Influence of Fresh Frozen Plasma, Red Blood Cell Packs, and Hydroxyethyl Starch on Phagocytosis of Leukocytes – An in vitro Model

2000 ◽  
Vol 27 (1) ◽  
pp. 23-29
Author(s):  
T. Schulte ◽  
M. Duchrow ◽  
T.H.K. Schiedeck ◽  
H.-P. Bruch
Keyword(s):  
Blood Cell ◽  
Hydroxyethyl Starch ◽  
Red Blood Cell ◽  
In Vitro Model ◽  
Fresh Frozen Plasma ◽  
Fresh Frozen ◽  
Vitro Model ◽  
Frozen Plasma

scholarly journals Red blood cell transfusion is associated with further bleeding and fresh-frozen plasma with mortality in nonvariceal upper gastrointestinal bleeding

Transfusion ◽  
2015 ◽  
Vol 56 (4) ◽  
pp. 816-826 ◽  
Author(s):  
Kavitha Subramaniam ◽  
Katrina Spilsbury ◽  
Oyekoya T. Ayonrinde ◽  
Faye Latchmiah ◽  
Syed A. Mukhtar ◽  
...  
Keyword(s):  
Blood Cell ◽  
Gastrointestinal Bleeding ◽  
Red Blood Cell ◽  
Upper Gastrointestinal Bleeding ◽  
Fresh Frozen Plasma ◽  
Red Blood Cell Transfusion ◽  
Fresh Frozen ◽  
Upper Gastrointestinal ◽  
Frozen Plasma

203. The Influence of Hemoglobine Levels, Red Blood Cell and Fresh Frozen Plasma Use on Postoperative Deposition and Outcome

2009 ◽  
Vol 9 (10) ◽  
pp. 107S-108S
Author(s):  
Albert Pull Ter Gunne ◽  
Richard Skolasky ◽  
Hillary Ross ◽  
David Cohen
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Fresh Frozen Plasma ◽  
Fresh Frozen ◽  
Frozen Plasma

scholarly journals Evolution of Practices in a French Trauma Centre: Decrease in Blood Transfusions and Fresh Frozen Plasma to Red Blood Cell Ratios

2021 ◽  
Vol 49 (5) ◽  
pp. 365-372
Author(s):  
Cyril Pernod ◽  
◽  
Laurie Fraticelli ◽  
Guillaume Marcotte ◽  
Bernard Floccard ◽  
...  
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Fresh Frozen Plasma ◽  
Trauma Centre ◽  
Blood Transfusions ◽  
Fresh Frozen ◽  
Frozen Plasma

The Use of Purine Analogues During Induction and Consolidation Therapy of Acute Myeloid Leukemia Does Not Increase the Need for More Frequent Transfusions of Red Blood Cell Concentrates, Platelet Concentrates and Fresh Frozen Plasma

Blood ◽  
2010 ◽  
Vol 116 (21) ◽  
pp. 4358-4358
Author(s):  
Marek Seweryn ◽  
Dariusz Kata ◽  
Slawomira Kyrcz-Krzemien
Keyword(s):  
Blood Cell ◽  
Induction Therapy ◽  
Red Blood Cell ◽  
Fresh Frozen Plasma ◽  
Consolidation Therapy ◽  
Platelet Concentrates ◽  
Purine Analogues ◽  
Consolidation Treatment ◽  
Fresh Frozen ◽  
Frozen Plasma

Abstract Abstract 4358 Background Addition of purine analogues to standard induction therapy of acute myeloid leukemia (AML) had previously been demonstrated to increase complete remission rate and does not aggravate infectious complications. The aim of this study was to analyze whether the use of cladribine or fludarabine during induction and consolidation treatment increase the need for more frequent transfusions of red blood cell concentrates, platelet concentrates and fresh frozen plasma. Material and methods 118 AML patients, included in two consecutive randomized trials between 1999–2006 in a single centre were analyzed. Induction therapy consisted of daunorubicin + cytarabine (DA-7, n=53) alone or in combination with cladribine or fludarabine (DAC-7 + DAF-7, n=65). Consolidation included one course of high-dose AraC + mitoxantrone and one course of high-dose AraC +/− purine analogues. A median age was 45(17-58) years and 48(20-60) years for patients treated with and without purine analogues, respectively. Results During induction treatment 7 (1-19) units of red blood cell concentrates (median and range) was transfused in the group with purine analogues compared to 6 (1-23) in the group without purine analogues, p=0,24. Number of transfused platelet concentrates bags was 6 (1-30) in the group of purine analogues and 7 (0-19) in the group without purine analogues, p = 0.49. In the group with purine analogues 0 (0-31) units of fresh frozen plasma was transfused compared to 0 (0-26) in the group without purine analogues, p = 0.91. During HAM consolidation therapy 3 (0-11) units of red blood cell concentrates was transfused in the group with purine analogues compared to 2 (0-9) in the group without purine analogues, p = 0.15. Number of transfused platelet concentrates bags in the group with purine analogues was 2 (0-8) vs. 2 (0-12) in the group without purine analogues, p = 0.25. In the course of HAM consolidation treatment - 0 (0-56) units of fresh frozen plasma was transfused in the group with purine analogues compared to 0 (0-0) in the group without purine analogues, p = 0.027. During HD Ara-C consolidation therapy 3 (0-7) units of red blood cell concentrates was transfused in the group with purine analogues compared to 2 (0-5) in the group without purine analogues, p = 0.03. Number of transfused platelet concentrates bags in the group treated with purine analogues was 3 (1-12) vs. 3 (1-6) in the group without purine analogues, p = 0.61. In the course of HD Ara-C consolidation treatment 0 (0-9) units of fresh frozen plasma was transfused in the group with purine analogues compared to 0 (0-11) in the group without purine analogues, p=0,34. Conclusions The vast majority of the obtained results did not reveal any significant differences between the group of AML patients treated with or without purine analogues. During HAM consolidation treatment statistical significance for more fresh frozen plasma units transfused was shown in the patients treated with purine analogues, although the median value was the same in both groups (0). This situation was random and independent of prior use of purine analogues in the induction therapy, because in one of the woman-patient gynecological complications and DIC occurred (bleeding from uterine fibroids). This situation required intensive supportive therapy including fresh frozen plasma transfusions. In one case 56 units of fresh frozen plasma was transfused and in second arm of the study was not applied a plasma transfusions in any patient. Also during second (HD Ara-C) consolidation treatment number of transfused units of RBC's concentrates was significant higher in the group of patients treated with purine analogues, although the median values were similar (3 vs 2). These differences may arise from the fact that in some patients - especially in group of patients treated with purine analogues who obtained the better results of therapy – second HD Ara-C treatment was also more often followed by mobilization and collection of stem cells from peripheral blood for transplantation. In the procedure of stem cells collection a higher hematocrit value is recommended – so frequent decision for RBC's transfusions was made in this group of patients. We conclude that the use of purine analogues in the treatment of AML patients does not increase the need for more frequent transfusions of red blood cell concentrates, platelet concentrates and fresh frozen plasma. Disclosures: No relevant conflicts of interest to declare.

scholarly journals Metagenomics analysis of red blood cell and fresh-frozen plasma units

Transfusion ◽  
2017 ◽  
Vol 57 (7) ◽  
pp. 1787-1800 ◽  
Author(s):  
Pierre Lau ◽  
Samuel Cordey ◽  
Francisco Brito ◽  
Diderik Tirefort ◽  
Thomas J. Petty ◽  
...  
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Fresh Frozen Plasma ◽  
Fresh Frozen ◽  
Frozen Plasma ◽  
Metagenomics Analysis
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