Are COPD Patients with Nocturnal REM Sleep-Related Desaturations More Prone to Developing Chronic Respiratory Failure Requiring Long-Term Oxygen Therapy?

Respiration ◽  
2002 ◽  
Vol 69 (2) ◽  
pp. 117-122 ◽  
Author(s):  
Margherita Sergi ◽  
Maurizio Rizzi ◽  
Arnaldo Andreoli ◽  
Marica Pecis ◽  
Claudio Bruschi ◽  
...  
2021 ◽  
Vol 5 (4) ◽  
pp. 199-206
Author(s):  
Naomi Kayauchi ◽  
Eiji Ojima ◽  
Katsunori Kagohashi ◽  
Hiroaki Satoh

Purpose: To investigate the long-term changes in body weight and serum albumin levels in patients with respiratory failure, and those with chronic heart failure, who were treated with home long-term oxygen therapy (LTOT) to understand the current status and contribute to future measures. Methods: Patients with chronic obstructive pulmonary disease (COPD), those with interstitial pneumonia (IP), and those with chronic heart failure (CHF) undergoing home LTOT for 6 months or more between January 2011 and January 2019 were included in the study. Body weight and serum albumin levels were assessed at the start of home LTOT and at the end of the observation period, a minimum of 6 months after commencing home LTOT. Results: Sixty-two patients (29 COPDs, 23 IPs, and 10 CHFs) were included. In COPD patients and IP patients, body weight decreased (P = 0.0017, P = 0.0018, respectively, Wilcoxon signed-rank test). Serum albumin levels decreased in IP patients (P = 0.0185) but not in COPD patients. There was neither significant decrease in body weight nor serum albumin levels in patients with CHF. Conclusion: Chronic respiratory failure patients who have home LTOT were likely to have a decreased nutritional status. In order to provide prolonged home LTOT, medical staff need to pay close attention to the nutritional status of patients receiving home LTOT.


2014 ◽  
Vol 62 (9) ◽  
pp. 1807-1808 ◽  
Author(s):  
Hiroo Wada ◽  
Yoko Akiyama ◽  
Hirotaka Takeda ◽  
Masuo Nakamura ◽  
Hajime Takizawa

2005 ◽  
pp. 81-83
Author(s):  
A. R. Tatarsky ◽  
A. E. Baskakova

Long-term oxygen therapy (LTOT) improves survival of patients with chronic obstructive pulmonary disease (COPD) having severe respiratory failure and chronic hypoxemia. In our study 51 patients received LTOT at home via concentrators (34 males, the mean age, 65.5 ± 7.8 yrs; 17 females, the mean age, 62.8 ± 4.1 yrs). Of them, 37 (72.5 %) survived 6-year period and 14 died (13 males and 1 female). Causes of death were acute respiratory viral infection (in 1 patient), insult (in 1 patient), chronic heart and lung failure (in 12 patients). Survival of patients with chronic restrictive pulmonary diseases was not longer than 3 years. A control group included 45 COPD patients with severe respiratory failure not receiving LTOT (30 males, the mean age, 66.3 ± 8.5 yrs; 15 females, the mean age, 69.1 ± 4.6 yrs). Of them, 16 survived 6 years and 29 died (5 females, the mean age, 72.6 ± 3.6 yrs, 24 males, the mean age, 67.8 ± 5.2 yrs). So, LTOT at home improves survival of COPD patients with severe respiratory failure.


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