In situ Localization of CD83-Positive Dendritic Cells in Psoriatic Lesions

Dermatology ◽  
2002 ◽  
Vol 204 (2) ◽  
pp. 100-103 ◽  
Author(s):  
Tetsuya Koga ◽  
Hong Duan ◽  
Kazunori Urabe ◽  
Masutaka Furue
Keyword(s):  
Dendritic Cells ◽  
Psoriatic Lesions

In situ demonstration of migration of dendritic cells released from rat small intestine to mesenteric lymph nodes

2001 ◽  
Vol 120 (5) ◽  
pp. A183-A183
Author(s):  
H KOBAYASHI ◽  
H NAGATA ◽  
S MIURA ◽  
T AZUMA ◽  
H SUZUKI ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Small Intestine ◽  
Lymph Nodes ◽  
Rat Small Intestine ◽  
Mesenteric Lymph Nodes ◽  
Mesenteric Lymph

The Relation Between Rat Lymph Node Interdigitating Cells in Situ and Dendritic Cells in Suspension

1985 ◽  
pp. 383-388
Author(s):  
E. W. A. Kamperdijk ◽  
M. van den Berg ◽  
M. Kapsenberg ◽  
E. C. M. Hoefsmit
Keyword(s):  
Dendritic Cells ◽  
Lymph Node ◽  
Interdigitating Cells

scholarly journals In situ Stimulation of CD40 and Toll-like Receptor 3 Transforms Ovarian Cancer–Infiltrating Dendritic Cells from Immunosuppressive to Immunostimulatory Cells

2009 ◽  
Vol 69 (18) ◽  
pp. 7329-7337 ◽  
Author(s):  
Uciane K. Scarlett ◽  
Juan R. Cubillos-Ruiz ◽  
Yolanda C. Nesbeth ◽  
Diana G. Martinez ◽  
Xavier Engle ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Dendritic Cells ◽  
Toll Like Receptor ◽  
Stimulation Of

scholarly journals Cutting Edge: Plasmacytoid Dendritic Cells Provide Innate Immune Protection against Mucosal Viral Infection In Situ

2006 ◽  
Vol 177 (11) ◽  
pp. 7510-7514 ◽  
Author(s):  
Jennifer M. Lund ◽  
Melissa M. Linehan ◽  
Norifumi Iijima ◽  
Akiko Iwasaki
Keyword(s):  
Dendritic Cells ◽  
Viral Infection ◽  
Plasmacytoid Dendritic Cells ◽  
Innate Immune ◽  
Cutting Edge ◽  
Immune Protection

scholarly journals Prolonged Maturation and Enhanced Transduction of Dendritic Cells Migrated from Human Skin Explants After In Situ Delivery of CD40-Targeted Adenoviral Vectors

2002 ◽  
Vol 169 (9) ◽  
pp. 5322-5331 ◽  
Author(s):  
Tanja D. de Gruijl ◽  
Sylvia A. Luykx-de Bakker ◽  
Bryan W. Tillman ◽  
Alfons J. M. van den Eertwegh ◽  
Jan Buter ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
Human Skin ◽  
Adenoviral Vectors ◽  
Skin Explants

scholarly journals Distribution of horseradish peroxidase (HRP)-anti-HRP immune complexes in mouse spleen with special reference to follicular dendritic cells.

1978 ◽  
Vol 79 (1) ◽  
pp. 184-199 ◽  
Author(s):  
L L Chen ◽  
A M Frank ◽  
J C Adams ◽  
R M Steinman
Keyword(s):  
Dendritic Cells ◽  
Horseradish Peroxidase ◽  
Immune Complexes ◽  
Cell Types ◽  
Mouse Spleen ◽  
Follicular Dendritic Cells ◽  
Quantitative Studies ◽  
Wide Range ◽  
Follicular Dendritic

The distribution of immune complexes has been studied in mouse spleen stimulated to contain many germinal centers (GC's). Horseradish peroxidase (HRP)-anti-HRP complexes were used as an appropriately precise and sensitive model. We were primarily interested in the relative abilities of three cell types to interact with complexes: lymphocytes, macrophages, and follicular dendritic cells (FDC's). The latter are distinctive, nonendocytic, stellate cells located primarily at the transition of mantle and GC zones of 2 degrees lymphoid follicles (Chen, L. L., J. C. Adams, and R. M. Steinman, 1978, J. Cell Biol. 77:148). Binding of immune complexes to lymphocytes could not be visualized in situ. Macrophages avidly interiorized complexes into lysosomes, but did not retain them extracellularly. In contrast, FDC's could retain HRP-anti-HRP extracellularly under appropriate conditions, but did not endocytose them. Cytochemical reactivity accumulated progressively on FDC's 1--6 h after administration of complexes i.v., remained stable in amount and location for 1 day, and then was progressively lost over a 1- to 5-day period. Several variables in the association of complexes with macrophages and FDC's were pursued. Only 1 microgram of complexed HRP had to be administered to visualize binding to both cell types. Macrophages interiorized complexes formed in a wide range of HRP/anti-HRP ratios, while FDC's associated with complexes formed in HRP excess only. Quantitative studies with [125I]HRP-anti-HRP demonstrated that 20% of the splenic load of HRP associated with FDC's. Complexes formed with an F(ab')2 anti-HRP were distributed primarily in macrophages. When the levels of the third component of serum complement were depleted by prior treatment with cobra venom factor, uptake of complexes by macrophages was reduced some 50% whereas association with FDC's was abolished. The fact that antigen excess complexes are retained extracellularly strengthens the idea that they are immunogenic. Finally, the association of complexes with FDC's seems to retard the entry of antigen into the GC proper.

scholarly journals In situ Delivery of Antigen to DC-SIGN + CD14 + Dermal Dendritic Cells Results in Enhanced CD8 + T-Cell Responses

2015 ◽  
Vol 135 (9) ◽  
pp. 2228-2236 ◽  
Author(s):  
Cynthia M. Fehres ◽  
Astrid J. van Beelen ◽  
Sven C.M. Bruijns ◽  
Martino Ambrosini ◽  
Hakan Kalay ◽  
...  
Keyword(s):  
Dendritic Cells ◽  
T Cell ◽  
T Cell Responses ◽  
Cd8 T Cell ◽  
Cell Responses
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