Late Sequelae of Cerebrovascular Disease in African-Americans: Vascular Dementia

1998 ◽  
pp. 188-197 ◽  
Author(s):  
P.B. Gorelick ◽  
P. Griffith
Keyword(s):  
African Americans ◽  
Cerebrovascular Disease ◽  
Vascular Dementia ◽  
Late Sequelae

The Spectrum of Cerebrovascular Disease and Associated Cognitive Decline

2019 ◽  
pp. 574-599
Author(s):  
Victoria J. Williams ◽  
Steven E. Arnold ◽  
David H. Salat
Keyword(s):  
Risk Factors ◽  
Cognitive Impairment ◽  
Cerebrovascular Disease ◽  
Cognitive Decline ◽  
Vascular Dementia ◽  
Structure And Function ◽  
Vascular Risk Factors ◽  
Vascular Health ◽  
Vascular Risk ◽  
And Function

Throughout the lifespan, common variations in systemic health and illness contribute to alterations in vasculature structure and function throughout the body, significantly increasing risk for cardiovascular and cerebrovascular disease (CVD). CVD is a prevalent cause of mortality in late life; it also promotes brain alterations, contributing to cognitive decline and, when severe, vascular dementia. Even prior to diseased states, individual variation in CVD risk is associated with structural and functional brain alterations. Yet, how cumulative asymptomatic alterations in vessel structure and function contribute to more subtle changes in brain tissue integrity and function that emerge in late life is unclear. Finally, vascular risk factors are associated with the clinical progression of neurodegenerative diseases such as Alzheimer’s disease (AD); however, recent theory posits that vascular degeneration may serve a contributory role in these conditions. This chapter reviews how lifespan changes in vascular health contribute to degenerative changes in neural tissue and the subsequent development of cognitive impairment and/or vascular dementia. It first discusses associations between vascular risk factors and cognition and also how declining vascular health may lead to cognitive impairment and dementia. Next, it identifies basic aspects of cerebrovascular anatomy and physiology sustaining tissue health and discusses how vulnerabilities of this system contribute to neurodegenerative changes. Finally, it reviews evidence of vascular contributions to AD and presents ideas for future research to better understand the full spectrum of cerebrovascular contributions to brain aging, cognitive decline, and dementia.

APOE genotype in cerebrovascular disease and vascular dementia

2002 ◽  
Vol 203-204 ◽  
pp. 173-176 ◽  
Author(s):  
A Frank ◽  
E Dı́ez-Tejedor ◽  
M.J Bullido ◽  
F Valdivieso ◽  
P Barreiro
Keyword(s):  
Cerebrovascular Disease ◽  
Vascular Dementia ◽  
Apoe Genotype

CT and MRI findings among African-Americans with Alzheimer's disease, vascular dementia, and stroke without dementia

Neurology ◽  
1995 ◽  
Vol 45 (8) ◽  
pp. 1456-1461 ◽  
Author(s):  
D. Charletta ◽  
P.B. Gorelick ◽  
T.J. Dollear ◽  
S. Freels ◽  
Y. Harris
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
African Americans ◽  
Vascular Dementia ◽  
Mri Findings ◽  
Ct And Mri

scholarly journals Effect of Thrombin Inhibition in Vascular Dementia and Silent Cerebrovascular Disease

Stroke ◽  
1999 ◽  
Vol 30 (5) ◽  
pp. 1033-1037 ◽  
Author(s):  
Kazuomi Kario ◽  
Takefumi Matsuo ◽  
Satoshi Hoshide ◽  
Yuji Umeda ◽  
Kazuyuki Shimada
Keyword(s):  
Cerebrovascular Disease ◽  
Vascular Dementia ◽  
Thrombin Inhibition

scholarly journals Lifetime discrimination burden, racial discrimination, and subclinical cerebrovascular disease among African Americans.

2019 ◽  
Vol 38 (1) ◽  
pp. 63-74 ◽  
Author(s):  
Danielle L. Beatty Moody ◽  
Antione D. Taylor ◽  
Daniel K. Leibel ◽  
Elias Al-Najjar ◽  
Leslie I. Katzel ◽  
...  
Keyword(s):  
African Americans ◽  
Cerebrovascular Disease ◽  
Racial Discrimination
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