Growth Hormone Hypersecretion in a Girl with Neurofibromatosis Type 1 and an Optic Nerve Glioma: Resolution following Chemotherapy

2000 ◽  
Vol 53 (6) ◽  
pp. 305-308 ◽  
Author(s):  
A.J. Drake ◽  
S.P. Lowis ◽  
E. Bouffet ◽  
E.C. Crowne
Keyword(s):  
Growth Hormone ◽  
Optic Nerve ◽  
Neurofibromatosis Type 1 ◽  
Neurofibromatosis Type ◽  
Optic Nerve Glioma

Chemotherapy for Optic Nerve Glioma in A Child with Neurofibromatosis Type-1

2008 ◽  
Vol 32 (3) ◽  
pp. 159-162 ◽  
Author(s):  
Fulvio Parentin ◽  
Marco Rabusin ◽  
Floriana Zennaro ◽  
Dario Catalano Orth ◽  
Stefano Pensiero
Keyword(s):  
Optic Nerve ◽  
Neurofibromatosis Type 1 ◽  
Neurofibromatosis Type ◽  
Optic Nerve Glioma

Significant Improvement of Visual Functions after Removal of an Intracranial Giant Optic Nerve Glioma Revealing Exophytic Growth: Case Report

Neurosurgery ◽  
2006 ◽  
Vol 58 (4) ◽  
pp. E792-E792 ◽  
Author(s):  
Zhiyong Tong ◽  
Masahiko Wanibuchi ◽  
Teiji Uede ◽  
Sumiyoshi Tanabe ◽  
Kazuo Hashi
Keyword(s):  
Optic Nerve ◽  
Neurofibromatosis Type 1 ◽  
Residual Tumor ◽  
Neurofibromatosis Type ◽  
Magnetic Resonance Images ◽  
Optic Nerve Glioma ◽  
Visual Functions ◽  
Relationship Of ◽  
The Relationship

Abstract OBJECTIVE AND IMPORTANCE: Intracranial giant optic nerve gliomas, usually presumed as optic chiasmatic gliomas, are much less common. The architectural tumor form of optic nerve glioma without neurofibromatosis type 1 is usually the expansile-intraneural pattern. The exophytic optic nerve gliomas without neurofibromatosis type 1 are relatively uncommon. Surgical decompression for intracranial optic gliomas frequently leads to clinical improvement, but obvious improvement of vision is rare. We report a case that demonstrated significant recovery of visual function after removal of the intracranial giant optic nerve glioma, revealing exophytic growth. CLINICAL PRESENTATION: A 13-year-old boy presented with visual impairment in both eyes. Magnetic resonance images (MRI) disclosed a 6 cm diameter mass in the suprasellar area. On heavily T2-reversed MRIs, it was obvious that the intracranial portion of right optic nerve was enlarged, and optic tracts were shifted to the left by the tumor. The relationship of the tumor to the chiasma could not be affirmed on MRIs. INTERVENTION: A right frontotemporal craniotomy for decompression of the optic apparatus was performed. After the majority of the tumor was resected, it became clear that the tumor originated in the right optic nerve. The tumor exophytically grew and dislocated the optic chiasma and optic tracts. Significant improvement of visual functions began from the first week after surgery and continued gradually thereafter. The histological diagnosis was pilocytic astrocytoma. A follow-up MRI taken 4 years after surgery showed no regrowth of the residual tumor. CONCLUSION: Giant exophytic gliomas without neurofibromatosis type 1 may arise from the intracranial portion of an isolated optic nerve. Direct visualization of optic component by heavily T2-reversed MRI could more precisely delineate the relationship of the intracranial optic nerve glioma to the optic apparatus. Surgery may be indicated in giant exophytic intracranial optic nerve gliomas and preoperative postulated optic chiasmatic gliomas. Microsurgical resection can induce postoperative visual improvement without regrowth of the residual tumor.

Neurofibromatosis Type 1: Description of a Novel Diagnostic Scoring System in Pediatric Optic Nerve Glioma

2019 ◽  
Vol 212 (4) ◽  
pp. 892-898
Author(s):  
Hadeel Eid ◽  
Gabriel Crevier-Sorbo ◽  
Ahmed Aldraihem ◽  
Flavia Menegotto ◽  
Nagwa Wilson
Keyword(s):  
Optic Nerve ◽  
Neurofibromatosis Type 1 ◽  
Scoring System ◽  
Neurofibromatosis Type ◽  
Optic Nerve Glioma

Anisometropia in children with neurofibromatosis type 1 and unilateral optic nerve glioma

2014 ◽  
Vol 18 (3) ◽  
pp. 255-257 ◽  
Author(s):  
Gad Dotan ◽  
Shay Keren ◽  
Chaim Stolovitch ◽  
Hagit Toledano-Alhadef ◽  
Anat Kesler
Keyword(s):  
Optic Nerve ◽  
Neurofibromatosis Type 1 ◽  
Neurofibromatosis Type ◽  
Optic Nerve Glioma

scholarly journals Optic nerve tortuosity in children with neurofibromatosis type 1

2013 ◽  
Vol 43 (10) ◽  
pp. 1336-1343 ◽  
Author(s):  
Joyce Ji ◽  
Joshua Shimony ◽  
Feng Gao ◽  
Robert C. McKinstry ◽  
David H. Gutmann
Keyword(s):  
Optic Nerve ◽  
Neurofibromatosis Type 1 ◽  
Neurofibromatosis Type

scholarly journals Intraorbital ancient pilocytic astrocytoma of the optic nerve in neurofibromatosis type 1 patient presenting with sudden ocular pain

2018 ◽  
Vol 6 ◽  
pp. 2050313X1876131
Author(s):  
Haesu Lee Motoyama ◽  
Sohsuke Yamada ◽  
Satoko Nakada ◽  
Nozomu Kurose ◽  
Akihide Tanimoto
Keyword(s):  
Optic Nerve ◽  
Neurofibromatosis Type 1 ◽  
Pilocytic Astrocytoma ◽  
English Literature ◽  
Neurofibromatosis Type ◽  
Close Correlation ◽  
Cystic Degeneration ◽  
Ocular Pain ◽  
Fluid Production

Optic nerve pilocytic astrocytoma is an uncommon but well-known entity; however, intraorbital ancient pilocytic astrocytoma of the optic nerve is extremely rarely reported. To our knowledge, this is the first detailed description regarding the intraorbital ancient pilocytic astrocytoma, reported in available English literature, to date. We presented an extremely unusual neurofibromatosis type 1 case of a 17-year-old male’s sudden ocular pain secondary to intraorbital pilocytic astrocytoma of the optic nerve with markedly cystic degeneration, fluid production, and hemorrhage, due to ancient and possibly ruptured glioma. Future prospective studies are required to validate the significance of intraorbital ancient pilocytic astrocytoma arising from the optic nerve and the close correlation with ruptured cystic degeneration and ocular pain, after collecting and investigating a larger number of its cases examined.

Intraorbital Ganglioglioma of Optic Nerve in a Patient With Neurofibromatosis Type 1

2012 ◽  
Vol 32 (4) ◽  
pp. 350-353 ◽  
Author(s):  
Emilija M. Manojlovic Gacic ◽  
Milica K. Skender-Gazibara ◽  
Tatjana M. Gazibara ◽  
Mirjana A. Nagulic ◽  
Igor M. Nikolic
Keyword(s):  
Optic Nerve ◽  
Neurofibromatosis Type 1 ◽  
Neurofibromatosis Type

scholarly journals Pulsatile enophthalmos, severe esotropia, kinked optic nerve and visual loss in neurofibromatosis type-1

2015 ◽  
Vol 8 (3) ◽  
pp. 208
Author(s):  
Virender Sachdeva ◽  
Nazmul Haque ◽  
Avinash Pathengay ◽  
Ramesh Kekunnaya
Keyword(s):  
Optic Nerve ◽  
Neurofibromatosis Type 1 ◽  
Visual Loss ◽  
Neurofibromatosis Type
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