Prognostic Significance of the Number of Metastatic Lymph Nodes in Early Gastric Cancer

2003 ◽  
Vol 20 (2) ◽  
pp. 148-153 ◽  
Author(s):  
Yoshio Gunji ◽  
Takao Suzuki ◽  
Seiji Hori ◽  
Hideki Hayashi ◽  
Hisahiro Matsubara ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Early Gastric Cancer ◽  
Lymph Nodes ◽  
Prognostic Significance ◽  
Metastatic Lymph Nodes ◽  
Metastatic Lymph

Comparison of the prognostic significance between the number of metastatic lymph nodes and nodal stage based on their location in patients with gastric cancer.

1993 ◽  
Vol 11 (10) ◽  
pp. 1894-1900 ◽  
Author(s):  
T Ichikura ◽  
S Tomimatsu ◽  
Y Okusa ◽  
K Uefuji ◽  
S Tamakuma
Keyword(s):  
Gastric Cancer ◽  
Multivariate Analysis ◽  
Survival Rate ◽  
Lymph Nodes ◽  
Prognostic Significance ◽  
Cox Proportional Hazards Model ◽  
Depth Of Invasion ◽  
Metastatic Lymph Nodes ◽  
Nodal Stage ◽  
Metastatic Lymph

PURPOSE To determine which is the better prognostic determinant in gastric cancer: number of positive metastatic lymph nodes or current nodal stage. PATIENTS AND METHODS Seven hundred seventy-seven patients who underwent potentially curative resections for gastric cancer were divided into three groups according to the depth of invasion. The influence of the number of positive nodes on their survival rate was analyzed. A multivariate analysis by the Cox proportional hazards model was used to determine independent prognostic factors. RESULTS A decreased survival rate was associated with an increased number of positive nodes in all of the subjects and in each of the three groups. Patients with one to three positive nodes had as good a prognosis as those without nodal involvement when each of the three groups was analyzed separately. Using a multivariate analysis in the patients with four or more positive nodes, we found that the number of positive nodes was the most important prognostic determinant (P < .0001), followed by the depth of invasion (P < .02), and that the nodal stage was not significantly prognostic. Further multivariate analysis in the patients with one to three positive nodes showed that nodal stage and number of positive nodes were not significantly prognostic. CONCLUSION The number of metastatic nodes should be adopted for classification of nodal stage in gastric cancer.

Validation study of sentinel lymph node mapping using radio- and dye-guided methods in gastric cancer: 431 cases at a single institution.

2011 ◽  
Vol 29 (4_suppl) ◽  
pp. 76-76
Author(s):  
M. Niihara ◽  
H. Takeuchi ◽  
S. Kamiya ◽  
T. Kaburagi ◽  
T. Oyama ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Early Gastric Cancer ◽  
Lymph Nodes ◽  
False Negative ◽  
Tumor Diameter ◽  
Remnant Gastric Cancer ◽  
Metastatic Lymph Nodes ◽  
Metastatic Lymph

76 Background: Some papers have reported that sentinel lymph node (SLN) concept can be applied in patients with early gastric cancer, in particular clinically T1N0M0 or T2N0M0 with a tumor diameter of 4cm or less. Little is, however, available on the SLN study with the other criteria than listed above. The aim of the present work was to investigate the accuracy of the SLN biopsy of gastric cancer with various stages and evaluate the indication for SLN navigated gastrectomy. Methods: A total of 431 consecutive patients were diagnosed with operable gastric cancer during the period April 1999 through December 2007. Reasons for inclusion were, in principle, T1N0M0 or T2N0M0 gastric cancer. However, several patients diagnosed preoperatively with T3N0M0, T2N1M0, remnant gastric cancer, multiple gastric cancers and additional treatment after endoscopic therapy were also enrolled in this study according to their request. All patients underwent a radical gastrectomy with SLN mapping with an informed consent. The SLNs were identified using both radio-guided and dye-guided method. Results: Detection rate of hot and/or blue node was 95.8% (413/431). The accuracy of metastatic status based on SLN was 97.6% (403/413). In six of 10 false-negative cases, some clinical backgrounds and problems were present; scirrhous gastric cancer, the tumor penetration of serosa, multiple lesions, remnant gastric cancer after partial resection and the technical issue of tracer injection. Nine of these 10 false-negative cases had the metastatic lymph nodes within only the sentinel basins. Specifically, in the group of clinically T1N0M0 untreated gastric cancer with a tumor diameter of 4 cm or less, there were only 3 false- negative cases. In addition, all the metastatic lymph nodes of the 3 cases located within the sentinel basins. Conclusions: Our study suggested that SLN concept for untreated early gastric cancer could be validated. The sentinel basin dissection might be used to advantage to improve curativity for gastric cancer. No significant financial relationships to disclose.

The distribution pattern of metastatic lymph nodes after non‐curative endoscopic resection in early gastric cancer

2018 ◽  
Vol 118 (8) ◽  
pp. 1257-1263 ◽  
Author(s):  
Quetzalihuitl Arroyo‐Martinez ◽  
Won Ho Han ◽  
Bang Wool Eom ◽  
Hong Man Yoon ◽  
Young Il Kim ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Early Gastric Cancer ◽  
Lymph Nodes ◽  
Distribution Pattern ◽  
Endoscopic Resection ◽  
Metastatic Lymph Nodes ◽  
Metastatic Lymph

Prognostic significance of the number of metastatic lymph nodes in patients with gastric cancer

1991 ◽  
Vol 47 (1) ◽  
pp. 12-16 ◽  
Author(s):  
Masato Makino ◽  
Seiji Moriwaki ◽  
Masao Yonekawa ◽  
Michio Oota ◽  
Osamu Kimura ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Lymph Nodes ◽  
Prognostic Significance ◽  
Metastatic Lymph Nodes ◽  
Metastatic Lymph

scholarly journals Prognostic value of fibrosis ratio in metastatic lymph nodes of node-positive advanced gastric cancer

Medicine ◽  
2018 ◽  
Vol 97 (3) ◽  
pp. e9703 ◽  
Author(s):  
Soon Auck Hong ◽  
Myoung Won Son ◽  
Junhun Cho ◽  
Chung Hun Lee ◽  
Si-Hyeong Jang ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Lymph Nodes ◽  
Advanced Gastric Cancer ◽  
Prognostic Value ◽  
Metastatic Lymph Nodes ◽  
Node Positive ◽  
Metastatic Lymph
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