Role of GABAB Receptor in the Regulation of Excitatory Synaptic Transmission in Trigeminal Motoneurons

2002 ◽  
Vol 9 (4) ◽  
pp. 348-358 ◽  
Author(s):  
Ming-Yuan Min ◽  
Kwabena Appenteng ◽  
Hsiu-Wen Yang
Keyword(s):  
Synaptic Transmission ◽  
Excitatory Synaptic Transmission ◽  
Trigeminal Motoneurons

scholarly journals Influences of Morphine on the Spontaneous and Evoked Excitatory Postsynaptic Currents in Lateral Amygdala of Rats

2016 ◽  
pp. 165-169 ◽  
Author(s):  
J.-J. ZHANG ◽  
X.-D. LIU ◽  
L.-C. YU
Keyword(s):  
Synaptic Transmission ◽  
Excitatory Synaptic Transmission ◽  
Morphine Treatment ◽  
Lateral Amygdala ◽  
Excitatory Postsynaptic Currents ◽  
Postsynaptic Currents ◽  
Whole Cell Patch Clamp ◽  
The Central Nervous System ◽  
Underlying Mechanisms

Acute morphine exposure induces antinociceptive activity, but the underlying mechanisms in the central nervous system are unclear. Using whole-cell patch clamp recordings, we explore the role of morphine in the modulation of excitatory synaptic transmission in lateral amygdala neurons of rats. The results demonstrate that perfusion of 10 μM of morphine to the lateral amygdala inhibits the discharge frequency significantly. We further find that there are no significant influences of morphine on the amplitude of spontaneous excitatory postsynaptic currents (sEPSCs). Interestingly, morphine shows no marked influence on the evoked excitatory postsynaptic currents (eEPSCs) in the lateral amygdala neurons. These results indicate that acute morphine treatment plays an important role in the modulation on the excitatory synaptic transmission in lateral amygdala neurons of rats.

scholarly journals The Cell-Autonomous Role of Excitatory Synaptic Transmission in the Regulation of Neuronal Structure and Function

Neuron ◽  
2013 ◽  
Vol 78 (3) ◽  
pp. 433-439 ◽  
Author(s):  
Wei Lu ◽  
Eric A. Bushong ◽  
Tiffany P. Shih ◽  
Mark H. Ellisman ◽  
Roger A. Nicoll
Keyword(s):  
Synaptic Transmission ◽  
Structure And Function ◽  
Excitatory Synaptic Transmission ◽  
Neuronal Structure ◽  
And Function
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