Session IIIb: Non-Human NK Receptors

1998 ◽  
Vol 16 (2-3) ◽  
pp. 88-101
Keyword(s):  
Nk Receptors

Suppressive Effect of a Standardized Mistletoe Extract on the Expression of Activatory NK Receptors and Function of Human NK Cells

2007 ◽  
Vol 27 (5) ◽  
pp. 477-485 ◽  
Author(s):  
Soo Jung Lee ◽  
Young-Ok Son ◽  
Hyunjin Kim ◽  
Joo-Young Kim ◽  
Soon-Won Park ◽  
...  
Keyword(s):  
Nk Cells ◽  
Suppressive Effect ◽  
Nk Receptors ◽  
Mistletoe Extract ◽  
And Function

IL-15 induces CD8+ T cells to acquire functional NK receptors capable of modulating cytotoxicity and cytokine secretion

Immunobiology ◽  
2011 ◽  
Vol 216 (5) ◽  
pp. 604-612 ◽  
Author(s):  
Margareta P. Correia ◽  
Alexandra V. Costa ◽  
Markus Uhrberg ◽  
Elsa M. Cardoso ◽  
Fernando A. Arosa
Keyword(s):  
T Cells ◽  
Cd8 T Cells ◽  
Cytokine Secretion ◽  
Nk Receptors

scholarly journals Human antimicrobial cytotoxic T lymphocytes, defined by NK receptors and antimicrobial proteins, kill intracellular bacteria

2018 ◽  
Vol 3 (26) ◽  
pp. eaat7668 ◽  
Author(s):  
Samuel J. Balin ◽  
Matteo Pellegrini ◽  
Eynav Klechevsky ◽  
Sohui T. Won ◽  
David I. Weiss ◽  
...  
Keyword(s):  
T Lymphocytes ◽  
Cytotoxic T Lymphocytes ◽  
Intracellular Bacteria ◽  
Antimicrobial Proteins ◽  
Nk Receptors

scholarly journals Evolution of NK receptors: a single Ly49 and multiple KIR genes in the cow

2002 ◽  
Vol 32 (3) ◽  
pp. 810 ◽  
Author(s):  
Karina L. McQueen ◽  
Brian T. Wilhelm ◽  
Kristin D. Harden ◽  
Dixie L. Mager
Keyword(s):  
Nk Receptors ◽  
Kir Genes

scholarly journals NKG2D recognition mediates Toll-like receptor 3 signaling-induced breakdown of epithelial homeostasis in the small intestines of mice

2007 ◽  
Vol 104 (18) ◽  
pp. 7512-7515 ◽  
Author(s):  
Rongbin Zhou ◽  
Haiming Wei ◽  
Rui Sun ◽  
Jian Zhang ◽  
Zhigang Tian
Keyword(s):  
Tissue Injury ◽  
Mucosal Injury ◽  
Intraepithelial Lymphocytes ◽  
Cell Contact ◽  
Dependent Manner ◽  
Tlr Signaling ◽  
Nk Receptors ◽  
Polycytidylic Acid ◽  
Self Tolerance ◽  
Polyinosinic Polycytidylic Acid

Toll-like receptors (TLRs) and NK receptors are the two most important receptor families in innate immunity. Although it has been observed that TLR signaling can induce or up-regulate the expression of the ligands for stimulatory NK receptors on monocytes or muscle cells, there is not yet a report indicating whether TLR signaling can break down self-tolerance through NK receptors. The present work reports that TLR3 signaling by polyinosinic–polycytidylic acid stimulation induces intestinal epithelial cells (IECs) to express retinoic acid early inducible-1 (a ligand for NKG2D) and to induce NKG2D expression on CD8αα intestinal intraepithelial lymphocytes by IL-15 derived from TLR3-activated IECs. The blockade of interaction between NKG2D and Rae1 inhibits the cytotoxicity of intraepithelial lymphocytes against IECs in a cell–cell contact-dependent manner and therefore alleviates polyinosinic–polycytidylic acid-induced epithelial destruction and acute mucosal injury of small intestine. These results demonstrate that TLR signaling induces tissue injury through the NKG2D pathway, suggesting that TLR signaling may break down self-tolerance through induction of abnormal expression of ligands for stimulatory NK receptors.

scholarly journals Enhanced Recognition of Human NK Receptors After Influenza Virus Infection

2003 ◽  
Vol 171 (2) ◽  
pp. 915-923 ◽  
Author(s):  
Hagit Achdout ◽  
Tal I. Arnon ◽  
Gal Markel ◽  
Tsufit Gonen-Gross ◽  
Gil Katz ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Virus Infection ◽  
Influenza Virus Infection ◽  
Nk Receptors
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