Effect of an α-Adrenergic Blocker, and ACE Inhibitor and Hydrochlorothiazide on Blood Pressure and on Renal Function in Type 2 Diabetic Patients with Hypertension and Albuminuria

Nephron ◽  
1998 ◽  
Vol 80 (2) ◽  
pp. 175-182 ◽  
Author(s):  
Rita Rachmani ◽  
Zohar Levi ◽  
Inna Slavachevsky ◽  
Elizabeth Half-Onn ◽  
Mordchai Ravid
Keyword(s):  
Blood Pressure ◽  
Renal Function ◽  
Ace Inhibitor ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Adrenergic Blocker ◽  
Type 2 Diabetic

scholarly journals The effect of HIV infection on glycaemia and renal function in type 2 diabetic patients

PLoS ONE ◽  
2018 ◽  
Vol 13 (6) ◽  
pp. e0199946 ◽  
Author(s):  
Siyabonga P. Khoza ◽  
Nigel J. Crowther ◽  
Sindeep Bhana
Keyword(s):  
Renal Function ◽  
Hiv Infection ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
Type 2 Diabetic

Carotid artery intima-media thickness is associated with insulin-mediated glucose disposal in nondiabetic normotensive offspring of type 2 diabetic patients

2007 ◽  
Vol 292 (1) ◽  
pp. E347-E352 ◽  
Author(s):  
Marina Cardellini ◽  
Maria Adelaide Marini ◽  
Simona Frontoni ◽  
Marta Letizia Hribal ◽  
Francesco Andreozzi ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Blood Cell ◽  
White Blood Cell Count ◽  
White Blood Cell ◽  
Glucose Disposal ◽  
Diabetic Patients ◽  
Blood Cell Count ◽  
Type 2 Diabetic Patients ◽  
Type 2 Diabetic

The aim of this study was to investigate whether insulin resistance is independently associated with early manifestations of atherosclerosis. To this end, 176 normotensive offspring of type 2 diabetic patients were subjected to euglycemic hyperinsulinemic clamp to assess insulin sensitivity. Early atherosclerosis was studied by ultrasonography of the common carotid artery. Of the total 176 subjects, 145 were glucose tolerant, 18 had impaired fasting glucose, and 13 had impaired glucose tolerance. Univariate correlations showed that age, body mass index, waist, blood pressure, 2-h postchallenge glucose, fasting insulin, triglycerides, interleukin-6, fibrinogen, and white blood cell count were significantly correlated with carotid intima-media thickness (IMT), whereas HDL cholesterol and glucose disposal showed a negative correlation. A stepwise multivariate regression analysis including sex, age, waist circumference, smoking status, systolic blood pressure, diastolic blood pressure, triglyceride, HDL cholesterol, 2-h postchallenge glucose, plasma IL-6, fibrinogen, white blood cell count, insulin-stimulated glucose disposal, and fasting insulin showed that the four variables that remained significantly associated with carotid IMT were waist circumference, insulin-stimulated glucose disposal, white blood cell count, and diastolic blood pressure, accounting for 33.7% of its variation. These findings support the concept that insulin sensitivity, rather than plasma insulin levels, is associated with early atherosclerosis in nondiabetic normotensive offspring of type 2 diabetic patients.

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