Effect of Naringin Supplementation on Cholesterol Metabolism and Antioxidant Status in Rats Fed High Cholesterol with Different Levels of Vitamin E

2001 ◽  
Vol 45 (5) ◽  
pp. 193-201 ◽  
Author(s):  
Myung-Sook Choi ◽  
Kyung-Min Do ◽  
Yong Bok Park ◽  
Seon-Min Jeon ◽  
Tae-Sook Jeong ◽  
...  
Keyword(s):  
Vitamin E ◽  
Antioxidant Status ◽  
Cholesterol Metabolism ◽  
High Cholesterol ◽  
Different Levels

Interactive Effect of Hesperidin and Vitamin E Supplements on Cholesterol Metabolism in High Cholesterol-Fed Rats

2001 ◽  
Vol 71 (1) ◽  
pp. 36-44 ◽  
Author(s):  
Yong Bok Park ◽  
Kyung-Min Do ◽  
Song-Hae Bok ◽  
Mi-Kyung Lee ◽  
Tae-Sook Jeong ◽  
...  
Keyword(s):  
Vitamin E ◽  
Cholesterol Metabolism ◽  
Reductase Activity ◽  
Plasma Cholesterol ◽  
Interactive Effect ◽  
Free Groups ◽  
Dietary Vitamin ◽  
High Cholesterol ◽  
Triglyceride Content ◽  
Coa Reductase

Certain bioflavonoids are potent antioxidants and have pharmacologic effects similar to those of vitamin E. Accordingly, the interactive effect of hesperidin and vitamin E was studied with respect to cholesterol metabolism and the antioxidant status. Hesperidin supplement (0.1%, wt/wt) with comparable levels of vitamin E was provided with a high-cholesterol (1%, wt/wt) diet to rats for 5 weeks. The amount of vitamin E included in the hesperidin-free and hesperidin diets was either a low (low-E) or a normal (normal-E) level. The hesperidin supplement and different levels of dietary vitamin E did not significantly alter the concentrations of plasma triglycerides. However, the inclusion of hesperidin significantly lowered the concentration of plasma cholesterol in both the low-vitamin E group and the normal-vitamin E group compared to the hesperidin-free groups (p < 0.05). The hepatic triglyceride content was significantly lowered by the hesperidin supplement, as opposed to the plasma triglyceride content, regardless of the vitamin E level in the diet. The hepatic HMG-CoA reductase activity was significantly lowered by the hesperidin supplement with both the low-vitamin E and the normal-vitamin E compared to the hesperidin-free groups (p < 0.05). The hepatic HMG-CoA reductase activity was also significantly lowered with an increase in the dietary vitamin E within the hesperidin and hesperidin-free groups. The excretion of fecal neutral sterol and acidic sterols tended to be lower with the hesperidin supplement. Neither dietary hesperidin nor vitamin E significantly changed the hepatic antioxidant enzyme activity. This data indicates that hesperidin lowers the concentration of plasma cholesterol and the hepatic triglyceride content regardless of the dietary vitamin E level. However, the concentration of plasma cholesterol in the hesperidin-free groups was dependent on the dietary vitamin E level. This information may contribute to understanding the interactive effect of hesperidin and vitamin E on cholesterol biosynthesis in high cholesterol-fed rats.

scholarly journals Biometric viscera and blood parameters of meat quails supplemented with inorganic selenium and vitamin E

2017 ◽  
Vol 18 (4) ◽  
pp. 560-575
Author(s):  
Vittor Zancanela ◽  
Antonio Claudio Furlan ◽  
Paulo César Pozza ◽  
Simara Márcia Marcato ◽  
Daiane de Oliveira Grieser ◽  
...  
Keyword(s):  
Vitamin E ◽  
Relative Weight ◽  
Blood Parameters ◽  
Linear Increase ◽  
Spleen Weight ◽  
Quadratic Effect ◽  
Randomized Design ◽  
Inorganic Selenium ◽  
Mineral Interaction ◽  
Different Levels

SUMMARY This study aimed to evaluate biometric viscera and blood parameters of quails at 14 and 35 days of age, supplemented with different levels of inorganic selenium and vitamin E. A completely randomized design was used in a 4×4 factorial scheme (inorganic Se = 0.1125, 0.2250, 0.3375 and 0.4500 mg/kg diet x VE = 10, 23, 36 and 49 IU/kg feed). In the 0-14 days experiment, 2,400 newborn quail were used, distributed in 16 treatments and three replications of 50 birds each. In the 14-35 days experiment, 1,680 14 day-old quails were used with same treatments and three replicates of 35 birds each. At 14 days, the relative spleen weights (P=0.0203) increased linearly as a function of the VE level, while at 35 days, the relative weight of the bursa (P=0.0390) increased linearly as a function of Se concentration. At 14 days, there was a vitamin x mineral interaction (p=0.0097) affecting total cholesterol (TC), and a quadratic effect (P = 0.0138) related to Se and linear reduction levels (P=0.0275) as a function of VE. At 35 days, the TC concentrations (P=0.0055) and triglycerides (TG, P = 0.0220) showed a quadratic effect for Se. The linear increase in spleen weight and bursa after 14 and 35 days respectively suggests an improved immune response as a function of VE and Se supplementation. To achieve the lowest concentration of TC and TG at 35 days of age, supplementation of 0.26 and 0.29 mg/Se/kg/feed, respectively, is recommended.

The effect of polyphenols and vitamin E on the antioxidant status and meat quality of broiler chickens exposed to high temperature

2019 ◽  
Vol 73 (2) ◽  
pp. 111-126 ◽  
Author(s):  
Magdalena Mazur-Kuśnirek ◽  
Zofia Antoszkiewicz ◽  
Krzysztof Lipiński ◽  
Joanna Kaliniewicz ◽  
Sylwia Kotlarczyk ◽  
...  
Keyword(s):  
High Temperature ◽  
Vitamin E ◽  
Meat Quality ◽  
Broiler Chickens ◽  
Antioxidant Status

scholarly journals ІНТЕНСИВНІСТЬ ПРОЦЕСІВ ПОЛ ТА АКТИВНІСТЬ СИСТЕМИ АНТИОКСИДАНТНОГО ЗАХИСТУ У КРОВІ КОРОПІВ ЗА ДІЇ РІЗНОГО РІВНЯ ВІТАМІНУ Е І СЕЛЕНУ В РАЦІОНІ

2016 ◽  
Vol 18 (3(71)) ◽  
pp. 201-204
Author(s):  
S.V. Yurchak ◽  
O.V. Derenj ◽  
O.I. Vishchur ◽  
Yu.M. Zabytivskyi
Keyword(s):  
Lipid Peroxidation ◽  
Vitamin E ◽  
Control Group ◽  
Fish Feed ◽  
Dose Dependent Decrease ◽  
Fat Soluble Vitamins ◽  
And Control ◽  
Dose Dependent ◽  
Experimental Group ◽  
Different Levels

The article consist data about effect of different levels of vitamin E and selenium in the diet of carps during their growing and also informationabout the influence on processes of lipid peroxidation and activity of antioxidant protection in their body.The experiment conducted in three experimental ponds. After wintering there were placed four ears mature females and males carp, six individuals in each group. Supplements of vitamin E administered at a rate of 25 mg/kg and drug «Sel–Plex» the rate of selenium – 0.3 mg/kg were added to further basic diet(BD) of female and male carp first experimental group (EG1). The second experimental group (EG2) received (BD) and vitamin E supplements in an amount of 75 mg / kg, and just as in EG1 – selenium – 0.3 mg/kg of feed.The control group received fish feed without additives vitamins and minerals.Feeding lasted for 30 days, due to the physiological needs of the fish feed. After spawning in fish of research and control group swere taken blood samples for biochemical research.The study led to a dose–dependent decrease (p < 0.01 – 0.001) content of TBA–active products and hydroperoxidase of lipids, but did not significantly effect onsuperoxide dismutase and glutathione peroxidase activity of blood So, the reduction of lipid peroxidation products in the carp’s blood of experimental groups probably was caused by the growth of non–enzymatic level, which is associated with fat–soluble vitamins. 

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