Adjuvant and Neoadjuvant Hormonal Therapy for Prostate Cancer

1999 ◽  
Vol 36 (6) ◽  
pp. 549-558 ◽  
Author(s):  
C.J. Tyrrell
Keyword(s):  
Prostate Cancer ◽  
Hormonal Therapy ◽  
Neoadjuvant Hormonal Therapy

Neoadjuvant hormonal therapy and external-beam radiotherapy versus external-beam irradiation alone for prostate cancer

2009 ◽  
Vol 185 (2) ◽  
pp. 101-108 ◽  
Author(s):  
Michael Pinkawa ◽  
Marc D. Piroth ◽  
Branka Asadpour ◽  
Bernd Gagel ◽  
Karin Fischedick ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Hormonal Therapy ◽  
External Beam Radiotherapy ◽  
External Beam ◽  
Beam Irradiation ◽  
External Beam Irradiation ◽  
Neoadjuvant Hormonal Therapy

Obesity is a predictor in prostate cancer patients receiving prostatectomy after neoadjuvant hormonal therapy

2019 ◽  
Vol 106 (2) ◽  
pp. 133-138
Author(s):  
Lijiang Sun ◽  
Ting Xu ◽  
Xiaoliang Yuan ◽  
Feng Liu ◽  
Fengju Guan ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Hormonal Therapy ◽  
Roc Curve ◽  
Normal Weight ◽  
Castration Resistance ◽  
Free Survival ◽  
Positive Margins ◽  
Neoadjuvant Hormonal Therapy ◽  
Pathologic Features ◽  
Significant Difference

Objective: This study aimed to investigate the relationship between obesity and pathologic features and biochemical recurrence in patients with prostate cancer (PCa) undergoing radical prostatectomy (RP) after neoadjuvant hormonal therapy (NHT). Methods: A total of 422 consecutive patients with clinically localized PCa who received NHT before RP were retrospectively analyzed. Unconditional multiple logistic regression was used to estimate odds ratios (ORs) and 95% confidence intervals (CIs) regarding probability. A receiver operating characteristic (ROC) curve was used to assess the efficacy of the predictive variables. Castration resistance free survival curves were obtained using the Kaplan-Meier method, and were compared using the log-rank test. Results: Being overweight was associated with an increased risk of positive margins (OR 2.281; 95% CI 1.292–4.028) after adjusting for potential confounders. The area under the ROC curve for overweight patients was larger than that for patients in the normal weight range. There was no significant difference between the overweight and normal weight groups regarding castration resistance free survival. Conclusions: Being overweight was associated with positive margins in patients with PCa undergoing RP after NHT.

Expression of clusterin in prostate cancer correlates with gleason score but not with prognosis in patients undergoing radical prostatectomy without neoadjuvant hormonal therapy

Urology ◽  
2006 ◽  
Vol 68 (3) ◽  
pp. 609-614 ◽  
Author(s):  
Hideaki Miyake ◽  
Mototsugu Muramaki ◽  
Toshifumi Kurahashi ◽  
Kazuki Yamanaka ◽  
Isao Hara ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Radical Prostatectomy ◽  
Gleason Score ◽  
Hormonal Therapy ◽  
Neoadjuvant Hormonal Therapy
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