Preservation of Endothelial Function by the HMG-CoA Reductase Inhibitor Fluvastatin through Its Lipid-Lowering Independent Antioxidant Properties in Atherosclerotic Rabbits

Pharmacology ◽  
2003 ◽  
Vol 68 (3) ◽  
pp. 121-130 ◽  
Author(s):  
Hironobu Mitani ◽  
Kensuke Egashira ◽  
Noriko Ohashi ◽  
Masayoshi Yoshikawa ◽  
Satoru Niwa ◽  
...  
Keyword(s):  
Endothelial Function ◽  
Reductase Inhibitor ◽  
Antioxidant Properties ◽  
Lipid Lowering ◽  
Hmg Coa Reductase ◽  
Hmg Coa Reductase Inhibitor ◽  
Coa Reductase

Discovery of a new class of HMG-CoA reductase inhibitor from Polyalthia longifolia as potential lipid lowering agent

2011 ◽  
Vol 46 (10) ◽  
pp. 5206-5211 ◽  
Author(s):  
Koneni V. Sashidhara ◽  
Suriya P. Singh ◽  
Anuj Srivastava ◽  
Anju Puri ◽  
Yashpal S. Chhonker ◽  
...  
Keyword(s):  
Reductase Inhibitor ◽  
Lipid Lowering ◽  
Hmg Coa Reductase ◽  
New Class ◽  
Hmg Coa Reductase Inhibitor ◽  
Lipid Lowering Agent ◽  
Coa Reductase ◽  
Polyalthia Longifolia

The lipid-lowering effects of atorvastatin, a new HMG-CoA reductase inhibitor: results of a randomized, double-masked study

1996 ◽  
Vol 18 (5) ◽  
pp. 853-863 ◽  
Author(s):  
Therese M. Heinonen ◽  
Evan Stein ◽  
Stuart R. Weiss ◽  
James M. McKenney ◽  
Michael Davidson ◽  
...  
Keyword(s):  
Reductase Inhibitor ◽  
Lipid Lowering ◽  
Hmg Coa Reductase ◽  
Hmg Coa Reductase Inhibitor ◽  
Coa Reductase

scholarly journals Pitavastatin, an HMG-CoA Reductase Inhibitor, Ameliorates Endothelial Function in Chronic Smokers

2010 ◽  
Vol 74 (1) ◽  
pp. 195-202 ◽  
Author(s):  
Osamu Yoshida ◽  
Takahisa Kondo ◽  
Yasuko Kureishi-Bando ◽  
Tomonori Sugiura ◽  
Kengo Maeda ◽  
...  
Keyword(s):  
Endothelial Function ◽  
Reductase Inhibitor ◽  
Hmg Coa Reductase ◽  
Hmg Coa Reductase Inhibitor ◽  
Coa Reductase

scholarly journals Pitavastatin, an HMG-CoA Reductase Inhibitor, Ameliorates Endothelial Function in Chronic Smokers

2010 ◽  
Vol 74 (2) ◽  
pp. 386
Author(s):  
Osamu Yoshida ◽  
Takahisa Kondo ◽  
Yasuko Kureishi-Bando ◽  
Tomonori Sugiura ◽  
Kengo Maeda ◽  
...  
Keyword(s):  
Endothelial Function ◽  
Reductase Inhibitor ◽  
Hmg Coa Reductase ◽  
Hmg Coa Reductase Inhibitor ◽  
Coa Reductase

scholarly journals Role of HMG-COA reductase inhibitor and allium sativum on lipid profile in diabetic dyslipidemic patients: A comparative study.

2020 ◽  
Vol 27 (02) ◽  
pp. 353-358
Author(s):  
Naveed Ali Siddiqui ◽  
Fatima Bint Taj ◽  
Imran Ishaque ◽  
Ayesha Shahid ◽  
Ayesha Ayaz
Keyword(s):  
Lipid Profile ◽  
Reductase Inhibitor ◽  
Allium Sativum ◽  
Density Lipoprotein ◽  
Herbal Product ◽  
Lipoprotein Cholesterol ◽  
Lipid Lowering ◽  
Hmg Coa Reductase ◽  
Hmg Coa Reductase Inhibitor ◽  
Coa Reductase

Objectives: To evaluate the changes in lipid profile in patients with diabetic dyslipidemia using lipid lowering drug, simvastatin and herbal product allium sativum. Study Design: Clinical trial. Setting: Surgeon Munawar Memorial Hospital, Karachi. Period: 1st January 2017 to 30th April 2017. Material & Methods: The study was designed to assess the effects of hmg-coa reductase inhibitor (simvastatin) and allium sativum on lipid profile in patients with diabetic dysplipidemia. The exclusion criteria included lactating/pregnant women’s, renal, liver and established coronary artery disease. Results: Sixty patients with abnormal lipid profile were included in the study (age 30-60 years). Patients were divided into two groups (30 patients each). Group a was orally administered with product of simvastatin (20 mg)/day for 04 months and in group b, patients were orally administered with herbal product of allium sativum (300 mg)/day for 04 months. Conclusion: On the basis of this study it is observed that allium sativum as well as simvastatin tablets both reduce total cholesterol, low density lipoprotein cholesterol (ldl-c) and increase high density lipoprotein cholesterol (hdl-c).

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