Polymorphonuclear Elastase in the Early Diagnosis of Complicated Pyogenic Pleural Effusions

Respiration ◽  
2003 ◽  
Vol 70 (5) ◽  
pp. 462-467 ◽  
Author(s):  
Carmen Alemán ◽  
José Alegre ◽  
Rosa M. Segura ◽  
Lluís Armadans ◽  
Josep M. Suriñach ◽  
...  
Keyword(s):  
Early Diagnosis ◽  
Pleural Effusions ◽  
Polymorphonuclear Elastase

Thoracoscopy in the Early Diagnosis of Malignant Pleural Effusions

Endoscopy ◽  
1980 ◽  
Vol 12 (04) ◽  
pp. 155-160 ◽  
Author(s):  
C. Boutin ◽  
P. Cargnino ◽  
J.R. Viallat
Keyword(s):  
Early Diagnosis ◽  
Pleural Effusions ◽  
Malignant Pleural Effusions

Association between inflammatory mediators and the fibrinolysis system in infectious pleural effusions

2003 ◽  
Vol 105 (5) ◽  
pp. 601-607 ◽  
Author(s):  
Carmen ALEMÁN ◽  
José ALEGRE ◽  
Jasone MONASTERIO ◽  
Rosa M. SEGURA ◽  
Lluís ARMADANS ◽  
...  
Keyword(s):  
Pleural Fluid ◽  
Inflammatory Mediators ◽  
Pearson Correlation ◽  
Fibrinolytic System ◽  
Tissue Type ◽  
Rank Test ◽  
Pleural Effusions ◽  
Polymorphonuclear Elastase ◽  
Tnf Α ◽  
Pai 1

The response of the fibrinolytic system to inflammatory mediators in empyema and complicated parapneumonic pleural effusions is still uncertain. We prospectively analysed 100 patients with pleural effusion: 25 with empyema or complicated parapneumonic effusion, 22 with tuberculous effusion, 28 with malignant effusion and 25 with transudate effusion. Inflammatory mediators, tumour necrosis factor-α (TNF-α), interleukin-8 (IL-8) and polymorphonuclear elastase, were measured in serum and pleural fluid. Fibrinolytic system parameters, plasminogen, tissue-type plasminogen activator (t-PA) and urokinase PA, PA inhibitor type 1 (PAI 1) and PAI type 2 concentrations and PAI 1 activity, were quantified in plasma and pleural fluid. The Wilcoxon signed-rank test was used to compare plasma and pleural values and to compare pleural values according to the aetiology of the effusion. The Pearson correlation coefficient was used to assess the relationship between fibrinolytic and inflammatory markers in pleural fluid. Significant differences were found between pleural and plasma fibrinolytic system levels. Pleural fluid exudates had higher fibrinolytic levels than transudates. Among exudates, tuberculous, empyema and complicated parapneumonic effusions demonstrated higher pleural PAI levels than malignant effusions, whereas t-PA was lowest in empyema and complicated parapneumonic pleural effusions. PAI concentrations correlated with TNF-α, IL-8 and polymorphonuclear elastase when all exudative effusions were analysed, but the association was not maintained in empyema and complicated parapneumonic effusions. A negative association found between t-PA and both IL-8 and polymorphonuclear elastase in exudative effusions was strongest in empyema and complicated parapneumonic effusions. Blockage of fibrin clearance in empyema and complicated parapneumonic effusions was associated with both enhanced levels of PAIs and decreased levels of t-PA.

scholarly journals EARLY DIAGNOSIS OF TUBERCULOUS PLEURAL EFFUSIONS AND ITS EFFECT ON PREVENTION OF OMINOUS RESULTS

CHEST Journal ◽  
2006 ◽  
Vol 130 (4) ◽  
pp. 242S
Author(s):  
Abolfazl Shirinzadeh dastgiri ◽  
Mohammadreza Miri ◽  
Amrullah Bayat ◽  
Ashraf Fakhajou ◽  
Vahid Montazeri ◽  
...  
Keyword(s):  
Early Diagnosis ◽  
Pleural Effusions

Diagnostic Accuracy of Pleural Fluid Polymorphonuclear Elastase in the Differentiation between Pyogenic Bacterial Infectious and Non-Infectious Pleural Effusions

Respiration ◽  
2000 ◽  
Vol 67 (4) ◽  
pp. 426-432 ◽  
Author(s):  
José Alegre ◽  
José Maria Suriñach ◽  
Encarna Varela ◽  
Lluis Armadans ◽  
Ramón Marti ◽  
...  
Keyword(s):  
Diagnostic Accuracy ◽  
Pleural Fluid ◽  
Pleural Effusions ◽  
Polymorphonuclear Elastase

Red Flags: Barriers to Listening and Spoken Language in Children with Hearing Loss

2014 ◽  
Vol 24 (1) ◽  
pp. 11-18
Author(s):  
Andrea Bell ◽  
K. Todd Houston
Keyword(s):  
Hearing Loss ◽  
Early Diagnosis ◽  
Skill Acquisition ◽  
Dynamic Process ◽  
Spoken Language ◽  
Red Flags ◽  
Careful Monitoring ◽  
Auditory Development ◽  
Children With Hearing Loss ◽  
Family Centered

To ensure optimal auditory development for the acquisition of spoken language, children with hearing loss require early diagnosis, effective ongoing audiological management, well fit and maintained hearing technology, and appropriate family-centered early intervention. When these elements are in place, children with hearing loss can achieve developmental and communicative outcomes that are comparable to their hearing peers. However, for these outcomes to occur, clinicians—early interventionists, speech-language pathologists, and pediatric audiologists—must participate in a dynamic process that requires careful monitoring of countless variables that could impact the child's skill acquisition. This paper addresses some of these variables or “red flags,” which often are indicators of both minor and major issues that clinicians may encounter when delivering services to young children with hearing loss and their families.

Neonatal Serum Electrolyte and Proteinuria Screening on 46,XY Ambiguous Genitalia Patients May Allow Early Diagnosis of Denys-Drash Syndrome: A Case Report

Urology ◽  
2020 ◽  
Author(s):  
Angelena Edwards ◽  
Niccolo M. Passoni ◽  
Rebecca Collins ◽  
Smitha Vidi ◽  
Jyothsna Gattineni ◽  
...  
Keyword(s):  
Case Report ◽  
Early Diagnosis ◽  
Ambiguous Genitalia ◽  
Serum Electrolyte ◽  
Drash Syndrome
Sign in / Sign up

Export Citation Format

Share Document