Growth Hormone Suppression: Diagnosis of Growth Hormone Excess and Hyperprolactinemia

2003 ◽  
pp. 200-211 ◽  
Author(s):  
H. Frisch ◽  
S. Riedl
Keyword(s):  
Growth Hormone ◽  
Growth Hormone Suppression

Restoration of gallbladder contractility after withdrawal of long-term octreotide therapy in acromegalic patients

1993 ◽  
Vol 129 (3) ◽  
pp. 207-212 ◽  
Author(s):  
Yi-Fan Shi ◽  
Xian-Feng Zhu ◽  
Alan G Harris ◽  
Jin-Xi Zhang ◽  
Jie-Ying Deng
Keyword(s):  
Growth Hormone ◽  
Growth Factor ◽  
Term Therapy ◽  
Serum Growth Hormone ◽  
Factor I ◽  
Gallbladder Contractility ◽  
Octreotide Therapy ◽  
Long Term Therapy ◽  
Growth Hormone Suppression

We sought to examine how the discontinuation of octreotide in long-term octreotide-treated acromegalic patients affects the well-documented side-effect of cholelithiasis. In 14 acromegalic patients, serum growth hormone levels, insulin-like growth factor I levels and percentage of relative gallbladder contractility were measured prior to and after the discontinuation of octreotide. Compared to pretreatment values, the basal growth hormone and 5-h growth hormone profiles were 36% and 24%, and 60% and 56% at the end of 1 and 2 weeks, respectively. Octreotide was found to be eliminated completely from the serum within 3 days after its withdrawal. In all of six patients who did not develop gallstones, the percentage relative gallbladder contractility normalized within 1 week. In eight patients who developed gallstones, four of them had restoration of normal contractility within 2 weeks. Our results show that upon withdrawal of octreotide, gallbladder contractility returns to normal while growth hormone suppression persists for a longer period of time. Therefore, discontinuation of octreotide therapy may allow for the clearance of stagnated bile and hence decrease the incidence of cholelithiasis in acromegalic patients receiving long-term therapy.

Cellular mechanism of caprylic acid-induced growth hormone suppression

Metabolism ◽  
1990 ◽  
Vol 39 (10) ◽  
pp. 1108-1112 ◽  
Author(s):  
G. Renier ◽  
T. Abribat ◽  
P. Brazeau ◽  
N. Deslauriers ◽  
P. Gaudreau
Keyword(s):  
Growth Hormone ◽  
Caprylic Acid ◽  
Cellular Mechanism ◽  
Growth Hormone Suppression

scholarly journals Effect of Growth Hormone Suppression on Exercise Training and Growth Responses in Young Rats

1994 ◽  
Vol 35 (2) ◽  
pp. 223-227 ◽  
Author(s):  
Dan M Cooper ◽  
David Moromisato ◽  
Stefania Zanconato ◽  
Mark Moromisato ◽  
Steven Jensen ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Exercise Training ◽  
Growth Responses ◽  
Young Rats ◽  
Growth Hormone Suppression

scholarly journals Integrated Transcriptional and Proteomic Analysis of Growth Hormone Suppression Mediated by Trichothecene T-2 Toxin in Rat GH3 Cells

2015 ◽  
Vol 147 (2) ◽  
pp. 326-338 ◽  
Author(s):  
Dan Wan ◽  
Xu Wang ◽  
Qinghua Wu ◽  
Pingping Lin ◽  
Yuanhu Pan ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Proteomic Analysis ◽  
Gh3 Cells ◽  
Growth Hormone Suppression

Impact of Growth Hormone Suppression in the Aging Process and Preliminary Longevity Analysis

2006 ◽  
Vol 928 (1) ◽  
pp. 362-362 ◽  
Author(s):  
Isao Shimokawa ◽  
Yoshikazu Higami ◽  
Kurumi Yanagihara-Outa ◽  
Kenji Tanaka ◽  
Tomoshi Tuchiya ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Aging Process ◽  
Growth Hormone Suppression
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