Postural Skin Colour Changes during the Corticosteroid Blanching Assay

1999 ◽  
Vol 12 (4) ◽  
pp. 199-210 ◽  
Author(s):  
F. Henry ◽  
I. Fumal ◽  
G.E. Piérard
Keyword(s):  
1982 ◽  
Vol 106 (4) ◽  
pp. 437-444 ◽  
Author(s):  
J. W. FEATHER ◽  
K.S. RYATT ◽  
J.B. DAWSON ◽  
J.A. COTTERILL ◽  
D.J. BARKER ◽  
...  

2020 ◽  
Author(s):  
Kinjiro Amano ◽  
Kaida Xiao ◽  
Sophie Wuerger ◽  
Georg Meyer

AbstractThe main ingredient of sunless tanning products is dihydroxyacetone (DHA). DHA reacts with the protein and amino acid composition in the surface layers of the skin, producing melanoidins, which changes the skin colour, imitating natural skin tan caused by melanin. The purpose of this study was to characterise DHA-induced skin colour changes and to test whether we can predict the outcome of DHA application on skin tone changes.To assess the DHA-induced skin colour shift quantitatively, colorimetric and spectral measurements of the inner forearm were obtained before, four hours and 24 hours after application of a 7.5% concentration DHA gel in the experimental group (n = 100). In a control group (n = 60), the same measurements were obtained on both the inner forearm (infrequently sun-exposed) and the outer forearm (frequently sun-exposed); the difference between these two areas was defined as the naturally occurring tan. Skin colour shifts caused by DHA tanning and by natural tanning were compared in terms of lightness (L*), redness (a*) and yellowness (b*) in the standard CIELAB colour space. Naturalness of the DHA-induced skin tan was evaluated by comparing the trajectory of the chromaticity distribution in (L*, b*) space with that of naturally occurring tan. Twenty-four hours after DHA application, approximately 20% of the skin colour samples became excessively yellow, with chromaticities outside the natural range in (L*, b*) space. A principal component analysis was used to characterise the tanning pathway. Skin colour shifts induced by DHA were predicted by a multiple regression on the chromaticities and the skin properties. The model explained up to 49% of variance in colorimetric components with a median error of less than 2 ΔE. We conclude that the control of both the magnitude and the direction of the colour shift is a critical factor to achieve a natural appearance.


1971 ◽  
Vol 68 (2) ◽  
pp. 264-270 ◽  
Author(s):  
N. H. Gopal Dutt ◽  
M. R. Rajasekharasetty

ABSTRACT The administration of pentobarbital sodium (nembutal) at low concentration causes darkening of the skin. However, at higher dose or after prolonged treatment a moderate blanching of the skin is noticed. Nialamide also produces a moderate blanching effect. Both these drugs considerably increase the number of colloid vesicles in the pars intermedia of the frog, Rana cyanophlyctis. These drugs, however, do not reverse the darkening of the skin due to ACTH in hypophysectomized frogs. Histochemical analysis suggests that the colloid vesicles may represent stored melanophore-stimulating hormone.


2009 ◽  
Vol 11 (2) ◽  
pp. 159-193 ◽  
Author(s):  
Eric Leclercq ◽  
John F Taylor ◽  
Hervé Migaud
Keyword(s):  

1995 ◽  
Vol 47 (1) ◽  
pp. 143-154 ◽  
Author(s):  
J. Davenport ◽  
C. Bradshaw
Keyword(s):  

Author(s):  
Keyvan Karimi Galougahi

Abstract This report describes persistent paresthesia, haemodynamic changes including orthostatic tachycardia, and skin colour changes due to autonomic dysfunction after a single dose of the ChAdOx1-nCoV-19 vaccine (AstraZeneca) in a healthy 29-year-old male.


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