Variants of the Myocilin Gene in Japanese Patients with Normal-Tension Glaucoma

2003 ◽  
Vol 35 (6) ◽  
pp. 345-350 ◽  
Author(s):  
Kanako Izumi ◽  
Yukihiko Mashima ◽  
Minoru Obazawa ◽  
Yuichiro Ohtake ◽  
Tomihiko Tanino ◽  
...  
Keyword(s):  
Japanese Patients ◽  
Normal Tension Glaucoma

Mutations in the optineurin gene in Japanese patients with primary open-angle glaucoma and normal tension glaucoma

2004 ◽  
Vol 125A (1) ◽  
pp. 1-4 ◽  
Author(s):  
Yoshiki Toda ◽  
Sa Tang ◽  
Kenji Kashiwagi ◽  
Fumihiko Mabuchi ◽  
Hiroyuki Iijima ◽  
...  
Keyword(s):  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Japanese Patients ◽  
Normal Tension Glaucoma ◽  
Open Angle

scholarly journals Ocular hypotensive effects of prostaglandin analogs in Japanese patients with normal-tension glaucoma: a literature review

2018 ◽  
Vol Volume 12 ◽  
pp. 1837-1844 ◽  
Author(s):  
Yasutaka Takagi ◽  
Kazunori Santo ◽  
Masayo Hashimoto ◽  
Takeo Fukuchi
Keyword(s):  
Literature Review ◽  
Japanese Patients ◽  
Normal Tension Glaucoma

scholarly journals Stratification-Based Investigation of Adjunctive Brimonidine or Timolol to a Prostaglandin Analogue in Japanese Patients with Normal-Tension Glaucoma

2021 ◽  
Vol Volume 15 ◽  
pp. 2875-2883
Author(s):  
Keiji Yoshikawa ◽  
Shiro Mizoue ◽  
Koji Nitta ◽  
Hiroshi Onishi ◽  
Masaharu Ikeda ◽  
...  
Keyword(s):  
Japanese Patients ◽  
Normal Tension Glaucoma ◽  
Prostaglandin Analogue

scholarly journals Effect on Intraocular Pressure of Switching from Latanoprost and Travoprost Monotherapy to Timolol Fixed Combinations in Patients with Normal-Tension Glaucoma

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Ryoko Igarashi ◽  
Tetsuya Togano ◽  
Yuta Sakaue ◽  
Takaiko Yoshino ◽  
Jun Ueda ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Combination Therapy ◽  
Beta Blocker ◽  
Fixed Combination ◽  
Japanese Patients ◽  
Normal Tension Glaucoma ◽  
Pressure Reduction ◽  
Conjunctival Injection ◽  
Intraocular Pressure Reduction ◽  
The Mean

Purpose. To evaluate the effect on intraocular pressure (IOP) of switching from latanoprost and travoprost monotherapy to timolol fixed combinations in Japanese patients with normal-tension glaucoma (NTG).Methods. 27 NTG patients (54 eyes) were compared IOP, superficial punctuate keratitis (SPK) scores, and conjunctival injection scores in eyes treated with prostaglandin (PG) or PG analog/beta-blocker (PG/b) fixed-combination 6 months after the change in therapy.Results. The mean baseline intraocular pressure was17.4±1.59 mmHg in eyes receiving PG therapy only and17.4±1.69 mmHg in eyes switched to PG/b. Switching to fixed combination therapy from PG monotherapy, the mean IOP was13.1±1.79 mmHg(P<0.001)  (-24.71% reduction from baseline) at 6 months. The mean conjunctival injection score was 0.69 for eyes on PG monotherapy and 0.56 for eyes on fixed combination therapy(P=0.028). The mean SPK scores were 0.46 and 0.53. This difference was not statistically significant(P=0.463).Conclusions. Switching from PG monotherapy to PG/b fixed combination therapy for NTG resulted in a greater intraocular pressure reduction than PG alone without increasing the number of instillations.

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