Abdominal Aortic Aneurysms in Hemodialysis Patients with Autosomal Dominant Polycystic Kidney Disease

Nephron ◽  
2001 ◽  
Vol 88 (2) ◽  
pp. 185-186 ◽  
Author(s):  
Akihiko Kato ◽  
Takako Takita ◽  
Mitsuyoshi Furuhashi ◽  
Yukitaka Maruyama ◽  
Akira Hishida
Keyword(s):  
Kidney Disease ◽  
Polycystic Kidney Disease ◽  
Autosomal Dominant ◽  
Abdominal Aortic Aneurysms ◽  
Hemodialysis Patients ◽  
Aortic Aneurysms ◽  
Polycystic Kidney ◽  
Abdominal Aortic ◽  
Autosomal Dominant Polycystic Kidney

scholarly journals Abdominal aortic aneurysms and autosomal dominant polycystic kidney disease.

1996 ◽  
Vol 7 (11) ◽  
pp. 2483-2486
Author(s):  
R Torra ◽  
C Nicolau ◽  
C Badenas ◽  
C Brú ◽  
L Pérez ◽  
...  
Keyword(s):  
Kidney Disease ◽  
Polycystic Kidney Disease ◽  
Autosomal Dominant ◽  
Abdominal Aortic Aneurysms ◽  
Aortic Aneurysms ◽  
Aortic Diameter ◽  
Polycystic Kidney ◽  
Abdominal Aortic ◽  
Healthy Family ◽  
Autosomal Dominant Polycystic Kidney

Although cases of autosomal dominant polycystic kidney disease (ADPKD) associated with abdominal aortic aneurysm have been repeatedly reported in the literature, no systematic studies of the aortas of these patients have been performed. In the study presented here, a sonographic study of the abdominal aorta in 139 ADPKD patients and in 149 healthy family members was carried out. For both groups, an increase in aortic diameter related to age and sex, (being wider in men than women) was found. In ADPKD patients, neither a wider aortic diameter nor a higher prevalence of abdominal aortic aneurysms could be found in any age group. It was concluded that, although these patients are prone to develop aortic aneurysms because of hypertension and associated connective tissue disorders, the presence of abdominal aortic aneurysms should be questioned as a frequent feature of ADPKD.

scholarly journals Association of autosomal dominant polycystic kidney disease, asymptomatic multiple giant coronary arteries aneurysms and abdominal aortic aneurysm: a case report

2020 ◽  
Vol 2020 (12) ◽  
Author(s):  
Abdullah Rida Hindawy ◽  
Baraa Daboul ◽  
Ibrahem Hanafi ◽  
Sami Albitar
Keyword(s):  
Kidney Disease ◽  
Polycystic Kidney Disease ◽  
Coronary Arteries ◽  
Autosomal Dominant ◽  
Systemic Disease ◽  
Aortic Aneurysms ◽  
Polycystic Kidney ◽  
Abdominal Aortic ◽  
Autosomal Dominant Polycystic Kidney ◽  
Multiple Cysts

ABSTRACT Autosomal dominant polycystic kidney disease (ADPKD) is a systemic disease characterized by the formation of multiple cysts in several organs. The formation of aneurysms accompanying this disease is being increasingly reported in the literature, and mutations in PKD-1 and PKD-2 are suspected in this etiology. Although the association between ADPKD and multiple coronary arteries aneurysms (CAA) was reported several times, we are presenting a case with the combination of ADPKD, multiple giant CAAs, abdominal aortic aneurysms and a suspected intracranial aneurysm, which has never been reported. The asymptomatic presentation of these multiple aneurysms might support the recommendations for further diagnostic investigations in these patients.

scholarly journals Splenic artery aneurysm in a patient of autosomal dominant polycystic kidney disease: beyond tenuous concomitance!

2019 ◽  
Vol 12 (4) ◽  
pp. e228552
Author(s):  
Vivek Sood ◽  
Navin Pattanashetti ◽  
Krishan Lal Gupta ◽  
Raja Ramachandran
Keyword(s):  
Kidney Disease ◽  
Polycystic Kidney Disease ◽  
Splenic Artery ◽  
Autosomal Dominant ◽  
Artery Aneurysm ◽  
Aortic Aneurysms ◽  
Splenic Artery Aneurysm ◽  
Polycystic Kidney ◽  
Risk Of Rupture ◽  
Autosomal Dominant Polycystic Kidney

Splenic artery aneurysm (SAA) is rare, with risk of rupture especially if diameter is >2 cm. It is usually asymptomatic and detected incidentally on imaging either in young pregnant women or elderly cirrhotic patients. Extracranial vascular abnormalities known to be associated with autosomal dominant polycystic kidney disease (ADPKD) include ascending aortic aneurysms, dissections of coronary and vertebral arteries and rarely SAA. We describe a rare case of incidentally detected SAA in a patient with end stage renal disease due to ADPKD during evaluation of persistent gross haematuria, with no evidence of cranial or other extracranial aneurysms.

scholarly journals Cinacalcet may suppress kidney enlargement in hemodialysis patients with autosomal dominant polycystic kidney disease

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Shinya Nakatani ◽  
Kozo Nishide ◽  
Senji Okuno ◽  
Eiji Ishimura ◽  
Daijiro Kabata ◽  
...  
Keyword(s):  
Kidney Disease ◽  
Polycystic Kidney Disease ◽  
Autosomal Dominant ◽  
Hemodialysis Patients ◽  
Kidney Volume ◽  
Polycystic Kidney ◽  
Calcium Sensing Receptor ◽  
Total Kidney Volume ◽  
Calcium Sensing ◽  
Autosomal Dominant Polycystic Kidney

AbstractA massively enlarged kidney can impact quality of life of autosomal dominant polycystic kidney disease (ADPKD) patients. A recent in vitro study demonstrated that an allosteric modulator of the calcium sensing receptor decreases adenosine-3′,5′-cyclic monophosphate, an important factor for kidney enlargement in ADPKD. Therefore, the present study was performed to determine whether cinacalcet, a calcium sensing receptor agonist, suppresses kidney enlargement in hemodialysis patients with ADPKD. Alteration of total kidney volume together with clinical parameters was retrospectively examined in 12 hemodialysis patients with ADPKD treated at a single institution in Japan. In the non-cinacalcet group with longer hemodialysis duration (n = 5), total kidney volume had an annual increase of 4.19 ± 1.71% during an overall period of 877 ± 494 days. In contrast, the annual rate of increase in total kidney volume in the cinacalcet group (n = 7) was significantly suppressed after cinacalcet treatment, from 3.26 ± 2.87% during a period of 734 ± 352 days before the start of cinacalcet to − 4.71 ± 6.42% during 918 ± 524 days after initiation of treatment (p = 0.047). The present findings showed that cinacalcet could be a novel therapeutic tool for suppression of kidney enlargement in hemodialysis patients with ADPKD.

scholarly journals Autosomal dominant polycystic kidney disease in hemodialysis patients in southern Brazil

2014 ◽  
Vol 36 (1) ◽  
pp. 18-25
Author(s):  
Everton Fernando Alves ◽  
Luiza Tamie Tsuneto ◽  
Sandra Marisa Pelloso ◽  
Paulo Roberto Aranha Torres ◽  
Guido Luis Gomes Otto ◽  
...  
Keyword(s):  
Kidney Disease ◽  
Polycystic Kidney Disease ◽  
Autosomal Dominant ◽  
Hemodialysis Patients ◽  
Southern Brazil ◽  
Polycystic Kidney ◽  
Autosomal Dominant Polycystic Kidney
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