Vestibular Assessment and Ear Selection for Cochlear Implantation: The Role of Bedside Testing

2000 ◽  
pp. 168-172
Author(s):  
D.D. Backous ◽  
S.M. Quigley
Keyword(s):  
Cochlear Implantation ◽  
Bedside Testing ◽  
Vestibular Assessment ◽  
Selection For

scholarly journals Integrating additional knowledge into the estimation of graphical models

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Yunqi Bu ◽  
Johannes Lederer
Keyword(s):  
Graphical Models ◽  
Tuning Parameter ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging ◽  
Graphical Modeling ◽  
Standard Methods ◽  
Neighborhood Selection ◽  
Selection For ◽  
The Brain

Abstract Graphical models such as brain connectomes derived from functional magnetic resonance imaging (fMRI) data are considered a prime gateway to understanding network-type processes. We show, however, that standard methods for graphical modeling can fail to provide accurate graph recovery even with optimal tuning and large sample sizes. We attempt to solve this problem by leveraging information that is often readily available in practice but neglected, such as the spatial positions of the measurements. This information is incorporated into the tuning parameter of neighborhood selection, for example, in the form of pairwise distances. Our approach is computationally convenient and efficient, carries a clear Bayesian interpretation, and improves standard methods in terms of statistical stability. Applied to data about Alzheimer’s disease, our approach allows us to highlight the central role of lobes in the connectivity structure of the brain and to identify an increased connectivity within the cerebellum for Alzheimer’s patients compared to other subjects.

scholarly journals The role of steroid hormones in breast cancer stem cells

2015 ◽  
Vol 22 (6) ◽  
pp. T177-T186 ◽  
Author(s):  
Bruno M Simões ◽  
Denis G Alferez ◽  
Sacha J Howell ◽  
Robert B Clarke
Keyword(s):  
Breast Cancer ◽  
Stem Cells ◽  
Cancer Stem Cells ◽  
Steroid Hormones ◽  
Normal Mammary Gland ◽  
Breast Cancer Stem Cells ◽  
Tumor Initiating Cells ◽  
Unit Of Selection ◽  
Selection For

Breast cancer stem cells (BCSCs) are potent tumor-initiating cells in breast cancer, the most common cancer among women. BCSCs have been suggested to play a key role in tumor initiation which can lead to disease progression and formation of metastases. Moreover, BCSCs are thought to be the unit of selection for therapy-resistant clones since they survive conventional treatments, such as chemotherapy, irradiation, and hormonal therapy. The importance of the role of hormones for both normal mammary gland and breast cancer development is well established, but it was not until recently that the effects of hormones on BCSCs have been investigated. This review will discuss recent studies highlighting how ovarian steroid hormones estrogen and progesterone, as well as therapies against them, can regulate BCSC activity.

Carotenoid-based plumage colouration in red bishops (Euplectes orix) — signalling presence rather than quality?

Behaviour ◽  
2011 ◽  
Vol 148 (11-13) ◽  
pp. 1372-1392 ◽  
Author(s):  
Alice U. Edler ◽  
Thomas W.P. Friedl
Keyword(s):  
Reproductive Success ◽  
Parasite Load ◽  
Blood Parasite ◽  
Male Reproductive Success ◽  
Sexually Dimorphic ◽  
Male Quality ◽  
Plumage Colouration ◽  
Selection For ◽  
Breeding Plumage

AbstractThe role of bright plumage colouration for female choice has been the focus of research in sexual selection for many years, with several studies showing that females prefer the most elaborately ornamented males, which are often also the highest quality individuals. Here, we analysed the associations between reproductive performance and plumage, body condition and blood parasite load in the red bishop (Euplectes orix), a sexually dimorphic and polygynous weaverbird species, where males in a carotenoid-based orange-to-red breeding plumage defend territories and build many nests to which they try to attract females. Male reproductive success in terms of number of nests accepted was mainly determined by the number of nests built, but was also positively related to blood parasite load, while we found no influence of plumage characteristics. Together with previously obtained data, our results indicate that plumage characteristics in the red bishop do not affect male reproductive success and are generally not suitable to reliably indicate male quality. We suggest that the primary function of the brilliant orange-scarlet breeding plumage might be presence signalling in terms of increasing conspicuousness of breeding males to females searching for mates.

Role of Ultrasound Elastography in Patient Selection for Prostatic Artery Embolization

2021 ◽  
Author(s):  
André Moreira de Assis ◽  
Airton Mota Moreira ◽  
Francisco Cesar Carnevale ◽  
Antonio Sergio Zafred Marcelino ◽  
Alberto Azoubel Antunes ◽  
...  
Keyword(s):  
Patient Selection ◽  
Ultrasound Elastography ◽  
Artery Embolization ◽  
Prostatic Artery Embolization ◽  
Selection For ◽  
Prostatic Artery

scholarly journals Cardiologic evaluation of patients undergoing chemoterapy

2015 ◽  
Vol 82 (2) ◽  
Author(s):  
Barbara Bordoni ◽  
Stefano Urbinati ◽  
Alicia Tosoni ◽  
Graziana Labanti ◽  
Alba Brandes
Keyword(s):  
Ventricular Dysfunction ◽  
Troponin I ◽  
Coronary Spasm ◽  
Left Ventricular ◽  
Cardiac Damage ◽  
Common Risk Factors ◽  
Selection For ◽  
Chemotherapy Cardiotoxicity

Life expectancy in patients affected by cancer has recently increased because of early diagnosis and actual therapies. In recent years, Oncology and Cardiology developed a tight relationship because of common risk factors (i.e. obesity, smoking, alcool intake, etc…), and for preventing the prothrombotic status due to cancer and the potential cardiotoxicity of chemotherapy. Cardiotoxicity incidence is reported from 1% up to 70% in retrospective analyses of drug protocols, mainly representing by left ventricular dysfunction (both reversible or irreversible), but also by arrhythmias, hypertension, atrioventricular block, coronary spasm, and arterial or venous thromboembolism. The early detection of the chemoterapy induced cardiotoxicity is now mandatory and can be obtained through a proper patients selection for different treatments and a strict monitoring during the follow-up period. The role of biomarkers of early cardiac damage, mainly, troponin I and brain natriuretic peptide-BNP, has been recently challenged, and algorithms are currently available. In the present paper, we propose how to perform a cardiological evaluation of patients undergoing chemoterapy tailored by the known adverse effects of the drugs.

scholarly journals Sex differences in helping effort reveal the effect of future reproduction on cooperative behaviour in birds

2018 ◽  
Vol 285 (1885) ◽  
pp. 20181164 ◽  
Author(s):  
Philip A. Downing ◽  
Ashleigh S. Griffin ◽  
Charlie K. Cornwallis
Keyword(s):  
Sex Differences ◽  
Reproductive Success ◽  
Kin Selection ◽  
Cooperative Behaviour ◽  
The Future ◽  
Helping Behaviour ◽  
Future Reproduction ◽  
Selection For ◽  
Family Groups

The evolution of helping behaviour in species that breed cooperatively in family groups is typically attributed to kin selection alone. However, in many species, helpers go on to inherit breeding positions in their natal groups, but the extent to which this contributes to selection for helping is unclear as the future reproductive success of helpers is often unknown. To quantify the role of future reproduction in the evolution of helping, we compared the helping effort of female and male retained offspring across cooperative birds. The kin selected benefits of helping are equivalent between female and male helpers—they are equally related to the younger siblings they help raise—but the future reproductive benefits of helping differ because of sex differences in the likelihood of breeding in the natal group. We found that the sex which is more likely to breed in its natal group invests more in helping, suggesting that in addition to kin selection, helping in family groups is shaped by future reproduction.

scholarly journals Losses of female song with changes from tropical to temperate breeding in the New World blackbirds

2009 ◽  
Vol 276 (1664) ◽  
pp. 1971-1980 ◽  
Author(s):  
J. Jordan Price ◽  
Scott M. Lanyon ◽  
Kevin E. Omland
Keyword(s):  
Sexual Selection ◽  
New World ◽  
Female Song ◽  
Complex Song ◽  
Evolutionary Changes ◽  
Apparent Relationship ◽  
Song Production ◽  
Selection For ◽  
The Tropics

Birds in which both sexes produce complex songs are thought to be more common in the tropics than in temperate areas, where typically only males sing. Yet the role of phylogeny in this apparent relationship between female song and latitude has never been examined. Here, we reconstruct evolutionary changes in female song and breeding latitude in the New World blackbirds (Icteridae), a family with both temperate and tropical representatives. We provide strong evidence that members of this group have moved repeatedly from tropical to temperate breeding ranges and, furthermore, that these range shifts were associated with losses of female song more often than expected by chance. This historical perspective suggests that male-biased song production in many temperate species is the result not of sexual selection for complex song in males but of selection against such songs in females. Our results provide new insights into the differences we see today between tropical and temperate songbirds, and suggest that the role of sexual selection in the evolution of bird song might not be as simple as we think.

The role of a graded profile analysis in determining candidacy and outcome for cochlear implantation in children

1999 ◽  
Vol 49 (2) ◽  
pp. 135-142 ◽  
Author(s):  
Hamid Daya ◽  
Jane C Figueirido ◽  
Karen A Gordon ◽  
Kim Twitchell ◽  
Claudine Gysin ◽  
...  
Keyword(s):  
Cochlear Implantation ◽  
Profile Analysis

scholarly journals Greedy measurement selection for state estimation

2018 ◽  
Author(s):  
J. Nichols ◽  
Albert Cohen ◽  
Peter Binev ◽  
Olga Mula
Keyword(s):  
Hilbert Space ◽  
Differential Operator ◽  
High Dimensional ◽  
Dimensional Vector ◽  
Physical Processes ◽  
Linear Measurements ◽  
Measurement Selection ◽  
Selection For ◽  
Unknown Solution

Parametric PDEs of the general form $$ \mathcal{P}(u,a)=0 $$ are commonly used to describe many physical processes, where $\mathcal{P}$ is a differential operator, a is a high-dimensional vector of parameters and u is the unknown solution belonging to some Hilbert space V. Typically one observes m linear measurements of u(a) of the form $\ell_i(u)=\langle w_i,u \rangle$, $i=1,\dots,m$, where $\ell_i\in V'$ and $w_i$ are the Riesz representers, and we write $W_m = \text{span}\{w_1,\ldots,w_m\}$. The goal is to recover an approximation $u^*$ of u from the measurements. The solutions u(a) lie in a manifold within V which we can approximate by a linear space $V_n$, where n is of moderate dimension. The structure of the PDE ensure that for any a the solution is never too far away from $V_n$, that is, $\text{dist}(u(a),V_n)\le \varepsilon$. In this setting, the observed measurements and $V_n$ can be combined to produce an approximation $u^*$ of u up to accuracy $$ \Vert u -u^*\Vert \leq \beta^{-1}(V_n,W_m) \, \varepsilon $$ where $$ \beta(V_n,W_m) := \inf_{v\in V_n} \frac{\Vert P_{W_m}v\Vert}{\Vert v \Vert} $$ plays the role of a stability constant. For a given $V_n$, one relevant objective is to guarantee that $\beta(V_n,W_m)\geq \gamma >0$ with a number of measurements $m\geq n$ as small as possible. We present results in this direction when the measurement functionals $\ell_i$ belong to a complete dictionary.

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