IORT for Early Breast Cancer: A Report on Long-Term Results

1997 ◽  
pp. 126-130 ◽  
Author(s):  
H.W. Merrick, III ◽  
J.A. Battle ◽  
B.J. Padgett ◽  
R.R. Dobelbower, Jr.
Keyword(s):  
Breast Cancer ◽  
Early Breast Cancer ◽  
Long Term Results

scholarly journals Are breast conservation and mastectomy equally effective in the treatment of young women with early breast cancer? Long-term results of a population-based cohort of 1,451 patients aged ≤40 years

2010 ◽  
Vol 127 (1) ◽  
pp. 207-215 ◽  
Author(s):  
Maurice J. C. van der Sangen ◽  
Fenneke M. M. van de Wiel ◽  
Philip M. P. Poortmans ◽  
Vivianne C. G. Tjan-Heijnen ◽  
Grard A. P. Nieuwenhuijzen ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Early Breast Cancer ◽  
Young Women ◽  
Breast Conservation ◽  
Population Based ◽  
Long Term Results

Accelerated Partial-Breast Irradiation Compared With Whole-Breast Irradiation for Early Breast Cancer: Long-Term Results of the Randomized Phase III APBI-IMRT-Florence Trial

2020 ◽  
Vol 38 (35) ◽  
pp. 4175-4183 ◽  
Author(s):  
Icro Meattini ◽  
Livia Marrazzo ◽  
Calogero Saieva ◽  
Isacco Desideri ◽  
Vieri Scotti ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Early Breast Cancer ◽  
Phase Iii ◽  
Accelerated Partial Breast Irradiation ◽  
Long Term Results ◽  
Partial Breast Irradiation ◽  
Whole Breast Irradiation ◽  
Breast Irradiation ◽  
Once Daily

PURPOSE To report the long-term results of external-beam accelerated partial-breast irradiation (APBI) intensity-modulated radiation therapy (IMRT) Florence phase III trial comparing whole-breast irradiation (WBI) to APBI in early-stage breast cancer. PATIENTS AND METHODS The primary end point was to determine the 5-year difference in ipsilateral breast tumor recurrence (IBTR) between 30 Gy in 5 once-daily fractions (APBI arm) and 50 Gy in 25 fractions with a tumor bed boost (WBI arm) after breast-conserving surgery. RESULTS Five hundred twenty patients, more than 90% of whom had characteristics associated with low recurrence risk, were randomly assigned (WBI, n = 260; APBI, n = 260) between 2005 and 2013. Median follow-up was 10.7 years. The 10-year cumulative incidence of IBTR was 2.5% (n = 6) in the WBI and 3.7% (n = 9) in the APBI arm (hazard ratio [HR], 1.56; 95% CI, 0.55 to 4.37; P = .40). Overall survival at 10 years was 91.9% in both arms (HR, 0.95; 95% CI, 0.50 to 1.79; P = .86). Breast cancer–specific survival at 10 years was 96.7% in the WBI and 97.8% in the APBI arm (HR, 0.65; 95% CI, 0.21 to 1.99; P = .45). The APBI arm showed significantly less acute toxicity ( P = .0001) and late toxicity ( P = .0001) and improved cosmetic outcome as evaluated by both physician ( P = .0001) and patient ( P = .0001). CONCLUSION The 10-year cumulative IBTR incidence in early breast cancer treated with external APBI using IMRT technique in 5 once-daily fractions is low and not different from that after WBI. Acute and late treatment-related toxicity and cosmesis outcomes were significantly in favor of APBI.

Single center long term results from the randomized phase-3 TARGIT-A trial comparing intraoperative (IORT) and whole-breast radiation therapy (WBRT) for early breast cancer.

2018 ◽  
Vol 36 (15_suppl) ◽  
pp. e12616-e12616 ◽  
Author(s):  
Yasser Abo-Madyan ◽  
Grit Welzel ◽  
Elena Sperk ◽  
Christian Neumaier ◽  
Anke Keller ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Radiation Therapy ◽  
Early Breast Cancer ◽  
Long Term Results ◽  
Single Center ◽  
Phase 3

Age of menopause among women who remain premenopausal following treatment for early breast cancer: Long-term results from International Breast Cancer Study Group Trials V and VI

2007 ◽  
Vol 43 (11) ◽  
pp. 1646-1653 ◽  
Author(s):  
Ann Partridge ◽  
Shari Gelber ◽  
Richard D. Gelber ◽  
Monica Castiglione-Gertsch ◽  
Aron Goldhirsch ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Early Breast Cancer ◽  
Long Term Results ◽  
Study Group ◽  
Cancer Study ◽  
Cancer Study Group ◽  
Breast Cancer Study

scholarly journals Long-term results of combined treatment of patients with early breast cancer after conserving therapy

2016 ◽  
Vol 3 ◽  
pp. 164-169
Author(s):  
Piotr Kędzierawski ◽  
Izabela Ciepiela ◽  
Agnieszka Florek ◽  
Artur Bocian ◽  
Paweł Macek ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Early Breast Cancer ◽  
Combined Treatment ◽  
Long Term Results

PD-0216 LONG TERM RESULTS OF A RANDOMIZED STUDY OF IORT VERSUS EXTERNAL BEAM BOOST IN EARLY BREAST CANCER PATIENTS

2012 ◽  
Vol 103 ◽  
pp. S83-S84
Author(s):  
A. Ciabattoni ◽  
S. Drago ◽  
G.B. Grassi ◽  
A. De Gregorio ◽  
F. Felicioni ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Early Breast Cancer ◽  
Randomized Study ◽  
Long Term Results ◽  
External Beam ◽  
Breast Cancer Patients

Preoperative radio-chemotherapy in early breast cancer patients: Long-term results of a phase II trial

2012 ◽  
Vol 102 (1) ◽  
pp. 82-88 ◽  
Author(s):  
Marc A. Bollet ◽  
Lisa Belin ◽  
Fabien Reyal ◽  
François Campana ◽  
Rémi Dendale ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Early Breast Cancer ◽  
Phase Ii ◽  
Phase Ii Trial ◽  
Long Term Results ◽  
Breast Cancer Patients ◽  
Radio Chemotherapy
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