Effect of Antiproteinuric Treatment on the Lipid Profile in Nondiabetic Renal Disease

1997 ◽  
pp. 88-96 ◽  
Author(s):  
G. Navis ◽  
H. Buter ◽  
P.E. de Jong ◽  
R.P.F. Dullaart ◽  
D. de Zeeuw
Keyword(s):  
Renal Disease ◽  
Lipid Profile

scholarly journals ASSESSMENT OF LIPID PROFILE AMONG PATIENTS OF NON-DIABETIC CHRONIC KIDNEY DISEASE AT TERTIARY CARE CENTRE

2019 ◽  
Vol 3 (11) ◽  
Author(s):  
Dr Bakul Gupta
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Renal Disease ◽  
Lipid Profile ◽  
Chronic Renal Disease ◽  
Tertiary Care ◽  
Study Participant ◽  
P Value ◽  
Additional Risk Factor ◽  
Study Participants

Background: Various studies have shown the association between dyslipidemia and cardio-vascular risk among patients of chronic renal disease but the association non-significant than patients with normal renal function. There was lack of evidence exists because patients with chronic renal disease were excluded from the major clinical studies where the association with that target dyslipidemia treatment was being evaluated Material & Methods: The present prospective study was conducted among the patients of Chronic Kidney Disease above 18 years of age and diagnosed on the basis of history, detailed clinical examination, and biochemical and sonological examination based upon National Kidney Foundation (NKF) criteria were enrolled into the study. Clearance from hospital ethics committee was taken before start of study. Written informed consent was taken from each study participant. Results:  In the present study out of total study participants of chronic kidney disease 46% were in the 3rd stage of CKD, 38% were in the 4th stage of CKD and 16% were in the 5th stage of CKD. Out of total study participants of chronic kidney disease, 82% were managed by conservative treatment and 18% were being managed by hemodialysis. Out of total study participants of chronic kidney disease, 38% had normal lipid profile while 62% patients had dyslipidemia. We found statistically significant (p value < 0.05) association between dyslipidemia and hemodialysis and association between dyslipidemia and stages of chronic kidney disease was statistically non- significant (p value > 0.05). Conclusion:  We concluded from the present study that dyslipidemia is significantly associated as an additional risk factor in patients of Chronic Kidney Disease. We found significant association of hemodialysis with abnormal lipid profile. Key words: Chronic kidney disease, dyslipidemia, hemodialysis.

scholarly journals Serum lipid profile of Nigerian diabetics with end stage renal disease

2006 ◽  
Vol 24 (4) ◽  
Author(s):  
Emmanuel I Agaba ◽  
Mary Duguru ◽  
Patricia A Agaba ◽  
Dorcas Angbazo
Keyword(s):  
Renal Disease ◽  
Lipid Profile ◽  
End Stage Renal Disease ◽  
Serum Lipid ◽  
Serum Lipid Profile ◽  
Stage Renal Disease ◽  
End Stage

scholarly journals Assessment of thyroid dysfunction, dyslipidemia and oxidative stress in hypertensive end stage chronic renal disease patients in a teaching hospital in Western Uttar Pradesh

2019 ◽  
Vol 10 (5) ◽  
pp. 13-18
Author(s):  
Poonam Kachhawa ◽  
Vivek Sinha
Keyword(s):  
Oxidative Stress ◽  
Cardiovascular Disease ◽  
Superoxide Dismutase ◽  
Renal Disease ◽  
Lipid Profile ◽  
Thyroid Dysfunction ◽  
Chronic Renal Disease ◽  
Economic Output ◽  
End Stage ◽  
And Oxidative Stress

Background: CKD is a serious health problem in worldwide. In developing nation, CKD has severe implication on health and economic output. The rapid increase of common risk factors such as hypertension (HTN), obesity and type 2 diabetes will result in greater and more burdens to developing country. There are many complications associated with CKD including thyroid dysfunction, dyslipidemia,hypertension and cardiovascular disease (CVD).It is generally seen that patients suffering from CKD are at high risk of cardiovascular disease. Aims and Objectives: The purpose of the study was to evaluate the diagnostic screening of thyroid dysfunction, dyslipidemia and oxidative stress in hypertensive end stage chronic renal disease patients. Materials and Methods: Thyroid status, Lipid profile, serum Urea, serum Creatinine, serum Uric acid, serum electrolyte, Catalase,Malondialdehyde (MDA) and Superoxide dismutase (SOD) were assayed in 160 subjects in which 80 patients of CKD were having hypertension and 80 healthy controls. Results: In our study, we found statistical significantly increased level of (p<0.001) of malondialdehyde (MDA) and significantly decreased level (p<0.001) of Catalase and Superoxide dismutase (SOD).There was found significantly increased level (p<0.001) of TSH in CKD associated with hypertension patients.We also found deranged lipid profile and renal functions in CKD associated with hypertension patients as compared to controls. Conclusion: In the present study, we arrived at conclusion that dyslipidemia and thyroid dysfunction is very common in CKD patients. Our study revealed that there was significant association between thyroid dysfunction and CKD progression and dyslipidemia. The antioxidant status is assessed through changes in antioxidant enzymatic activity in patients of CKD with hypertensive and data provide evidence of blood pressure modulation by measurable oxidative stress–related parameters.

scholarly journals IMPACT OF DURATION OF HEMODIALYSIS ON LIPID PROFILE IN END STAGE RENAL DISEASE PATIENTS RECEIVING HEMODIALYSIS.

2020 ◽  
Vol 27 (06) ◽  
pp. 1230-1236
Author(s):  
Sadia Rehman ◽  
Santosh Kumar ◽  
Fatima Mehboob ◽  
Fatima Rehman ◽  
Syed Hidayat Ali ◽  
...  
Keyword(s):  
Renal Disease ◽  
Lipid Profile ◽  
End Stage Renal Disease ◽  
Serum Triglyceride ◽  
Hemodialysis Patients ◽  
Maintenance Hemodialysis ◽  
Healthy Controls ◽  
Stage Renal Disease ◽  
End Stage ◽  
Esrd Patients

End Stage Renal Disease (ESRD) patients receiving hemodialysis are at a higher risk of developing dyslipidemia which is undoubtedly a predisposing factor of cardiac related disease in these patients. Objectives: To assess serum lipid profile in subjects having end stage renal disease and receiving maintenance hemodialysis and to compare it with normal healthy controls and also to assess the effects of duration of hemodialysis on the lipid profile. Study Design: A case-control study. Setting: Executed in the Nephrology Department of JPMC. Period: January 2018 to January 2019. Material and Methods: Blood samples were obtained from a total of 90 subjects. Subjects were stratified into 3 groups including cases of ESRD receiving maintenance hemodialysis and matched healthy controls. Analysis for serum triglyceride, serum VLDL, total cholesterol, LDL and HDL was done. Results: A significant rise in serum triglyceride content and total serum cholesterol of hemodialysis patients (p < 0.01) was detected as compared to healthy controls. A statistically significant decrease was found in serum HDL level (p < 0.01) in hemodialysis patients in comparison to healthy controls. The impact of the hemodialysis duration was found to deteriorate the lipid profile of patients having longer duration of hemodialysis. Conclusion: Dyslipidemia was found to be evident in hemodialysis patients. The duration of hemodialysis sessions was found to affect the lipid profile of ESRD patients, which may play a role in higher incidence of atherosclerotic related cardiac events among these patients.

scholarly journals Comparison of Lipid Profile Among the Different Stages of Chronic Kidney Disease in Children

KYAMC Journal ◽  
2019 ◽  
Vol 10 (3) ◽  
pp. 137-142
Author(s):  
Muhammad Mozammel Haque ◽  
Mosammat Afroza Jinnat ◽  
Shafi Ahmed ◽  
Ranjit Ranjan Roy ◽  
Mohammad Akteruzzaman ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Renal Disease ◽  
Lipid Profile ◽  
End Stage Renal Disease ◽  
Obstructive Uropathy ◽  
Group I ◽  
Ckd Stage ◽  
Stage Renal Disease ◽  
End Stage

Background: Chronic Kidney Disease (CKD) is associated with significantly increased morbidity and mortality. Children with (CKD)/End stage renal disease (ESRD) exhibit various co-morbidities, including dyslipidemia. Hypertriglyceridemia is inversely correlated with renal function. Children with advanced chronic kidney disease or end stage renal disease developed atherosclerosis and cardiovascular disease. Objectives: To measure the lipid profile in kidney disease and comparison of lipid profile among the different stages of CKD. Materials and Methods: A cross sectional analytic study to measure and compare lipid profile in fifty children with different stages of chronic kidney disease during January 2016 to June 2016 by purposive sampling technique and divided into two groups, Children with CKD stage iii and iv included in Group I and CKD stage V and V(D) included in Group II. Results: Out of Fifty children with CKD, 28(56%) were male and 22 (44%) male, 30(60%) were of11-15 year age group and 32(64%) were from rural area and 18(36%) from urban area. The etiology of CKD in two groups glomerulonephritis were 14(28%), obstructive uropathy 15 (30%), hypoplasia/dysplasia 9(18%), polycystic kidney disease 9(18%) and acute kidney injury 3(6%). All the cases were anemic, 26(52%) were hypertensive and 20(40%) had osteodystrophy. Conclusion: Dyslipidemia specially hypertriglyceridemia is common in children with CKD. Hypertriglyceridemia is inversely related to severity of CKD stages. KYAMC Journal Vol. 10, No.-3, October 2019, Page 137-142

scholarly journals Investigation of factors related to N-terminal pro-B type natriuretic peptide levels in hemodialysis patients; a single center study

2019 ◽  
Vol 9 (1) ◽  
pp. e05-e05
Author(s):  
Farbod Bonakdar ◽  
Pegah Noorshargh ◽  
Parin Hedayati ◽  
Hamid Nasri
Keyword(s):  
Renal Disease ◽  
Lipid Profile ◽  
Natriuretic Peptide ◽  
Demographic Data ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Serum Triglyceride ◽  
Hemodialysis Patients ◽  
Stage Renal Disease ◽  
Esrd Patients

Introduction: Introduction: N-terminal pro-B type natriuretic peptide (NT-proBNP) can be used to diagnose cardiac and renal disease. The association of NT-pro BNP with demographic, clinical and biochemical factors in hemodialysis is unclear. Objectives: This study aimed to examine association of NT-pro BNP and mentioned factors in hemodialysis patients. Patients and Methods: This study was conducted on 78 end-stage renal disease (ESRD) patients under hemodialysis. Demographic data, lipid profile and electrolytes were recorded. NT-proBNP was checked simultaneously and its association with mentioned factors were assessed. Results: The average NT-pro BNP level was 890.52±700.87 pg/mL (range: 0.1-3343 pg/mL). Serum level of NT-pro BNP was statistically in association with total cholesterol (P=0.002; r=-0.348), low density lipoprotein (LDL) (P=0.09; r= -0.292), high density lipoprotein (HDL) (P=0.06; r=-0.310) and serum triglyceride (P=0.018; r=-0.269) while having a direct relationship with serum ferritin (P=0.022; r=0.274), alkaline phosphatase (ALP) (P=0.048; r=0.224) and duration of hemodialysis (P=0.005; r=0.321). Conclusion: Lipid profile and ferritin are associated with NT-pro BNP levels. This can reflect possible prognostic role of NT-proBNP among ESRD patients on hemodialysis.

AUSDIAB * RENAL STUDY – EARLY INDICATORS OF RENAL DISEASE

Nephrology ◽  
2000 ◽  
Vol 5 (3) ◽  
pp. A93-A93
Author(s):  
Sj Chadban ◽  
P Kerr ◽  
E Briganti ◽  
D Dunstan ◽  
M De Courten ◽  
...  
Keyword(s):  
Renal Disease ◽  
Early Indicators
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