Hereditary Papillary Renal Carcinoma: Pathology and Pathogenesis

1999 ◽  
pp. 11-27 ◽  
Author(s):  
L. Schmidt ◽  
I. Lubensky ◽  
W.M. Linehan ◽  
B. Zbar
Keyword(s):  
Renal Carcinoma ◽  
Hereditary Papillary Renal Carcinoma

Novel germline c-MET mutation in a family with hereditary papillary renal carcinoma

2012 ◽  
Vol 11 (3) ◽  
pp. 535-537 ◽  
Author(s):  
Karin A. W. Wadt ◽  
Anne-Marie Gerdes ◽  
Thomas V. O. Hansen ◽  
Birgitte G. Toft ◽  
Lennart Friis-Hansen ◽  
...  
Keyword(s):  
Renal Carcinoma ◽  
Hereditary Papillary Renal Carcinoma

EARLY ONSET HEREDITARY PAPILLARY RENAL CARCINOMA: GERMLINE MISSENSE MUTATIONS IN THE TYROSINE KINASE DOMAIN OF THE MET PROTO-ONCOGENE

2004 ◽  
Vol 172 (4 Part 1) ◽  
pp. 1256-1261 ◽  
Author(s):  
LAURA S. SCHMIDT ◽  
MICHAEL L. NICKERSON ◽  
DEBORA ANGELONI ◽  
GLADYS M. GLENN ◽  
McCLELLAN M. WALTHER ◽  
...  
Keyword(s):  
Tyrosine Kinase ◽  
Early Onset ◽  
Renal Carcinoma ◽  
Kinase Domain ◽  
Tyrosine Kinase Domain ◽  
Missense Mutations ◽  
Hereditary Papillary Renal Carcinoma

scholarly journals Hereditary Papillary Renal Carcinoma Type I

2004 ◽  
Vol 4 (8) ◽  
pp. 855-868 ◽  
Author(s):  
Pathirage Dharmawardana ◽  
Alessio Giubellino ◽  
Donald Bottaro
Keyword(s):  
Renal Carcinoma ◽  
Type I ◽  
Hereditary Papillary Renal Carcinoma

Common pattern of unusual chromosome abnormalities in hereditary papillary renal carcinoma

2006 ◽  
Vol 164 (2) ◽  
pp. 142-147 ◽  
Author(s):  
Esther Prat ◽  
Marta Bernués ◽  
Javier del Rey ◽  
Jordi Camps ◽  
Immaculada Ponsa ◽  
...  
Keyword(s):  
Renal Carcinoma ◽  
Chromosome Abnormalities ◽  
Common Pattern ◽  
Unusual Chromosome ◽  
Hereditary Papillary Renal Carcinoma

Hereditary Papillary Renal Carcinoma

2013 ◽  
pp. 312-312
Author(s):  
Claudia E. Rübe ◽  
Bernadine R. Donahue ◽  
Jay S. Cooper ◽  
Caspian Oliai ◽  
Yan Yu ◽  
...  
Keyword(s):  
Renal Carcinoma ◽  
Hereditary Papillary Renal Carcinoma

scholarly journals Familial Renal Cancer: Molecular Genetics and Surgical Management

2011 ◽  
Vol 2011 ◽  
pp. 1-11 ◽  
Author(s):  
Glen W. Barrisford ◽  
Eric A. Singer ◽  
Inger L. Rosner ◽  
W. Marston Linehan ◽  
Gennady Bratslavsky
Keyword(s):  
Surgical Management ◽  
Kidney Cancer ◽  
Renal Cancer ◽  
Genetic Basis ◽  
Renal Carcinoma ◽  
Systemic Disease ◽  
Genetic Alterations ◽  
Response To Therapy ◽  
Von Hippel Lindau ◽  
Hereditary Papillary Renal Carcinoma

Familial renal cancer (FRC) is a heterogeneous disorder comprised of a variety of subtypes. Each subtype is known to have unique histologic features, genetic alterations, and response to therapy. Through the study of families affected by hereditary forms of kidney cancer, insights into the genetic basis of this disease have been identified. This has resulted in the elucidation of a number of kidney cancer gene pathways. Study of these pathways has led to the development of novel targeted molecular treatments for patients affected by systemic disease. As a result, the treatments for families affected by von Hippel-Lindau (VHL), hereditary papillary renal carcinoma (HPRC), hereditary leiomyomatosis renal cell carcinoma (HLRCC), and Birt-Hogg-Dubé (BHD) are rapidly changing. We review the genetics and contemporary surgical management of familial forms of kidney cancer.

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