Severe Arthralgia and Myalgia due to High-Dose Methylprednisolone Pulse Therapy Cured by Potassium Infusion in a Patient with Diffuse Proliferative Lupus Nephritis

Nephron ◽  
2001 ◽  
Vol 87 (1) ◽  
pp. 95-95 ◽  
Author(s):  
Ali Riza Odabas ◽  
Ramazan Cetinkaya ◽  
Yılmaz Selcuk ◽  
Hasan Kaya
Keyword(s):  
Lupus Nephritis ◽  
Pulse Therapy ◽  
Methylprednisolone Pulse Therapy ◽  
High Dose ◽  
Methylprednisolone Pulse ◽  
Proliferative Lupus Nephritis ◽  
High Dose Methylprednisolone

scholarly journals Treatment of Lymphocytic Hypophysitis by High-Dose Methylprednisolone Pulse Therapy.

2003 ◽  
Vol 42 (2) ◽  
pp. 168-173 ◽  
Author(s):  
Keiko YAMAGAMI ◽  
Katsunobu YOSHIOKA ◽  
Haruna SAKAI ◽  
Mariko FUKUMOTO ◽  
Tetsuya YAMAKITA ◽  
...  
Keyword(s):  
Pulse Therapy ◽  
Lymphocytic Hypophysitis ◽  
Methylprednisolone Pulse Therapy ◽  
High Dose ◽  
Methylprednisolone Pulse ◽  
High Dose Methylprednisolone

BENEFICIAL EFFECTS OF METHYLPREDNISOLONE "PULSE" THERAPY IN DIFFUSE PROLIFERATIVE LUPUS NEPHRITIS

The Lancet ◽  
1976 ◽  
Vol 307 (7952) ◽  
pp. 163-166 ◽  
Author(s):  
EdgarS. Cathcart ◽  
MortonA. Scheinberg ◽  
BeldonA. Idelson ◽  
WilliamG. Couser
Keyword(s):  
Lupus Nephritis ◽  
Pulse Therapy ◽  
Methylprednisolone Pulse Therapy ◽  
Methylprednisolone Pulse ◽  
Beneficial Effects ◽  
Proliferative Lupus Nephritis

Precordial T-wave inversion of “cardiac memory” pattern after high-dose methylprednisolone pulse therapy

2008 ◽  
Vol 3 (4) ◽  
pp. 375-378 ◽  
Author(s):  
Johanna Rottensteiner ◽  
Angelika Kaneppele ◽  
Ingrid Stockner ◽  
Carmen Ladurner ◽  
Georgio Panizza ◽  
...  
Keyword(s):  
Pulse Therapy ◽  
Methylprednisolone Pulse Therapy ◽  
High Dose ◽  
Methylprednisolone Pulse ◽  
Cardiac Memory ◽  
T Wave ◽  
Wave Inversion ◽  
High Dose Methylprednisolone ◽  
Memory Pattern

scholarly journals Identification of patients with COVID-19 who are optimal for methylprednisolone pulse therapy

2021 ◽  
Vol 16 ◽  
Author(s):  
Shosei Ro ◽  
Naoki Nishimura ◽  
Ryosuke Imai ◽  
Yutaka Tomishima ◽  
Clara So ◽  
...  
Keyword(s):  
Cytomegalovirus Infection ◽  
Elderly Person ◽  
Pulse Therapy ◽  
Methylprednisolone Pulse Therapy ◽  
High Dose ◽  
Pulmonary Aspergillosis ◽  
Methylprednisolone Pulse ◽  
High Dose Methylprednisolone ◽  
Significant Difference

Background: Corticosteroids have been reported to reduce the mortality rates in patients with coronavirus disease 2019 (COVID-19). Additionally, the role of high-dose methylprednisolone pulse therapy in reducing mortality in critically ill patients has also been documented. The purpose of this study is to identify patients with COVID-19 who are suitable for methylprednisolone pulse therapy.Methods: This was a retrospective study that included patients with COVID-19 receiving methylprednisolone pulse therapy (>250 mg/day for 3 days) with subsequent tapering doses at our hospital between June 2020 and January 2021. We examined the differences in background clinical factors between the surviving group and the deceased group.Results: Of 156 patients that received steroid therapy, 17 received methylprednisolone pulse therapy. Ten patients recovered (surviving group) and seven patients died (deceased group). The median age of the surviving and deceased groups was 64.5 years (range, 57-85) and 79 years (73-90), respectively, with a significant difference (p=0.004). Five of the deceased patients (71%) had developed serious complications associated with the cause of death, including pneumothorax, pneumomediastinum, COVID-19-associated pulmonary aspergillosis, cytomegalovirus infection, and bacteremia. On the other hand, of the 10 survivors, only one elderly person had cytomegalovirus infection and the rest recovered without complications.Conclusion: Administration of methylprednisolone pulse therapy with subsequent tapering may be an effective treatment in patients with COVID-19 up to the age of early 70s; however, severe complications may be seen in elderly patients.

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