Adjuvant Radiotherapy following Radical Prostatectomy

2000 ◽  
pp. 145-151
Author(s):  
T. Wiegel
Keyword(s):  
Radical Prostatectomy ◽  
Adjuvant Radiotherapy

Adjuvant radiotherapy in patients post radical prostatectomy with tumor extending through capsule or positive seminal vesicles

Urology ◽  
1992 ◽  
Vol 39 (1) ◽  
pp. 59-62 ◽  
Author(s):  
Avi Stein ◽  
Jean B. Dekernion ◽  
Frederick Dorey ◽  
Robert B. Smith
Keyword(s):  
Radical Prostatectomy ◽  
Adjuvant Radiotherapy ◽  
Seminal Vesicles

Radiotherapy after Prostatectomy

2002 ◽  
Vol 88 (6) ◽  
pp. 445-452 ◽  
Author(s):  
Giuseppe Sanguineti ◽  
Paola Franzone ◽  
Laura Culp ◽  
Michela Marcenaro ◽  
Salvina Barra ◽  
...  
Keyword(s):  
High Risk ◽  
Radical Prostatectomy ◽  
Adjuvant Radiotherapy ◽  
Potential Role ◽  
Specific Antigen ◽  
Salvage Treatment ◽  
Salvage Radiotherapy ◽  
Risk Of Failure

Aims and background The role of radiotherapy after prostatectomy is controversial. This paper tries to give some guidelines for everyday practice through an analysis of literature data. Methods The potential role of radiotherapy in the adjuvant and salvage setting is discussed. We also report and interpret available literature data for both settings. Results As regards an increase in or detectable prostate-specific antigen (PSA) after radical prostatectomy, about 40–50% of patients are rendered bNED with local salvage radiotherapy, but only 10–50% are long-term (5 years) biochemically controlled. A timely salvage treatment is crucial to optimize control probability. As regards adjuvant radiotherapy for undetectable postoperative PSA in patients at high risk of failure as judged on pathology, results are more encouraging. Recent data report bNED rates ≥70% at 5 years. Conclusions Although results are far from satisfactory, salvage radiotherapy should be considered for every patient with an increased or detectable PSA after surgery. Adjuvant radiotherapy seems preferable to salvage radiotherapy for patients at high (>30%) risk of failure.

High Gleason grade carcinoma at a positive surgical margin predicts biochemical failure after radical prostatectomy and may guide adjuvant radiotherapy

2011 ◽  
Vol 109 (12) ◽  
pp. 1794-1800 ◽  
Author(s):  
Richard Savdie ◽  
Lisa G. Horvath ◽  
Ruth Pe Benito ◽  
Krishan K. Rasiah ◽  
Anne-Maree Haynes ◽  
...  
Keyword(s):  
Radical Prostatectomy ◽  
Adjuvant Radiotherapy ◽  
Surgical Margin ◽  
Biochemical Failure ◽  
Positive Surgical Margin ◽  
Gleason Grade
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