Expression of Membrane Melatonin Receptor mRNA in Rat Thymus and Spleen

1997 ◽  
pp. 36-42 ◽  
Author(s):  
D. Pozo ◽  
M. Delgado ◽  
J.R. Calvo ◽  
A. Garcia-PergaNeda ◽  
J.M. Guerrero
Keyword(s):  
Melatonin Receptor ◽  
Receptor Mrna

Melatonin receptor mRNA localization and rhythmicity in the retina of the domestic chick, Gallus domesticus

2002 ◽  
Vol 19 (3) ◽  
pp. 265-274 ◽  
Author(s):  
ARJUN K. NATESAN ◽  
VINCENT M. CASSONE
Keyword(s):  
Ganglion Cell ◽  
Ganglion Cell Layer ◽  
Cell Layer ◽  
Rnase Protection Assay ◽  
Inner Nuclear Layer ◽  
Constant Darkness ◽  
Melatonin Receptor ◽  
Rnase Protection ◽  
Receptor Mrna ◽  
Lower Amplitude

The indoleamine hormone melatonin is synthesized and released by photoreceptors during the night within the chick retina, and confers timing information to modulate retinal physiology. Three subtypes of melatonin receptor with nearly identical pharmacological profiles have been described in chickens and are present in the retina. In this study, the spatial localization and temporal pattern of the mRNA for each of these receptors within the retina are described. The localization and rhythmicity of receptor mRNA were analyzed using in situ hybridization and RNase protection assay, respectively, with probes against specific nucleotide sequences encoding these receptors. Mel1A and Mel1C receptor mRNA have similar patterns of expression, primarily in the inner segments of photoreceptors, vitread portion of the inner nuclear layer, and in the retinal ganglion cell layer. Mel1B receptor mRNA is expressed at higher levels in the retina, with expression in photoreceptors, throughout the inner nuclear layer, and in the ganglion cell layer. Mel1A receptor mRNA is rhythmic in both light:dark (LD) cycles and in constant darkness (DD); Mel1A peaks during midday and mid-subjective day, respectively. Mel1C receptor mRNA is also rhythmically expressed in LD, but with a lower amplitude, such that transcript is high during the day and low during the night. In DD, Mel1C rhythms become 180 deg out of phase with a slight increase at night. Mel1B mRNA expression was highly variable and arrhythmic.

Melatonin receptor mRNA expression in Xenopus oocytes: Inhibition of G-protein-activated response

1991 ◽  
Vol 124 (2) ◽  
pp. 242-245 ◽  
Author(s):  
S.P. Fraser ◽  
P. Barrett ◽  
M.B.A. Djamgoz ◽  
P.J. Morgan
Keyword(s):  
Mrna Expression ◽  
G Protein ◽  
Xenopus Oocytes ◽  
Melatonin Receptor ◽  
Receptor Mrna

Developmental expression of ‘RZRβ, a putative nuclear-melatonin receptor’ mRNA in the suprachiasmatic nucleus of the rat

1996 ◽  
Vol 217 (1) ◽  
pp. 17-20
Author(s):  
Hwan Tae Park ◽  
Sun Yong Baek ◽  
Bong Seon Kim ◽  
Jae Bong Kim ◽  
Jin Jeong Kim
Keyword(s):  
Suprachiasmatic Nucleus ◽  
Developmental Expression ◽  
Melatonin Receptor ◽  
Receptor Mrna
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