients with severe DE and allergy to preservatives, and recommended in patients with DE of moderate severity, blepharitis, in symptomatic patients, before filtering surgery to reduce preoperative inflammation, in those with moderate fluorescein staining of grade 2 on Oxford scheme, and reduced tear film break-up time.

Analysis of ocular surface damage and visual impact in patients with primary and secondary Sjögren syndrome

2020 ◽  
Vol 40 (8) ◽  
pp. 1249-1257 ◽  
Author(s):  
Antonio J. Villarreal-Gonzalez ◽  
I. Jocelyn Rivera-Alvarado ◽  
Luis A. Rodriguez-Gutierrez ◽  
Alejandro Rodriguez-Garcia
Keyword(s):  
Ocular Surface ◽  
Surface Damage ◽  
Sjögren Syndrome ◽  
Sjogren Syndrome ◽  
Visual Impact

scholarly journals The Protective Effect of a Topical Mucin Secretagogue on Ocular Surface Damage Induced by Airborne Carbon Black Exposure

2019 ◽  
Vol 60 (1) ◽  
pp. 255 ◽  
Author(s):  
Xiangzhe Li ◽  
Boram Kang ◽  
Youngsub Eom ◽  
Hyung Keun Lee ◽  
Hyo Myung Kim ◽  
...  
Keyword(s):  
Carbon Black ◽  
Protective Effect ◽  
Ocular Surface ◽  
Surface Damage
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