Cloning and Sequencing of Human Oncodevelopmental Soluble Placental Tissue Protein 17 (PP17): Homology with Adipophilin and the Mouse Adipose Differentiation-Related Protein

Tumor Biology ◽  
1999 ◽  
Vol 20 (4) ◽  
pp. 184-192 ◽  
Author(s):  
Nandor G. Than ◽  
Balazs Sumegi ◽  
Gabor N. Than ◽  
Gyula Kispal ◽  
Hans Bohn
Keyword(s):  
Placental Tissue ◽  
Related Protein ◽  
Cloning And Sequencing ◽  
Tissue Protein ◽  
Adipose Differentiation

scholarly journals Effect of Adipose Differentiation-Related Protein (ADRP) on Glucose Uptake of Skeletal Muscle

2009 ◽  
Vol 33 (3) ◽  
pp. 206
Author(s):  
Yun Hyi Ku ◽  
Min Kim ◽  
Sena Kim ◽  
Ho Seon Park ◽  
Han-Jong Kim ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Glucose Uptake ◽  
Related Protein ◽  
Adipose Differentiation

Dynamics and synthesis of new placental tissue protein PP19

Placenta ◽  
1992 ◽  
Vol 13 ◽  
pp. 289-302
Author(s):  
Masaomi Takayama ◽  
Keiichi Isaka ◽  
Yasunobu Suzuki ◽  
Hitoshi Funayama ◽  
Yoshichika Suzuki ◽  
...  
Keyword(s):  
Placental Tissue ◽  
Tissue Protein

scholarly journals Immunochemical Measurement of Placental Tissue Protein 4 in Serum

1986 ◽  
Vol 34 (5) ◽  
pp. 2191-2195 ◽  
Author(s):  
SYOICHI SHIROTAKE ◽  
NORIYUKI INABA ◽  
YORIKO OHTA ◽  
ICHIO FUKAZAWA ◽  
HIROYOSHI TAKAMIZAWA ◽  
...  
Keyword(s):  
Placental Tissue ◽  
Tissue Protein

scholarly journals Retinyl Ester Homeostasis in the Adipose Differentiation-related Protein-deficient Retina

2008 ◽  
Vol 283 (36) ◽  
pp. 25091-25102 ◽  
Author(s):  
Yoshikazu Imanishi ◽  
Wenyu Sun ◽  
Tadao Maeda ◽  
Akiko Maeda ◽  
Krzysztof Palczewski
Keyword(s):  
Related Protein ◽  
Retinyl Ester ◽  
Adipose Differentiation

Role of the fetal parathyroid glands and parathyroid hormone-related protein in the regulation of placental transport of calcium, magnesium and inorganic phosphate

1991 ◽  
Vol 3 (4) ◽  
pp. 447 ◽  
Author(s):  
RJ MacIsaac ◽  
JA Heath ◽  
CP Rodda ◽  
JM Moseley ◽  
AD Care ◽  
...  
Keyword(s):  
Parathyroid Hormone ◽  
Autologous Blood ◽  
Placental Tissue ◽  
Parathyroid Glands ◽  
Related Protein ◽  
Tissue Extracts ◽  
Parathyroid Hormone Related Protein ◽  
Placental Transport ◽  
Calcium Magnesium

The plasma Ca concentration of the fetus is maintained higher than maternal levels by active placental transport. Ca, Mg and PO4 accumulation by the fetus is mainly associated with skeletal growth. The fetal parathyroid glands are essential for maintenance of elevated plasma Ca, which is necessary for the stimulation of fetal osteoblasts and mineralization of cartilage and osteoid. Fetal thyroparathyroidectomy (TxPTx) results in a decreased activity of the placental Ca pump. The presence of a parathyroid hormone-related protein (PTHrP) has been demonstrated in fetal parathyroid glands and placental tissue. Extracts of fetal parathyroid glands and purified PTHrP, as well as recombinant PTHrP (1-84, 1-108 and 1-141), stimulate Ca and Mg but not PO4 transport across the placenta of TxPTx-ized fetuses perfused with autologous blood in the absence of the fetus. Parathyroid hormone (PTH) and the N-terminal region of PTHrP do not stimulate placental Ca and Mg transport. It is concluded that a mid-molecule region of this novel hormone may be required to stimulate placental Ca transfer and contribute to the regulation of fetal Ca homeostasis.

scholarly journals Protection against Fatty Liver but Normal Adipogenesis in Mice Lacking Adipose Differentiation-Related Protein

2006 ◽  
Vol 26 (3) ◽  
pp. 1063-1076 ◽  
Author(s):  
Benny Hung-Junn Chang ◽  
Lan Li ◽  
Antoni Paul ◽  
Susumu Taniguchi ◽  
Vijayalakshmi Nannegari ◽  
...  
Keyword(s):  
Fatty Liver ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Lipid Uptake ◽  
Related Protein ◽  
Outer Leaflet ◽  
Adipose Differentiation ◽  
Deficient Mice

ABSTRACT Adipose differentiation-related protein (ADFP; also known as ADRP or adipophilin), is a lipid droplet (LD) protein found in most cells and tissues. ADFP expression is strongly induced in cells with increased lipid load. We have inactivated the Adfp gene in mice to better understand its role in lipid accumulation. The Adfp-deficient mice have unaltered adipose differentiation or lipolysis in vitro or in vivo. Importantly, they display a 60% reduction in hepatic triglyceride (TG) and are resistant to diet-induced fatty liver. To determine the mechanism for the reduced hepatic TG content, we measured hepatic lipogenesis, very-low-density lipoprotein (VLDL) secretion, and lipid uptake and utilization, all of which parameters were shown to be similar between mutant and wild-type mice. The finding of similar VLDL output in the presence of a reduction in total TG in the Adfp-deficient liver is explained by the retention of TG in the microsomes where VLDL is assembled. Given that lipid droplets are thought to form from the outer leaflet of the microsomal membrane, the reduction of TG in the cytosol with concomitant accumulation of TG in the microsome of Adfp −/− cells suggests that ADFP may facilitate the formation of new LDs. In the absence of ADFP, impairment of LD formation is associated with the accumulation of microsomal TG but a reduction in TG in other subcellular compartments.

scholarly journals Homology modelling and molecular dynamics studies of human placental tissue protein 13 (galectin-13)

2001 ◽  
Vol 14 (11) ◽  
pp. 875-880 ◽  
Author(s):  
Balázs Visegrády ◽  
Nándor G. Than ◽  
Ferenc Kilár ◽  
Balázs Sümegi ◽  
Gábor N. Than ◽  
...  
Keyword(s):  
Molecular Dynamics ◽  
Homology Modelling ◽  
Placental Tissue ◽  
Tissue Protein ◽  
Human Placental Tissue
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