Selective Aspects of Infective Endocarditis: Considerations on Diagnosis, Risk Factors, Treatment and Prophylaxis

2002 ◽  
pp. 195-202 ◽  
Author(s):  
B.J. Hartman
Keyword(s):  
Risk Factors ◽  
Infective Endocarditis

Prediabetes and diabetes are both risk factors for adverse outcomes in infective endocarditis

2018 ◽  
Vol 35 (11) ◽  
pp. 1499-1507 ◽  
Author(s):  
X.-B. Wei ◽  
Y.-H. Liu ◽  
J.-L. Huang ◽  
X.-L. Chen ◽  
D.-Q. Yu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Infective Endocarditis ◽  
Adverse Outcomes

Characteristics and Analysis of Risk Factors for Mortality in Infective Endocarditis

2006 ◽  
Vol 21 (1) ◽  
pp. 25-31 ◽  
Author(s):  
Hakan Leblebicioglu ◽  
Hava Yilmaz ◽  
Yesim Tasova ◽  
Emine Alp ◽  
Rabin Saba ◽  
...  
Keyword(s):  
Risk Factors ◽  
Infective Endocarditis

MO733RISK FACTORS FOR INFECTIVE ENDOCARDITIS IN PATIENTS RECEIVING HAEMODIALYSIS- A PROPENSITY MATCHED COHORT STUDY

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
Saif Al-Chalabi ◽  
Tricia Tay ◽  
Rajkumar Chinnadurai ◽  
Philip A Kalra
Keyword(s):  
Risk Factors ◽  
Logistic Regression ◽  
Regression Analysis ◽  
Infective Endocarditis ◽  
Logistic Regression Analysis ◽  
Heart Diseases ◽  
Dialysis Access ◽  
Dialysis Catheter ◽  
Valvular Heart Diseases ◽  
Dialysis Vintage

Abstract Background and Aims Infective endocarditis (IE) is a serious infective complication that usually results in prolonged hospitalisation and is associated with high morbidity and mortality. It is sometimes difficult to promptly diagnose infective endocarditis when a patient receiving hemodialysis presents with signs and symptoms of bacteremia, a delay which can lead to worse outcomes. In this study, we aimed to identify the risk factors that can predict infective endocarditis in haemodialysis patients with bacteremia. Method This retrospective observational study was conducted on all patients diagnosed with infective endocarditis (IE) and receiving maintenance hemodialysis between 2005 and 2018 in Salford Royal Hospital and its satellite dialysis units (catchment population of 1.5 million). The IE patients were propensity score matched in a 1:2 ratio with similar hemodialysis patients without IE but with bacteremia between 2011 and 2015. Propensity scores were generated by using binary logistic regression analysis incorporating age, gender, diabetes status, and dialysis vintage as variables. Logistic regression analysis was used to predict the risk factors associated with developing IE. Statistics were performed using SPSS version-24. Results We had a sample of 105 patients (35 IE vs 70 bacteremia). The median age of the patients was 65 years with a predominance of males (60%). 43% were diabetic, 11.5% were receiving immunosuppression and 72% had a catheter for dialysis access. IE patients had higher peak C-reactive protein (CRP) during admission compared to patients with bacteremia and no IE (253 mg/l vs 152 mg/l, p=0.001). Patients who developed IE had a longer duration of dialysis catheter use than the bacteremia group (150 vs 19 days; p<0.001) (table 1). There was no significant difference between causative microorganisms in both groups. Staphylococcus aureus caused most cases (54% in IE and 47% in bacteremia). Our study showed clearly that patients who had IE had longer hospital stay (45 vs 18 days, p=0.001) with a far higher 30-day mortality rate (54.3% vs 17.1%, p<0.001). Logistic regression analysis showed previous valvular heart diseases (OR: 20.1; p<0.001), a higher peak CRP (OR:1.01; p=0.001), and a longer duration of catheter use (OR: 1.01; p=0.035) as significant predictors for infective endocarditis (table 2). Conclusion Bacteremia in patients receiving hemodialysis through a catheter as access should be actively investigated with a high index of suspicion for IE particularly those having valvular heart diseases, hypertension, higher peak CRP, and those with a longer duration of dialysis catheter usage. Work up may need to include invasive investigations such as transesophageal echocardiogram to confirm or reliably rule out this devastating condition.

Isolated tricuspid valve endocarditis in immunocompetent juvenile patients: a series of three cases

2021 ◽  
Vol 14 (8) ◽  
pp. e244312
Author(s):  
Atanu Chandra ◽  
Shrestha Ghosh ◽  
Uddalak Chakraborty ◽  
Debojyoti Ray
Keyword(s):  
Risk Factors ◽  
Infective Endocarditis ◽  
Tricuspid Valve ◽  
Age Groups ◽  
Case Series ◽  
Venous Catheter ◽  
Diagnostic Challenge ◽  
Native Valve ◽  
Younger Age ◽  
High Index Of Suspicion

Right-sided native valve infective endocarditis is common in patients with congenital or valvular heart disease, intracardiac device, central venous catheter and intravenous drug abuse, usually manifesting in adulthood. However, in the absence of predisposing risk factors and in younger age groups, this disease may pose a diagnostic challenge. We report a case series of three juvenile patients with isolated tricuspid valve infective endocarditis without any risk factors and paucity of cardiovascular findings in two of them, in an attempt to highlight the importance of maintaining a high index of suspicion to arrive a timely diagnosis.

Risk Factors for In-Hospital Mortality During Infective Endocarditis in Patients With Congenital Heart Disease

2008 ◽  
Vol 101 (1) ◽  
pp. 114-118 ◽  
Author(s):  
Masao Yoshinaga ◽  
Koichiro Niwa ◽  
Atsuko Niwa ◽  
Naruhiko Ishiwada ◽  
Hideto Takahashi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Congenital Heart Disease ◽  
Heart Disease ◽  
Infective Endocarditis ◽  
Hospital Mortality ◽  
Congenital Heart
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