Dietary Intake of Long-Chain Polyunsaturated Fatty Acids during the Paleolithic

Author(s):  
S.B. Eaton ◽  
S.B. Eaton III ◽  
A.J. Sinclair ◽  
L. Cordain ◽  
N.J. Mann
2014 ◽  
Vol 10 (9) ◽  
pp. 20140623 ◽  
Author(s):  
Md. Moshiur Rahman ◽  
Clelia Gasparini ◽  
Giovanni M. Turchini ◽  
Jonathan P. Evans

The health benefits of diets containing rich sources of long-chain omega-3 polyunsaturated fatty acids (n-3 LC-PUFA) are well documented and include reductions in the risk of several diseases typical of Western societies. The dietary intake of n-3 LC-PUFA has also been linked to fertility, and there is abundant evidence that a range of ejaculate traits linked to fertility in humans, livestock and other animals depend on an adequate intake of n-3 LC-PUFA from dietary sources. However, relatively few studies have explored how n-3 LC-PUFA influence reproductive fitness, particularly in the context of sexual selection. Here, we show that experimental reduction in the level of n-3 LC-PUFA in the diet of guppies ( Poecilia reticulata ) depresses a male's share of paternity when sperm compete for fertilization, confirming that the currently observed trend for reduced n-3 LC-PUFA in western diets has important implications for individual reproductive fitness.


2000 ◽  
Vol 31 (5) ◽  
pp. 540-553 ◽  
Author(s):  
Dennis R. Hoffman ◽  
Eileen E. Birch ◽  
David G. Birch ◽  
Ricardo Uauy ◽  
Yolanda S. Castañeda ◽  
...  

Nutrition ◽  
2006 ◽  
Vol 22 (1) ◽  
pp. 47-53 ◽  
Author(s):  
Peter Howe ◽  
Barbara Meyer ◽  
Sally Record ◽  
Katrine Baghurst

2021 ◽  
pp. 089033442199346
Author(s):  
Adriana V. Gaitán ◽  
JodiAnne T. Wood ◽  
Yingpeng Liu ◽  
Lipin Ji ◽  
Spyros P. Nikas ◽  
...  

Background Dietary long-chain polyunsaturated fatty acids are known to benefit infant development. After birth, human milk provides arachidonic, eicosapentaenoic, and docosahexaenoic acids to the infant. Endocannabinoids are endogenous lipid mediators derived from the long-chain polyunsaturated fatty acids. Although the roles and the mechanisms of action are not fully understood, previous researchers have suggested that endocannabinoids might play a role in infant feeding behavior. Research Aims To assess (i) maternal dietary intake of long-chain polyunsaturated fatty acids and (ii) their relationship to concentrations of fatty acids and derived endocannabinoids in human milk. Methods For this exploratory-longitudinal study, participants ( N = 24) provided dietary intake data and milk samples. Fatty acids and derived endocannabinoids: Arachidonylethanolamide, arachidonoylglycerol, docosahexaenoyl glycerol, eicosapentaenoyl ethanolamide, and eicosapenaenoyl glycerol were identified in their milk by liquid chromatography-mass spectrometry and correlations to dietary fatty acids were assessed. Results Participants were not consuming recommended amounts of docosahexaenoic acid. Significant correlations ( p ≤ .05) were only found between dietary docosahexaenoic and eicosapentaenoic acids and the concentrations of these in human milk. Moreover, only dietary docosahexaenoic acid was correlated ( p = .031) with its corresponding endocannabinoid, docosahexaenoyl glycerol. Conclusions To the best of our knowledge, this may be one of the first studies evaluating relationships between dietary long-chain polyunsaturated fatty acids and multiple endocannabinoids in human milk. Our findings suggest that endocannabinoid concentrations could be modulated by dietary precursors. Future research studies can be designed based on these data to better elucidate the roles of endocannabinoids in human milk for infant health and development.


PLoS ONE ◽  
2018 ◽  
Vol 13 (4) ◽  
pp. e0196037 ◽  
Author(s):  
Ryoji Yanai ◽  
Shang Chen ◽  
Sho-Hei Uchi ◽  
Tomoaki Nanri ◽  
Kip M. Connor ◽  
...  

Nutrition ◽  
2009 ◽  
Vol 25 (10) ◽  
pp. 1011-1019 ◽  
Author(s):  
Laura A. Colangelo ◽  
Ka He ◽  
Mary A. Whooley ◽  
Martha L. Daviglus ◽  
Kiang Liu

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