Motor Cortex Stimulation for Phantom Limb Pain: Comprehensive Therapy with Spinal Cord and Thalamic Stimulation

2001 ◽  
Vol 77 (1-4) ◽  
pp. 159-162 ◽  
Author(s):  
Yoichi Katayama ◽  
Takamitsu Yamamoto ◽  
Kazutaka Kobayashi ◽  
Masahiko Kasai ◽  
Hideki Oshima ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Motor Cortex ◽  
Phantom Limb Pain ◽  
Phantom Limb ◽  
Motor Cortex Stimulation ◽  
Limb Pain ◽  
Thalamic Stimulation ◽  
Comprehensive Therapy

Analysis of cortical reorganization (CR) of the patients with phantom-limb pain and the mechanism of motor cortex stimulation

2007 ◽  
Vol 58 ◽  
pp. S29
Author(s):  
Youichi Saitoh ◽  
Takufumi Yanagisawa ◽  
Satoru Oshino ◽  
Masayuki Hirata ◽  
Tetsu Goto ◽  
...  
Keyword(s):  
Motor Cortex ◽  
Phantom Limb Pain ◽  
Cortical Reorganization ◽  
Phantom Limb ◽  
Motor Cortex Stimulation ◽  
Limb Pain

Long-term motor cortex stimulation for phantom limb pain

2014 ◽  
Vol 29 (2) ◽  
pp. 272-274 ◽  
Author(s):  
Erlick A.C. Pereira ◽  
Tom Moore ◽  
Liz Moir ◽  
Tipu Z. Aziz
Keyword(s):  
Motor Cortex ◽  
Phantom Limb Pain ◽  
Phantom Limb ◽  
Motor Cortex Stimulation ◽  
Limb Pain

Chronic Motor Cortex Stimulation for Phantom Limb Pain Control: Correlations between Analgesic Effects and Cortex Mapping

Neurosurgery ◽  
2005 ◽  
Vol 57 (2) ◽  
pp. 413-413
Author(s):  
Yves Lazorthes ◽  
Jean-Christophe Sol ◽  
Pascal Cintas ◽  
Jean-Albert Lotterie ◽  
Jean-Claude Verdie ◽  
...  
Keyword(s):  
Motor Cortex ◽  
Pain Control ◽  
Phantom Limb Pain ◽  
Phantom Limb ◽  
Motor Cortex Stimulation ◽  
Limb Pain ◽  
Analgesic Effects

Motor cortex stimulation for phantom limb pain

The Lancet ◽  
1999 ◽  
Vol 353 (9148) ◽  
pp. 212 ◽  
Author(s):  
Youichi Saitoh ◽  
Masahiko Shibata ◽  
Yasuhiro Sanada ◽  
Takashi Mashimo
Keyword(s):  
Motor Cortex ◽  
Phantom Limb Pain ◽  
Phantom Limb ◽  
Motor Cortex Stimulation ◽  
Limb Pain

Chronic Motor Cortex Stimulation for Phantom Limb Pain: A Functional Magnetic Resonance Imaging Study: Technical Case Report

Neurosurgery ◽  
2001 ◽  
Vol 48 (3) ◽  
pp. 681-688 ◽  
Author(s):  
Franck-Emmanuel Roux ◽  
Danielle Ibarrola ◽  
Yves Lazorthes ◽  
Isabelle Berry
Keyword(s):  
Motor Cortex ◽  
Phantom Limb Pain ◽  
Phantom Limb ◽  
Electrode Placement ◽  
Control Mechanisms ◽  
Motor Cortex Stimulation ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging ◽  
Limb Pain ◽  
Stereotactic Device

Abstract OBJECTIVE AND IMPORTANCE Chronic motor cortex stimulation has provided satisfactory control of pain in patients with central or neuropathic trigeminal pain. We used this technique in a patient who experienced phantom limb pain. Functional magnetic resonance imaging (fMRI) was used to guide electrode placement and to assist in understanding the control mechanisms involved in phantom limb pain. CLINICAL PRESENTATION A 45-year-old man whose right arm had been amputated 2 years previously experienced phantom limb pain and phantom limb phenomena, described as the apparent possibility of moving the amputated hand voluntarily. He was treated with chronic motor cortex stimulation. INTERVENTION Data from fMRI were used pre- and postoperatively to detect shoulder and stump cortical activated areas and the “virtual” amputated hand cortical area. These sites of preoperative fMRI activation were integrated in an infrared-based frameless stereotactic device for surgical planning. Phantom limb virtual finger movement caused contralateral primary motor cortex activation. Satisfactory pain control was obtained; a 70% reduction in the phantom limb pain was achieved on a visual analog scale. Postoperatively and under chronic stimulation, inhibiting effects on the primary sensorimotor cortex as well as on the contralateral primary motor and sensitive cortices were detected by fMRI studies. CONCLUSION Chronic motor cortex stimulation can be used to relieve phantom limb pain and phantom limb phenomena. Integrated by an infrared-based frameless stereotactic device, fMRI data are useful in assisting the neurosurgeon in electrode placement for this indication. Pain control mechanisms and cortical reorganization phenomena can be studied by the use of fMRI.

Chronic Motor Cortex Stimulation for Phantom Limb Pain: Correlations between Pain Relief and Functional Imaging Studies

2001 ◽  
Vol 77 (1-4) ◽  
pp. 172-176 ◽  
Author(s):  
J.Ch. Sol ◽  
J. Casaux ◽  
F.E. Roux ◽  
J.A. Lotterie ◽  
P. Bousquet ◽  
...  
Keyword(s):  
Pain Relief ◽  
Motor Cortex ◽  
Functional Imaging ◽  
Phantom Limb Pain ◽  
Phantom Limb ◽  
Motor Cortex Stimulation ◽  
Imaging Studies ◽  
Limb Pain

scholarly journals Mechanistic analysis of motor cortex stimulation for phantom limb pain

PAIN RESEARCH ◽  
2008 ◽  
Vol 23 (1) ◽  
pp. 27-34 ◽  
Author(s):  
Takufumi Yanagisawa ◽  
Youichi Saitoh ◽  
Masayuki Hirata ◽  
Okito Yamashita ◽  
Yukiyasu Kamitani ◽  
...  
Keyword(s):  
Motor Cortex ◽  
Phantom Limb Pain ◽  
Phantom Limb ◽  
Motor Cortex Stimulation ◽  
Limb Pain ◽  
Mechanistic Analysis

Effects of Combined and Alone Transcranial Motor Cortex Stimulation and Mirror Therapy in Phantom Limb Pain: A Randomized Factorial Trial

2021 ◽  
pp. 154596832110175
Author(s):  
Muhammed Enes Gunduz ◽  
Kevin Pacheco-Barrios ◽  
Camila Bonin Pinto ◽  
Dante Duarte ◽  
Faddi Ghassan Saleh Vélez ◽  
...  
Keyword(s):  
Motor Cortex ◽  
Lower Limb ◽  
Phantom Limb Pain ◽  
Phantom Limb ◽  
Limb Amputation ◽  
Motor Cortex Stimulation ◽  
Mirror Therapy ◽  
Limb Pain ◽  
Factorial Trial ◽  
Motor Cortex Plasticity

Phantom limb pain (PLP) is a frequent complication in amputees, which is often refractory to treatments. We aim to assess in a factorial trial the effects of transcranial direct current stimulation (tDCS) and mirror therapy (MT) in patients with traumatic lower limb amputation; and whether the motor cortex plasticity changes drive these results. In this large randomized, blinded, 2-site, sham-controlled, 2 × 2 factorial trial, 112 participants with traumatic lower limb amputation were randomized into treatment groups. The interventions were active or covered MT for 4 weeks (20 sessions, 15 minutes each) combined with 2 weeks of either active or sham tDCS (10 sessions, 20 minutes each) applied to the contralateral primary motor cortex. The primary outcome was PLP changes on the visual analogue scale at the end of interventions (4 weeks). Motor cortex excitability and cortical mapping were assessed by transcranial magnetic stimulation (TMS). We found no interaction between tDCS and MT groups ( F = 1.90, P = .13). In the adjusted models, there was a main effect of active tDCS compared to sham tDCS (beta coefficient = −0.99, P = .04) on phantom pain. The overall effect size was 1.19 (95% confidence interval: 0.90, 1.47). No changes in depression and anxiety were found. TDCS intervention was associated with increased intracortical inhibition (coefficient = 0.96, P = .02) and facilitation (coefficient = 2.03, P = .03) as well as a posterolateral shift of the center of gravity in the affected hemisphere. MT induced no motor cortex plasticity changes assessed by TMS. These findings indicate that transcranial motor cortex stimulation might be an affordable and beneficial PLP treatment modality.

A systematic review on the treatment of phantom limb pain with spinal cord stimulation

2017 ◽  
Vol 7 (1) ◽  
pp. 59-69 ◽  
Author(s):  
Rohit Aiyer ◽  
Robert L Barkin ◽  
Anurag Bhatia ◽  
Semih Gungor
Keyword(s):  
Systematic Review ◽  
Spinal Cord ◽  
Spinal Cord Stimulation ◽  
Phantom Limb Pain ◽  
Phantom Limb ◽  
Limb Pain
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