Unoprostone Isopropyl Pretreatment Decreases Endothelin-1 Release and the Intra-Ocular Pressure Spike Induced by Laser Trabeculoplasty in the Rabbit

2003 ◽  
Vol 217 (3) ◽  
pp. 231-236 ◽  
Author(s):  
Gábor Holló ◽  
Zsuzsanna Visontai ◽  
Péter Lakatos ◽  
Péter Vargha
Keyword(s):  
Endothelin 1 ◽  
Intra Ocular Pressure ◽  
Laser Trabeculoplasty ◽  
Pressure Spike ◽  
Ocular Pressure

Intra-ocular pressure spike after Aflibercept and Ranibizumab intravitreal injections

2015 ◽  
Vol 93 ◽  
pp. n/a-n/a
Author(s):  
H. El Chehab ◽  
E. Agard ◽  
A. Russo ◽  
A. Malcles ◽  
C. Dot
Keyword(s):  
Intravitreal Injections ◽  
Intra Ocular Pressure ◽  
Pressure Spike ◽  
Ocular Pressure

scholarly journals Review on Commonly used Medical Therapies for Glaucoma

2020 ◽  
Vol 11 (4) ◽  
pp. 8054-8060
Author(s):  
Bhatt Tarang R ◽  
Golwala Dharmesh K
Keyword(s):  
Beta Blockers ◽  
Alternative Therapy ◽  
Argon Laser ◽  
Major Drawback ◽  
Intra Ocular Pressure ◽  
Laser Trabeculoplasty ◽  
Sustained Reduction ◽  
Ocular Pressure ◽  
Total Blindness ◽  
Topical Medications

Glaucoma is a multipart disorder which leads to continuous degeneration of the optic nerve leading to partial or total blindness. Topical medications are the most common form of therapy to patients. All medication used in glaucoma acts either decreasing the production of aqueous humour and/or by enhancing its outflow, which aids in reducing intra ocular pressure. Medications that cause a decline in aqueous humor secretion are beta-blockers, a2 agonists, and carbonic anhydrase inhibitors. While medications that enhances aqueous drainage include Cholinergic agonists, prostaglandin analogues and adrenergic agonists. Amongst all the drugs, latanoprost and its combinations offer the highest reduction in intra-ocular pressure, but its instability at room temperature is a major drawback to patients. All types of alternative therapy are still at an initial stage, and there are various scopes of development, and further clinical studies will provide more insight. And surgical procedures, which are mainly Argon laser trabeculoplasty and Selective laser trabeculoplasty, are currently preferred, which provides effective results for the patients, but it is not very suitable for all the patients, and there are a few post-operative complications. Thus, modern research on the reduction of dose, precise drug delivery and sustained reduction of IOP shall help in improvising the medications of glaucoma and help mankind from this serious vision-threatening disease.

scholarly journals Effect of trabeculectomy and canaloplasty on intra-ocular pressure modifications after postural changes in open-angle glaucoma

2014 ◽  
Vol 92 (6) ◽  
pp. e498-e499 ◽  
Author(s):  
Luciano Quaranta ◽  
Elena Biagioli ◽  
Ivano Riva ◽  
Claudia Tosoni ◽  
Paolo Brusini ◽  
...  
Keyword(s):  
Open Angle Glaucoma ◽  
Open Angle ◽  
Intra Ocular Pressure ◽  
Postural Changes ◽  
Ocular Pressure

Intra-ocular pressure changes during maximal isometric contraction: Does this reflect intra-cranial pressure or retinal venous pressure?

1999 ◽  
Vol 21 (3) ◽  
pp. 243-246 ◽  
Author(s):  
Rob D. Dickerman ◽  
Greg H. Smith ◽  
Len Langham-Roof ◽  
Walter J. McConathy ◽  
John W. East ◽  
...  
Keyword(s):  
Isometric Contraction ◽  
Venous Pressure ◽  
Retinal Venous Pressure ◽  
Intra Ocular Pressure ◽  
Ocular Pressure ◽  
Pressure Changes ◽  
Intra Cranial Pressure

Telemedicine in the control of intra-ocular pressure

2000 ◽  
Vol 6 (1_suppl) ◽  
pp. 126-128 ◽  
Author(s):  
G Michelson ◽  
W Striebel ◽  
W Prihoda ◽  
Volker Schmidt
Keyword(s):  
Cost Effective ◽  
Western World ◽  
Pressure Curve ◽  
Effective Technique ◽  
Intra Ocular Pressure ◽  
Continuous Evaluation ◽  
Common Causes ◽  
Cost Effective Technique ◽  
Email Message ◽  
Ocular Pressure

Glaucoma is one of the most common causes of blindness in the Western world and a major risk factor is increased intra-ocular pressure. We therefore used telemedicine in its control. Patients measured their intra-ocular pressure several times a day with a portable instrument and the values were then entered into a portable digital assistant. These data were transmitted by a modem to a central server. If the intra-ocular pressure was pathologically high, an email message was automatically sent to the ophthalmologist. The pressure curve, including a statistical analysis, was displayed in an easily readable chart format. Ten patients with glaucoma participated in a trial. Self-tonometry with telemedicine enabled continuous evaluation of the patient by the ophthalmologist. This approach offered the advantage of controlling the treatment remotely. Advantages for the patient were that the measurements were easily done at home under normal conditions, and the patient could control when the measurement and data transmission would be performed. Telemedicine is a cost-effective technique enabling the early diagnosis of pathologically increased intra-ocular pressure.

Oral drugs for glaucoma

1965 ◽  
Vol 3 (25) ◽  
pp. 99-100
Keyword(s):  
Carbonic Anhydrase ◽  
Anterior Chamber ◽  
Peripheral Vision ◽  
Oral Drugs ◽  
Carbonic Anhydrase Inhibitors ◽  
Intra Ocular Pressure ◽  
Ocular Pressure ◽  
Minor Operations ◽  
Closed Angle ◽  
Short Time

To prevent loss of peripheral vision in chronic glaucoma uninterrupted control of intra-ocular pressure is important, and we have discussed the use of local applications for this.1 A carbonic anhydrase inhibitor given by mouth may be a useful adjunct to treatment when intra-ocular pressure cannot be controlled by local applications alone or by operations such as cutting a drainage channel from the anterior chamber to the subconjunctival tissue. Carbonic anhydrase inhibitors may also usefully reduce tension for a short time in acute closed angle glaucoma (where the drainage angle of the anterior chamber is blocked), in acute glaucoma due to uveitis (the commonest cause of secondary glaucoma) and before operations for glaucoma. Their use is dangerous if they mask symptoms and so delay surgery; and thus for eye conditions carbonic anhydrase inhibitors are best given only on the advice of an ophthalmologist. The value of certain minor operations (e.g. trabeculotomy) which may increase the responsiveness of the eye to drugs is being investigated.

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