Heme Metabolism and Lipid Peroxidation in Rat Kidney Hexachlorobenzene–Induced Porphyria: A Compartmentalized Study of Biochemical Pathogenic Mechanisms

1999 ◽  
Vol 23 (1) ◽  
pp. 20-26 ◽  
Author(s):  
María del Carmen Fernández-Tomé ◽  
Silvia C. Billi de Catabbi ◽  
Carmen Aldonatti ◽  
Leonor C. San Martin de Viale ◽  
Norma B. Sterin-Speziale
Keyword(s):  
Lipid Peroxidation ◽  
Rat Kidney ◽  
Pathogenic Mechanisms ◽  
Heme Metabolism

Acute lead exposure induces renal haeme oxygenase-1 and decreases urinary Na excretion

2003 ◽  
Vol 22 (5) ◽  
pp. 237-244 ◽  
Author(s):  
Hilda Vargas ◽  
Carlos Castillo ◽  
Francisco Posadas ◽  
Bruno Escalante
Keyword(s):  
Oxidative Stress ◽  
Lipid Peroxidation ◽  
Renal Function ◽  
Lead Exposure ◽  
Lead Acetate ◽  
Single Injection ◽  
Rat Kidney ◽  
Kidney Cortex ◽  
Tin Protoporphyrin ◽  
Pb Exposure

The effects of acute lead exposure on renal function, lipid peroxidation and the expression of haeme oxygenase (HO) in rat kidney were determined. A single injection of lead acetate (50 mg Pb/kg) was given to rats. Changes in renal function, characterized by a significant reduction in the Na excretion was observed six hours after Pb exposure; this effect persisted for 24 hours. TBARS levels increased in kidney cortex 24 hours after Pb administration. In kidney cortex, Pb exposure affected the expression of HO-1, a renal protein associated with oxidative stress. HO-1 mRNA increased 2.3-fold, three hours after Pb administration and remained increased for six, 12 and 24 hours. HO enzymatic activity and HO-1 protein increased six and three hours after Pb administration, respectively, and remained increased at 24 hours. HO inhibition by tin-protoporphyrin, potentiated Pb-induced increase in TBARS and prevented the Pb-induced reduction in Na excretion. Our data suggest that Pb may be acting through the generation of oxidant products and induction of HO.

scholarly journals Toxic Effects of Methotrexate on Rat Kidney Recovered by Crocin as a Consequence of Antioxidant Activity and Lipid Peroxidation Prevention

2020 ◽  
Vol 24 (1) ◽  
pp. 39-46
Author(s):  
Cyrus Jalili ◽  
Ali Ghanbari ◽  
Shiva Roshankhah ◽  
Mohammad Reza Salahshoor ◽  
◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Antioxidant Activity ◽  
Rat Kidney ◽  
Toxic Effects

l-Arginine infusion after ischaemia-reperfusion of rat kidney enhances lipid peroxidation

1996 ◽  
Vol 13 (1) ◽  
pp. 9-17 ◽  
Author(s):  
Jean-Paul Cristol ◽  
Christoph Thiemermann ◽  
Marie-Christine Guerin ◽  
Jean Torreilles ◽  
AndréCrastes de Paulet
Keyword(s):  
Lipid Peroxidation ◽  
Rat Kidney ◽  
Arginine Infusion ◽  
Ischaemia Reperfusion

Decreased lipid peroxidation in the rat kidney during gestation

1987 ◽  
Vol 145 (1) ◽  
pp. 134-138 ◽  
Author(s):  
Thomas P.A. Devasagayam ◽  
U. Tarachand
Keyword(s):  
Lipid Peroxidation ◽  
Rat Kidney

scholarly journals Effects of Cadmium Exposure on Lipid Peroxidation and Chlorinative Stress of Rat Kidney

2015 ◽  
Vol 5 (1) ◽  
pp. 1-5 ◽  
Author(s):  
Eko Suhartono ◽  
◽  
Triawanti Triawanti ◽  
Amin Setyo Leksono
Keyword(s):  
Lipid Peroxidation ◽  
Rat Kidney ◽  
Cadmium Exposure

Effects of captopril and losartan on lipid peroxidation, protein oxidation and nitric oxide release in diabetic rat kidney

2003 ◽  
Vol 69 (4) ◽  
pp. 223-227 ◽  
Author(s):  
Dilek Yavuz ◽  
Belgin Küçükkaya ◽  
Goncagül Haklar ◽  
Önder Ersöz ◽  
Emel Akoğlu ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Lipid Peroxidation ◽  
Protein Oxidation ◽  
Rat Kidney ◽  
Diabetic Rat ◽  
Nitric Oxide Release
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