Sepsis-Induced Alteration in T-Cell Ca2+ Signaling in Neonatal Rats

Neonatology ◽  
2001 ◽  
Vol 80 (4) ◽  
pp. 300-304
Author(s):  
Mohammad H. Alattar ◽  
Thyyar M. Ravindranath ◽  
Mashkoor A. Choudhry ◽  
Jonathan K. Muraskas ◽  
Shahla Y. Namak ◽  
...  
Keyword(s):  
T Cell ◽  
Neonatal Rats

scholarly journals Induction of precocious intestinal maturation in T-cell deficient athymic neonatal rats

2017 ◽  
Vol 23 (42) ◽  
pp. 7531-7540 ◽  
Author(s):  
Ester Arévalo Sureda ◽  
Catherine Gidlund ◽  
Björn Weström ◽  
Olena Prykhodko
Keyword(s):  
T Cell ◽  
Neonatal Rats ◽  
Intestinal Maturation

scholarly journals Marginal Zone B Cells in Neonatal Rats Express Intermediate Levels of CD90 (Thy-1)

2002 ◽  
Vol 9 (4) ◽  
pp. 187-195 ◽  
Author(s):  
Peter M. Dammers ◽  
Monique E. Lodewijk ◽  
André Zandvoort ◽  
Frans G. M. Kroese
Keyword(s):  
T Cell ◽  
B Cells ◽  
B Cell ◽  
Marginal Zone ◽  
Cell Lineage ◽  
Neonatal Rats ◽  
Adult Rats ◽  
Marginal Zone B Cells ◽  
Immature B Cells

Here we show that marginal zone (MZ)-B cells in rats can already be detected in neonatal spleen from two days after birth. At this time point, morphologically distinct MZs are not present yet and the vast majority of B cells in spleen are located in a concentric area surrounding the T cell zones (PALS). Before MZs are obviously detectable in spleen (14 days after birth), MZ-B cells seem to be enriched at the outer zones of the concentric B cell areas. Similar to adult rats, neonatal MZ-B cells are intermediate-sized cells that express high levels of surface (s)IgM and HIS57 antigen, and low levels of sIgD and CD45R (HIS24). We show here, however, that in contrast to adult MZ-B cells, MZ-B cells (and also recirculating follicular (RF)-B cells) in neonatal rats express higher levels of CD90 (Thy-1). In adult rats, expression of CD90 on the B cell lineage is confined to immature B cells. We speculate that the expression of CD90 on neonatal MZ-B cells may have implications for their responsiveness to polysaccharide (T cell-independent type 2) antigens.

T CELL PROLIFERATIVE RESPONSE FOLLOWING SEPSIS IN NEONATAL RATS

Shock ◽  
1999 ◽  
Vol 11 (Supplement) ◽  
pp. 81
Author(s):  
O. Dallal ◽  
T. Ravindranath ◽  
M. A. Choudhry ◽  
A. Kohn ◽  
J. K. Muraskas ◽  
...  
Keyword(s):  
T Cell ◽  
Proliferative Response ◽  
Neonatal Rats ◽  
Cell Proliferative Response

T-Cell Proliferative Responses following Sepsis in Neonatal Rats

2003 ◽  
Vol 83 (3) ◽  
pp. 201-207 ◽  
Author(s):  
Ousama Dallal ◽  
Thyyar M. Ravindranath ◽  
Mashkoor A. Choudhry ◽  
Annamarie Kohn ◽  
Jonathan K. Muraskas ◽  
...  
Keyword(s):  
T Cell ◽  
Neonatal Rats

Ultrastructural Localization of Acetylcholinesterase in the Arcuate Nucleus and Median Eminence of the Rat

1977 ◽  
Vol 35 ◽  
pp. 440-441
Author(s):  
K.A. Carson ◽  
C.B. Nemeroff ◽  
M.S. Rone ◽  
J.S. Kizer ◽  
J.S. Hanker
Keyword(s):  
Choline Acetyltransferase ◽  
Median Eminence ◽  
Arcuate Nucleus ◽  
Cholinergic Neurons ◽  
Ultrastructural Localization ◽  
Male Rats ◽  
Neonatal Rats ◽  
Good Marker ◽  
Chemical Studies ◽  
High Doses

Biochemical, physiological, pharmacological, and more recently enzyme histo- chemical data have indicated that cholinergic circuits exist in the hypothalamus. Ultrastructural correlates of these pathways such as acetylcholinesterase (AchE) positive neurons in the arcuate nucleus (ARC) and stained terminals in the median eminence (ME) have yet to be described. Initial studies in our laboratories utilizing chemical lesioning and microdissection techniques coupled with microchemical and light microscopic enzyme histo- chemical studies suggested the existence of cholinergic neurons in the ARC which project to the ME (1). Furthermore, in adult male rats with Halasz deafferentations (hypothalamic islands composed primarily of the isolated ARC and the ME) choline acetyltransferase (ChAc) activity, a good marker for cholinergic neurons, was not significantly reduced in the ME and was only somewhat reduced in the ARC (2). Treatment of neonatal rats with high doses of monosodium 1-glutamate (MSG) results in a lesion largely restricted to the neurons of the ARC.

Electron microscope study of the secretory activity of epithelial cells in embryonic thymus

1990 ◽  
Vol 48 (3) ◽  
pp. 382-383
Author(s):  
H. Alasam
Keyword(s):  
Cell Differentiation ◽  
T Cell ◽  
Epithelial Cells ◽  
Electron Density ◽  
Secretory Activity ◽  
T Cell Differentiation ◽  
High Electron ◽  
Transmission Electron ◽  
Medullary Epithelial Cells ◽  
Thymic Factor

The possibility that intrathymic T-cell differentiation involves stem cell-lymphoid interactions in embryos led us to study the ultrastructure of epithelial cell in normal embryonic thymus. Studies in adult thymus showed that it produces several peptides that induce T-cell differentiation. Several of them have been chemically characterized, such as thymosin α 1, thymopoietin, thymic humoral factor or the serum thymic factor. It was suggested that most of these factors are secreted by populations of A and B-epithelial cells.Embryonic materials were obtained from inbred matings of Swiss Albino mice. Thymuses were disected from embryos 17 days old and prepared for transmission electron microscopy. Our studies showed that embryonic thymus at this stage contains undifferentiated and differentiated epithelial cells, large lymphoblasts, medium and few small lymphocytes (Fig. 5). No differences were found between cortical and medullary epithelial cells, in contrast to the findings of Van Vliet et al,. Epithelial cells were mostly of the A-type with low electron density in both cytoplasm and nucleus. However few B-type with high electron density were also found (Fig. 7).

Effects of prenatal administration of PCP on hippocampal neurogenesis in neonatal rats

2010 ◽  
Vol 34 (8) ◽  
pp. S28-S28
Author(s):  
Juan Liu ◽  
Lianxiang Zhang ◽  
Yujun Wen ◽  
Yiwei Zhang ◽  
Toshihito Suzuki
Keyword(s):  
Hippocampal Neurogenesis ◽  
Neonatal Rats

FAILURE TO DETECT ANTI-HTLV-1 ANTIBODY IN A PATIENT WITH ADULT T-CELL LEUKAEMIA/LYMPHOMA

1998 ◽  
Vol 103 (4) ◽  
pp. 1207-1208 ◽  
Author(s):  
Shan-Shun Luo ◽  
Hideto Tamura ◽  
Norio Yokose ◽  
Kiyoyuki Ogata ◽  
Kazuo Dan
Keyword(s):  
T Cell ◽  
Cell Leukaemia
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